Genular: Defining Cellular Identity and Function

Details for: Apoa1

Gene ID: 11806

Symbol: Apoa1

Ensembl ID: ENSMUSG00000032083

Description: apolipoprotein A-I

Associated with

Abc-family proteins mediated transport
(R-MMU-382556)
Abc transporters in lipid homeostasis
(R-MMU-1369062)
Binding and uptake of ligands by scavenger receptors
(R-MMU-2173782)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Chylomicron assembly
(R-MMU-8963888)
Chylomicron remodeling
(R-MMU-8963901)
Hdl assembly
(R-MMU-8963896)
Hdl clearance
(R-MMU-8964011)
Hdl remodeling
(R-MMU-8964058)
Heme signaling
(R-MMU-9707616)
Hemostasis
(R-MMU-109582)
Metabolism
(R-MMU-1430728)
Metabolism of fat-soluble vitamins
(R-MMU-6806667)
Metabolism of proteins
(R-MMU-392499)
Metabolism of vitamins and cofactors
(R-MMU-196854)
Plasma lipoprotein assembly
(R-MMU-8963898)
Plasma lipoprotein assembly, remodeling, and clearance
(R-MMU-174824)
Plasma lipoprotein clearance
(R-MMU-8964043)
Plasma lipoprotein remodeling
(R-MMU-8963899)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Retinoid metabolism and transport
(R-MMU-975634)
Scavenging by class a receptors
(R-MMU-3000480)
Scavenging by class b receptors
(R-MMU-3000471)
Scavenging of heme from plasma
(R-MMU-2168880)
Sensory perception
(R-MMU-9709957)
Transport of small molecules
(R-MMU-382551)
Vesicle-mediated transport
(R-MMU-5653656)
Visual phototransduction
(R-MMU-2187338)
Adrenal gland development
(GO:0030325)
Amyloid-beta binding
(GO:0001540)
Animal organ regeneration
(GO:0031100)
Apolipoprotein a-i receptor binding
(GO:0034191)
Apolipoprotein receptor binding
(GO:0034190)
Axon regeneration
(GO:0031103)
Chemorepellent activity
(GO:0045499)
Cholesterol binding
(GO:0015485)
Cholesterol biosynthetic process
(GO:0006695)
Cholesterol efflux
(GO:0033344)
Cholesterol metabolic process
(GO:0008203)
Cholesterol transfer activity
(GO:0120020)
Cholesterol transport
(GO:0030301)
Endothelial cell proliferation
(GO:0001935)
Enzyme binding
(GO:0019899)
Glucocorticoid metabolic process
(GO:0008211)
G protein-coupled receptor signaling pathway
(GO:0007186)
Heat shock protein binding
(GO:0031072)
High-density lipoprotein particle assembly
(GO:0034380)
High-density lipoprotein particle binding
(GO:0008035)
High-density lipoprotein particle receptor binding
(GO:0070653)
High-density lipoprotein particle remodeling
(GO:0034375)
Identical protein binding
(GO:0042802)
Integrin-mediated signaling pathway
(GO:0007229)
Lipase inhibitor activity
(GO:0055102)
Lipid binding
(GO:0008289)
Lipid metabolic process
(GO:0006629)
Lipid storage
(GO:0019915)
Lipid transport
(GO:0006869)
Lipid transporter activity
(GO:0005319)
Lipoprotein biosynthetic process
(GO:0042158)
Lipoprotein metabolic process
(GO:0042157)
Lipoprotein particle binding
(GO:0071813)
Negative regulation of cytokine production involved in immune response
(GO:0002719)
Negative regulation of heterotypic cell-cell adhesion
(GO:0034115)
Negative regulation of interleukin-1 beta production
(GO:0032691)
Negative regulation of tumor necrosis factor-mediated signaling pathway
(GO:0010804)
Negative regulation of very-low-density lipoprotein particle remodeling
(GO:0010903)
Peptidyl-methionine modification
(GO:0018206)
Phosphatidylcholine-sterol o-acyltransferase activator activity
(GO:0060228)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phospholipid binding
(GO:0005543)
Phospholipid efflux
(GO:0033700)
Phospholipid metabolic process
(GO:0006644)
Phospholipid transport
(GO:0015914)
Positive regulation of cholesterol efflux
(GO:0010875)
Positive regulation of rho protein signal transduction
(GO:0035025)
Protein binding
(GO:0005515)
Protein localization
(GO:0008104)
Protein oxidation
(GO:0018158)
Regulation of cdc42 protein signal transduction
(GO:0032489)
Regulation of intestinal cholesterol absorption
(GO:0030300)
Regulation of protein phosphorylation
(GO:0001932)
Signaling receptor binding
(GO:0005102)
Steroid metabolic process
(GO:0008202)

Other Information

Proteins

Apolipoprotein A-I

Genular Protein ID: 1832266644

Symbol: APOA1_MOUSE

Name: Apolipoprotein A-I

UniProtKB Accession Codes:

Q00623 O08855 O09042 Q8BPD5

Database IDs:

Citations:

PubMed ID: 1596360

Title: Mouse apolipoprotein AI. cDNA-derived primary structure, gene organisation and complete nucleotide sequence.

PubMed ID: 1596360

DOI: 10.1515/bchm3.1992.373.1.187

PubMed ID: 1478650

Title: Characterization of the mouse apolipoprotein Apoa-1/Apoc-3 gene locus: genomic, mRNA, and protein sequences with comparisons to other species.

PubMed ID: 1478650

DOI: 10.1016/s0888-7543(05)80133-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16876491

Title: Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.

PubMed ID: 16876491

DOI: 10.1016/j.bbapap.2006.06.001

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 264
Mass: 30616
Checksum: 5E33FF201963583B
Sequence:

MKAVVLAVAL VFLTGSQAWH VWQQDEPQSQ WDKVKDFANV YVDAVKDSGR DYVSQFESSS 
LGQQLNLNLL ENWDTLGSTV SQLQERLGPL TRDFWDNLEK ETDWVRQEMN KDLEEVKQKV 
QPYLDEFQKK WKEDVELYRQ KVAPLGAELQ ESARQKLQEL QGRLSPVAEE FRDRMRTHVD 
SLRTQLAPHS EQMRESLAQR LAELKSNPTL NEYHTRAKTH LKTLGEKARP ALEDLRHSLM 
PMLETLKTQV QSVIDKASET LTAQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Apoa1

Associated with

Other Information

Mouse apolipoprotein AI. cDNA-derived primary structure, gene organisation and complete nucleotide sequence. PubMed ID: 1596360

Characterization of the mouse apolipoprotein Apoa-1/Apoc-3 gene locus: genomic, mRNA, and protein sequences with comparisons to other species. PubMed ID: 1478650

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications. PubMed ID: 16876491

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079