Details for: ADD1

Gene ID: 118

Symbol: ADD1

Ensembl ID: ENSG00000087274

Description: adducin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 500.6261
    Cell Significance Index: -77.8700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 317.5719
    Cell Significance Index: -80.5500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 219.5121
    Cell Significance Index: -90.4300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 178.9048
    Cell Significance Index: -84.4700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 169.4370
    Cell Significance Index: -68.8400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 153.4842
    Cell Significance Index: -78.9500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 72.7316
    Cell Significance Index: -69.4400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 67.4233
    Cell Significance Index: -83.1300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 28.1575
    Cell Significance Index: -75.4300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 24.4672
    Cell Significance Index: -75.1500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 21.5633
    Cell Significance Index: -85.0900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 17.7466
    Cell Significance Index: -38.8400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 11.1400
    Cell Significance Index: 132.8000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.2896
    Cell Significance Index: 227.4900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.7333
    Cell Significance Index: 172.2700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.2141
    Cell Significance Index: 444.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.7341
    Cell Significance Index: 344.1300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.6835
    Cell Significance Index: 303.4800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.5978
    Cell Significance Index: 573.1200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5288
    Cell Significance Index: 166.2900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.4162
    Cell Significance Index: 91.3700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3339
    Cell Significance Index: 164.0100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.0191
    Cell Significance Index: 62.6400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.0118
    Cell Significance Index: 138.9500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.8199
    Cell Significance Index: 42.7100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8019
    Cell Significance Index: 61.5400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7932
    Cell Significance Index: 548.5900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.7453
    Cell Significance Index: 10.7200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6870
    Cell Significance Index: 38.5500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6130
    Cell Significance Index: 17.1300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.6092
    Cell Significance Index: 11.8900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5788
    Cell Significance Index: 16.6800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5616
    Cell Significance Index: 507.1000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4962
    Cell Significance Index: 12.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4528
    Cell Significance Index: 247.2900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3931
    Cell Significance Index: 26.4300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3282
    Cell Significance Index: 145.1200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3029
    Cell Significance Index: 13.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2837
    Cell Significance Index: 12.5500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2288
    Cell Significance Index: 43.5500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2241
    Cell Significance Index: 11.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1800
    Cell Significance Index: 30.7300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1679
    Cell Significance Index: 21.5200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1533
    Cell Significance Index: 5.8100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1228
    Cell Significance Index: 231.3100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1225
    Cell Significance Index: 188.5200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1224
    Cell Significance Index: 4.3000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1089
    Cell Significance Index: 148.0200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1029
    Cell Significance Index: 189.7400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0625
    Cell Significance Index: 39.7000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0469
    Cell Significance Index: 21.2700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0268
    Cell Significance Index: -19.8400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0432
    Cell Significance Index: -1.0400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0552
    Cell Significance Index: -40.5000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0662
    Cell Significance Index: -9.6200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0663
    Cell Significance Index: -1.7700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0727
    Cell Significance Index: -55.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0777
    Cell Significance Index: -48.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1113
    Cell Significance Index: -62.7600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.1208
    Cell Significance Index: -11.9500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1253
    Cell Significance Index: -5.8400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1474
    Cell Significance Index: -17.3900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1644
    Cell Significance Index: -3.5100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1745
