Apoa2 | ENSMUSG00000005681 | NCBI 11807

Details for: Apoa2

Gene ID: 11807

Symbol: Apoa2

Ensembl ID: ENSMUSG00000005681

Description: apolipoprotein A-II

Associated with

Chylomicron assembly
(R-MMU-8963888)
Chylomicron remodeling
(R-MMU-8963901)
Metabolism
(R-MMU-1430728)
Metabolism of fat-soluble vitamins
(R-MMU-6806667)
Metabolism of proteins
(R-MMU-392499)
Metabolism of vitamins and cofactors
(R-MMU-196854)
Plasma lipoprotein assembly
(R-MMU-8963898)
Plasma lipoprotein assembly, remodeling, and clearance
(R-MMU-174824)
Plasma lipoprotein remodeling
(R-MMU-8963899)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Retinoid metabolism and transport
(R-MMU-975634)
Sensory perception
(R-MMU-9709957)
Transport of small molecules
(R-MMU-382551)
Visual phototransduction
(R-MMU-2187338)
Animal organ regeneration
(GO:0031100)
Apolipoprotein receptor binding
(GO:0034190)
Cholesterol binding
(GO:0015485)
Cholesterol efflux
(GO:0033344)
Cholesterol homeostasis
(GO:0042632)
Cholesterol metabolic process
(GO:0008203)
Cholesterol transfer activity
(GO:0120020)
Cholesterol transport
(GO:0030301)
Chylomicron
(GO:0042627)
Cytosol
(GO:0005829)
Diacylglycerol catabolic process
(GO:0046340)
Enzyme binding
(GO:0019899)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Heat shock protein binding
(GO:0031072)
High-density lipoprotein particle
(GO:0034364)
High-density lipoprotein particle assembly
(GO:0034380)
High-density lipoprotein particle binding
(GO:0008035)
High-density lipoprotein particle clearance
(GO:0034384)
High-density lipoprotein particle receptor binding
(GO:0070653)
High-density lipoprotein particle remodeling
(GO:0034375)
Lipase inhibitor activity
(GO:0055102)
Lipid binding
(GO:0008289)
Lipid transport
(GO:0006869)
Lipid transporter activity
(GO:0005319)
Lipoprotein metabolic process
(GO:0042157)
Low-density lipoprotein particle remodeling
(GO:0034374)
Negative regulation of cholesterol import
(GO:0060621)
Negative regulation of cholesterol transport
(GO:0032375)
Negative regulation of cholesterol transporter activity
(GO:0060695)
Negative regulation of cytokine production involved in immune response
(GO:0002719)
Negative regulation of lipase activity
(GO:0060192)
Negative regulation of lipid catabolic process
(GO:0050995)
Negative regulation of very-low-density lipoprotein particle remodeling
(GO:0010903)
Peptidyl-methionine modification
(GO:0018206)
Phosphatidylcholine-sterol o-acyltransferase activator activity
(GO:0060228)
Phosphatidylcholine binding
(GO:0031210)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phospholipid binding
(GO:0005543)
Phospholipid catabolic process
(GO:0009395)
Phospholipid efflux
(GO:0033700)
Positive regulation of coa-transferase activity
(GO:1905920)
Positive regulation of interleukin-8 production
(GO:0032757)
Positive regulation of lipid catabolic process
(GO:0050996)
Positive regulation of phagocytosis
(GO:0050766)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Protein oxidation
(GO:0018158)
Protein stabilization
(GO:0050821)
Regulation of intestinal cholesterol absorption
(GO:0030300)
Regulation of protein stability
(GO:0031647)
Response to glucose
(GO:0009749)
Reverse cholesterol transport
(GO:0043691)
Signaling receptor binding
(GO:0005102)
Spherical high-density lipoprotein particle
(GO:0034366)
Triglyceride-rich lipoprotein particle remodeling
(GO:0034370)
Very-low-density lipoprotein particle
(GO:0034361)

Other Information

Proteins

Apolipoprotein A-II

Genular Protein ID: 2203446572

Symbol: APOA2_MOUSE

Name: Apolipoprotein A-II

UniProtKB Accession Codes:

P09813 Q3UKX6 Q61317

Database IDs:

Citations:

PubMed ID: 2426658

Title: Molecular cloning and nucleotide sequence of cDNA for murine senile amyloid protein: nucleotide substitutions found in apolipoprotein A-II cDNA of senescence accelerated mouse (SAM).

PubMed ID: 2426658

DOI: 10.1093/nar/14.14.5729

PubMed ID: 2514123

Title: Structural organization of the gene encoding apolipoprotein A-II in an amyloidotic strain of senescence-accelerated mouse.

PubMed ID: 2514123

DOI: 10.1016/0378-1119(89)90154-6

PubMed ID: 2118905

Title: A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition.

PubMed ID: 2118905

DOI: 10.1016/s0021-9258(17)46234-x

PubMed ID: 1683229

Title: Polymorphism of apolipoprotein A-II (apoA-II) among inbred strains of mice. Relationship between the molecular type of apoA-II and mouse senile amyloidosis.

PubMed ID: 1683229

DOI: 10.1042/bj2790427

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3095143

Title: The single proline-glutamine substitution at position 5 enhances the potency of amyloid fibril formation of murine apo A-II.

PubMed ID: 3095143

DOI: 10.1016/0014-5793(86)80006-0

PubMed ID: 3089836

Title: High homology is present in the primary structures between murine senile amyloid protein (ASSAM) and human apolipoprotein A-II.

PubMed ID: 3089836

DOI: 10.1016/0014-5793(86)80732-3

PubMed ID: 16876491

Title: Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.

PubMed ID: 16876491

DOI: 10.1016/j.bbapap.2006.06.001

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 102
Mass: 11309
Checksum: F50142E0D118665B
Sequence:

MKLLAMVALL VTICSLEGAL VKRQADGPDM QSLFTQYFQS MTDYGKDLME KAKTSEIQSQ 
AKAYFEKTHE QLTPLVRSAG TSLVNFFSSL MNLEEKPAPA AK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Apoa2

Associated with

Other Information

Molecular cloning and nucleotide sequence of cDNA for murine senile amyloid protein: nucleotide substitutions found in apolipoprotein A-II cDNA of senescence accelerated mouse (SAM). PubMed ID: 2426658

Structural organization of the gene encoding apolipoprotein A-II in an amyloidotic strain of senescence-accelerated mouse. PubMed ID: 2514123

A polymorphism affecting apolipoprotein A-II translational efficiency determines high density lipoprotein size and composition. PubMed ID: 2118905

Polymorphism of apolipoprotein A-II (apoA-II) among inbred strains of mice. Relationship between the molecular type of apoA-II and mouse senile amyloidosis. PubMed ID: 1683229

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The single proline-glutamine substitution at position 5 enhances the potency of amyloid fibril formation of murine apo A-II. PubMed ID: 3095143

High homology is present in the primary structures between murine senile amyloid protein (ASSAM) and human apolipoprotein A-II. PubMed ID: 3089836

Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications. PubMed ID: 16876491

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079