Details for: Aqp2

Gene ID: 11827

Symbol: Aqp2

Ensembl ID: ENSMUSG00000023013

Description: aquaporin 2

Associated with

Other Information

Genular Protein ID: 4192620941

Symbol: AQP2_MOUSE

Name: Aquaporin-2

UniProtKB Accession Codes:

P56402 Q8VCG5 Q9R232

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 35 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SAM 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10191086

Title: cDNA and genomic cloning of mouse aquaporin-2: functional analysis of an orthologous mutant causing nephrogenic diabetes insipidus.

PubMed ID: 10191086

DOI: 10.1006/geno.1999.5759

PubMed ID: 12426236

Title: Renal principal cell-specific expression of green fluorescent protein in transgenic mice.

PubMed ID: 12426236

DOI: 10.1152/ajprenal.0224.2001

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16735444

Title: Loss of calcineurin Aalpha results in altered trafficking of AQP2 and in nephrogenic diabetes insipidus.

PubMed ID: 16735444

DOI: 10.1242/jcs.02971

PubMed ID: 16641094

Title: Congenital progressive hydronephrosis (cph) is caused by an S256L mutation in aquaporin-2 that affects its phosphorylation and apical membrane accumulation.

PubMed ID: 16641094

DOI: 10.1073/pnas.0602087103

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 31605441

Title: Identification and classification of epithelial cells in nephron segments by actin cytoskeleton patterns.

PubMed ID: 31605441

DOI: 10.1111/febs.15088

Sequence Information:

  • Length: 271
  • Mass: 28965
  • Checksum: 41601C37BFD11CBA
  • Sequence:
    • MWELRSIAFS RAVLAEFLAT LLFVFFGLGS ALQWASSPPS VLQIAVAFGL GIGTLVQALG 
HVSGAHINPA VTVACLVGCH VSFLRAAFYV AAQLLGAVAG AAILHEITPV EIRGDLAVNA 
LHNNATAGQA VTVELFLTMQ LVLCIFASTD ERRSDNLGSP ALSIGFSVTL GHLLGIYFTG 
CSMNPARSLA PAVVTGKFDD HWVFWIGPLV GAVIGSLLYN YLLFPSTKSL QERLAVLKGL 
EPDTDWEERE VRRRQSVELH SPQSLPRGSK A

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.