    Cell Significance Index: -2.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1778
    Cell Significance Index: -18.1600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2118
    Cell Significance Index: -44.6100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2558
    Cell Significance Index: -73.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2780
    Cell Significance Index: -13.0700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2973
    Cell Significance Index: -38.4100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2982
    Cell Significance Index: -6.4600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3085
    Cell Significance Index: -16.2000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.3166
    Cell Significance Index: -51.5000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3495
    Cell Significance Index: -5.9900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3899
    Cell Significance Index: -29.0600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4292
    Cell Significance Index: -48.9900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4860
    Cell Significance Index: -12.7800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.4907
    Cell Significance Index: -57.1900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5007
    Cell Significance Index: -57.3600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5686
    Cell Significance Index: -19.7600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.6585
    Cell Significance Index: -46.5700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6921
    Cell Significance Index: -72.0600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.7390
    Cell Significance Index: -21.0900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8384
    Cell Significance Index: -66.4100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.8554
    Cell Significance Index: -18.7300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.9578
    Cell Significance Index: -26.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.9635
    Cell Significance Index: -20.5200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.0061
    Cell Significance Index: -20.8700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.0904
    Cell Significance Index: -13.5300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.1256
    Cell Significance Index: -10.3700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.2090
    Cell Significance Index: -32.3400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.2396
    Cell Significance Index: -76.0000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.2910
    Cell Significance Index: -41.3500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.3982
    Cell Significance Index: -34.9500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.4012
    Cell Significance Index: -37.5500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.4418
    Cell Significance Index: -41.3300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.4522
    Cell Significance Index: -33.5500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.4846
    Cell Significance Index: -43.6000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -1.5613
    Cell Significance Index: -22.4200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.5661
    Cell Significance Index: -32.7800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.5732
    Cell Significance Index: -33.3900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Actin-binding protein**: Adducin 1 is a member of the adducin family, which is known for its ability to bind actin filaments. This interaction is critical for regulating actin filament dynamics and maintaining cellular structure. 2. **Cytoskeletal organization**: Adducin 1 is involved in organizing the actin cytoskeleton, which is essential for cell shape, movement, and intracellular transport. 3. **Cellular responses to stimuli**: The protein is also involved in cellular responses to various stimuli, including stress, calcium ion signaling, and apoptotic pathways. 4. **Interactions with other proteins**: Adducin 1 interacts with a range of proteins, including spectrin, calmodulin, and caspases, to regulate its function and activity. **Pathways and Functions:** 1. **Actin filament organization**: Adducin 1 regulates actin filament organization by binding to actin filaments and modulating their dynamics. 2. **Cytoskeletal dynamics**: The protein is involved in maintaining the stability and organization of the actin cytoskeleton, which is essential for cell movement, intracellular transport, and cell shape. 3. **Apoptosis**: Adducin 1 is involved in apoptotic pathways, where it regulates the cleavage of cellular proteins and the execution of programmed cell death. 4. **Cellular responses to stress**: The protein is also involved in cellular responses to stress, including calcium ion signaling and unfolded protein response (UPR). 5. **Cell adhesion and migration**: Adducin 1 regulates cell adhesion and migration by interacting with cadherins and other adhesion molecules. **Clinical Significance:** Adducin 1 dysfunction has been implicated in various diseases, including: 1. **Cardiac disorders**: Mutations in the ADD1 gene have been associated with cardiac disorders, such as cardiomyopathy and arrhythmias. 2. **Neurological disorders**: Adducin 1 dysfunction has been linked to neurological disorders, including Alzheimer's disease and Parkinson's disease. 3. **Cancer**: The protein's role in regulating cell adhesion and migration makes it a potential target for cancer therapy. 4. **Retinal disorders**: Adducin 1 dysfunction has been implicated in retinal disorders, including retinitis pigmentosa and age-related macular degeneration. In conclusion, Adducin 1 is a critical regulator of actin filament dynamics and cellular processes. Its dysfunction has been implicated in various diseases, highlighting the importance of this protein in maintaining cellular integrity and function. Further research is needed to fully understand the role of Adducin 1 in human health and disease.

