Genular: Defining Cellular Identity and Function

Details for: Areg

Gene ID: 11839

Symbol: Areg

Ensembl ID: ENSMUSG00000029378

Description: amphiregulin

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Cargo concentration in the er
(R-MMU-5694530)
Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Copii-mediated vesicle transport
(R-MMU-204005)
Egfr downregulation
(R-MMU-182971)
Egfr interacts with phospholipase c-gamma
(R-MMU-212718)
Er to golgi anterograde transport
(R-MMU-199977)
Esr-mediated signaling
(R-MMU-8939211)
Extra-nuclear estrogen signaling
(R-MMU-9009391)
Gab1 signalosome
(R-MMU-180292)
Grb2 events in egfr signaling
(R-MMU-179812)
Intracellular signaling by second messengers
(R-MMU-9006925)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Post-translational protein modification
(R-MMU-597592)
Raf/map kinase cascade
(R-MMU-5673001)
Shc1 events in egfr signaling
(R-MMU-180336)
Signaling by egfr
(R-MMU-177929)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Vesicle-mediated transport
(R-MMU-5653656)
Cell surface
(GO:0009986)
Cytokine activity
(GO:0005125)
Cytoplasm
(GO:0005737)
Dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
(GO:0060598)
Epidermal growth factor receptor binding
(GO:0005154)
Epidermal growth factor receptor signaling pathway
(GO:0007173)
Epithelial cell proliferation involved in mammary gland duct elongation
(GO:0060750)
Erbb2-egfr signaling pathway
(GO:0038134)
Extracellular space
(GO:0005615)
Glial cell proliferation
(GO:0014009)
G protein-coupled receptor signaling pathway
(GO:0007186)
Growth factor activity
(GO:0008083)
Intracellular anatomical structure
(GO:0005622)
Mammary gland alveolus development
(GO:0060749)
Mammary gland branching involved in thelarche
(GO:0060744)
Membrane
(GO:0016020)
Negative regulation of osteoblast differentiation
(GO:0045668)
Neuron projection development
(GO:0031175)
Nucleus
(GO:0005634)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of phosphorylation
(GO:0042327)
Receptor ligand activity
(GO:0048018)
Response to estradiol
(GO:0032355)
Response to glucocorticoid
(GO:0051384)
Transmembrane receptor protein tyrosine kinase activator activity
(GO:0030297)

Other Information

Proteins

Amphiregulin

Genular Protein ID: 1011504318

Symbol: AREG_MOUSE

Name: Amphiregulin

UniProtKB Accession Codes:

P31955

Database IDs:

Citations:

PubMed ID: 1318038

Title: Androgen-responsive expression and mitogenic activity of schwannoma-derived growth factor on an androgen-dependent Shionogi mouse mammary carcinoma cell line.

PubMed ID: 1318038

DOI: 10.1016/s0006-291x(05)80961-1

PubMed ID: 8592515

Title: Amphiregulin is an implantation-specific and progesterone-regulated gene in the mouse uterus.

PubMed ID: 8592515

DOI: 10.1210/mend.9.6.8592515

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 248
Mass: 27549
Checksum: 98C61A1B0E75A64E
Sequence:

MRTPLLPLAR SVLLLLVLGS GHYAAALELN DPSSGKGESL SGDHSAGGLE LSVGREVSTI 
SEMPSGSELS TGDYDYSEEY DNEPQISGYI IDDSVRVEQV IKPKKNKTEG EKSTEKPKRK 
KKGGKNGKGR RNKKKKNPCT AKFQNFCIHG ECRYIENLEV VTCNCHQDYF GERCGEKSMK 
THSEDDKDLS KIAVVAVTIF VSAIILAAIG IGIVITVHLW KRYFREYEGE TEERRRLRQE 
NGTVHAIA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Areg

Associated with

Other Information

Androgen-responsive expression and mitogenic activity of schwannoma-derived growth factor on an androgen-dependent Shionogi mouse mammary carcinoma cell line. PubMed ID: 1318038

Amphiregulin is an implantation-specific and progesterone-regulated gene in the mouse uterus. PubMed ID: 8592515

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 1318038

PubMed ID: 8592515

PubMed ID: 16141072

PubMed ID: 15489334