Genular Protein ID: 3457601786

Symbol: ADDA_HUMAN

Name: Alpha-adducin

UniProtKB Accession Codes:

P35611 A2A3N8 A2A3P0 B4DI79 D3DVR3 D3DVR4 D3DVR5 Q13734 Q14729 Q16156 Q86XM2 Q9UJB6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 41 Ensembl 6 ExpressionAtlas 1 GO 28 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 3 RefSeq 12 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1840603

Title: Primary structure and domain organization of human alpha and beta adducin.

PubMed ID: 1840603

DOI: 10.1083/jcb.115.3.665

PubMed ID: 1284592

Title: Cloning and mapping of the alpha-adducin gene close to D4S95 and assessment of its relationship to Huntington disease.

PubMed ID: 1284592

DOI: 10.1093/hmg/1.9.669

PubMed ID: 7774961

Title: Genomic organization of the human alpha-adducin gene and its alternately spliced isoforms.

PubMed ID: 7774961

DOI: 10.1016/0888-7543(95)80113-z

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1345173

Title: Cloning of the alpha-adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplification.

PubMed ID: 1345173

DOI: 10.1038/ng1192-223

PubMed ID: 8810272

Title: Adducin regulation. Definition of the calmodulin-binding domain and sites of phosphorylation by protein kinases A and C.

PubMed ID: 8810272

DOI: 10.1074/jbc.271.41.25157

PubMed ID: 10209029

Title: Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility.

PubMed ID: 10209029

DOI: 10.1083/jcb.145.2.347

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 9674650

Title: Human alpha-adducin gene, blood pressure, and sodium metabolism.

PubMed ID: 9674650

DOI: 10.1161/01.hyp.32.1.138

PubMed ID: 10391210

Title: Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis.

PubMed ID: 10391210

DOI: 10.1038/10297

Sequence Information:

  • Length: 737
  • Mass: 80955
  • Checksum: DF13AB30B12F20B6
  • Sequence:
    • MNGDSRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN MMEQKKRVSM 
ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTT NVPNVYPAAP QGGMAALNMS 
LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA AFYRLADLFG WSQLIYNHIT TRVNSEQEHF 
LIVPFGLLYS EVTASSLVKI NLQGDIVDRG STNLGVNQAG FTLHSAIYAA RPDVKCVVHI 
HTPAGAAVSA MKCGLLPISP EALSLGEVAY HDYHGILVDE EEKVLIQKNL GPKSKVLILR 
NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLNPEKYK AKSRSPGSPV 
GEGTGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL REKSKKYSDV EVPASVTGYS 
FASDGDSGTC SPLRHSFQKQ QREKTRWLNS GRGDEASEEG QNGSSPKSKT KWTKEDGHRT 
STSAVPNLFV PLNTNPKEVQ EMRNKIREQN LQDIKTAGPQ SQVLCGVVMD RSLVQGELVT 
ASKAIIEKEY QPHVIVSTTG PNPFTTLTDR ELEEYRREVE RKQKGSEENL DEAREQKEKS 
PPDQPAVPHP PPSTPIKLEE DLVPEPTTGD DSDAATFKPT LPDLSPDEPS EALGFPMLEK 
EEEAHRPPSP TEAPTEASPE PAPDPAPVAE EAAPSAVEEG AAADPGSDGS PGKSPSKKKK 
KFRTPSFLKK SKKKSDS

Genular Protein ID: 1858454274

Symbol: A0A804HL01_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HL01

Database IDs:

ARBA 2 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 16 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MANE-Select 1 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 3 SAM 1 SMART 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 799
  • Mass: 87700
  • Checksum: 30E40C295B5F2E83
  • Sequence:
    • MNGDSRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN MMEQKKRVSM 
ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTT NVPNVYPAAP QGGMAALNMS 
LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA AFYRLADLFG WSQLIYNHIT TRVNSEQEHF 
LIVPFGLLYS EVTASSLVKI NLQGDIVDRG STNLGVNQAG FTLHSAIYAA RPDVKCVVHI 
HTPAGAAVSA MKCGLLPISP EALSLGEVAY HDYHGILVDE EEKVLIQKNL GPKSKVLILR 
NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLNPEKYK AKSRSPGSPV 
GEGTGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL REKSKKYSDV EVPASVTGYS 
FASDGDSGTC SPLRHSFQKQ QREKTRWLNS GRGDEASEEG QNGSSPKSKT KVWTNITHDH 
VKPLLQSLSS GVCVPSCITN CLWTKEDGHR TSTSAVPNLF VPLNTNPKEV QEMRNKIREQ 
NLQDIKTAGP QSQVLCGVVM DRSLVQDAPL SDCTETIEGL ELTEQTFSPA KSLSFRKGEL 
VTASKAIIEK EYQPHVIVST TGPNPFTTLT DRELEEYRRE VERKQKGSEE NLDEAREQKE 
KSPPDQPAVP HPPPSTPIKL EEDLVPEPTT GDDSDAATFK PTLPDLSPDE PSEALGFPML 
EKEEEAHRPP SPTEAPTEAS PEPAPDPAPV AEEAAPSAVE EGAAADPGSD GSPGKSPSKK 
KKKFRTPSFL KKSKKKSDS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.