Genular: Defining Cellular Identity and Function

Details for: Arf1

Gene ID: 11840

Symbol: Arf1

Ensembl ID: ENSMUSG00000048076

Description: ADP-ribosylation factor 1

Associated with

Adaptive immune system
(R-MMU-1280218)
Asparagine n-linked glycosylation
(R-MMU-446203)
Copi-dependent golgi-to-er retrograde traffic
(R-MMU-6811434)
Copi-mediated anterograde transport
(R-MMU-6807878)
Er to golgi anterograde transport
(R-MMU-199977)
Glycosphingolipid transport
(R-MMU-9845576)
Golgi-to-er retrograde transport
(R-MMU-8856688)
Golgi associated vesicle biogenesis
(R-MMU-432722)
Immune system
(R-MMU-168256)
Intra-golgi and retrograde golgi-to-er traffic
(R-MMU-6811442)
Intra-golgi traffic
(R-MMU-6811438)
Lysosome vesicle biogenesis
(R-MMU-432720)
Membrane trafficking
(R-MMU-199991)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of proteins
(R-MMU-392499)
Mhc class ii antigen presentation
(R-MMU-2132295)
Phospholipid metabolism
(R-MMU-1483257)
Pi metabolism
(R-MMU-1483255)
Post-translational protein modification
(R-MMU-597592)
Synthesis of pips at the golgi membrane
(R-MMU-1660514)
Synthesis of pips at the plasma membrane
(R-MMU-1660499)
Trans-golgi network vesicle budding
(R-MMU-199992)
Transport of small molecules
(R-MMU-382551)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Actin filament organization
(GO:0007015)
Cell leading edge
(GO:0031252)
Cellular response to virus
(GO:0098586)
Copi-coated vesicle
(GO:0030137)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendritic spine organization
(GO:0097061)
Endomembrane system
(GO:0012505)
Gdp binding
(GO:0019003)
Glutamatergic synapse
(GO:0098978)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Golgi to transport vesicle transport
(GO:0055108)
G protein activity
(GO:0003925)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Intracellular copper ion homeostasis
(GO:0006878)
Intracellular protein transport
(GO:0006886)
Late endosome
(GO:0005770)
Long-term synaptic depression
(GO:0060292)
Lysosomal membrane organization
(GO:0097212)
Magnesium ion binding
(GO:0000287)
Membrane
(GO:0016020)
Mitotic cleavage furrow ingression
(GO:1990386)
Neuron projection
(GO:0043005)
Nucleotide binding
(GO:0000166)
Peroxisomal membrane
(GO:0005778)
Phospholipase d activator activity
(GO:1990583)
Plasma membrane
(GO:0005886)
Positive regulation of calcium ion-dependent exocytosis
(GO:0045956)
Positive regulation of dendritic spine development
(GO:0060999)
Positive regulation of endocytosis
(GO:0045807)
Positive regulation of er to golgi vesicle-mediated transport
(GO:1902953)
Positive regulation of late endosome to lysosome transport
(GO:1902824)
Positive regulation of protein secretion
(GO:0050714)
Positive regulation of sodium ion transmembrane transport
(GO:1902307)
Postsynaptic actin cytoskeleton organization
(GO:0098974)
Postsynaptic density
(GO:0014069)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein transport
(GO:0015031)
Regulation of arp2/3 complex-mediated actin nucleation
(GO:0034315)
Regulation of phospholipid metabolic process
(GO:1903725)
Regulation of receptor internalization
(GO:0002090)
Sarcomere
(GO:0030017)
Synapse
(GO:0045202)
Synaptic vesicle budding
(GO:0070142)
Trans-golgi network
(GO:0005802)
Very-low-density lipoprotein particle assembly
(GO:0034379)
Vesicle-mediated transport
(GO:0016192)

Other Information

Proteins

ADP-ribosylation factor 1

Genular Protein ID: 125922250

Symbol: ARF1_MOUSE

Name: ADP-ribosylation factor 1

UniProtKB Accession Codes:

P84078 P10947 P32889 Q3THZ2 Q3U849 Q3UDG1 Q3UF76

Database IDs:

Citations:

PubMed ID: 8947846

Title: Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).

PubMed ID: 8947846

DOI: 10.1093/oxfordjournals.jbchem.a021484

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11950392

Title: GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.

PubMed ID: 11950392

DOI: 10.1042/bj20020428

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27723745

Title: C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.

PubMed ID: 27723745

DOI: 10.1038/nn.4407

PubMed ID: 36566324

Title: Arf1 facilitates mast cell proliferation via the mTORC1 pathway.

PubMed ID: 36566324

DOI: 10.1038/s41598-022-26925-1

PubMed ID: 37392777

Title: ARF1 maintains intestinal homeostasis by modulating gut microbiota and stem cell function.

PubMed ID: 37392777

DOI: 10.1016/j.lfs.2023.121902

PubMed ID: 12679809

Title: Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport.

PubMed ID: 12679809

DOI: 10.1038/nsb920

PubMed ID: 17347647

Title: Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes.

PubMed ID: 17347647

DOI: 10.1038/sj.emboj.7601634

Sequence Information:

Length: 181
Mass: 20697
Checksum: AAC773D4A60186B6
Sequence:

MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTILYKLKLG EIVTTIPTIG FNVETVEYKN 
ISFTVWDVGG QDKIRPLWRH YFQNTQGLIF VVDSNDRERV NEAREELMRM LAEDELRDAV 
LLVFANKQDL PNAMNAAEIT DKLGLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ 
K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Arf1

Associated with

Other Information

Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6). PubMed ID: 8947846

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors. PubMed ID: 11950392

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. PubMed ID: 27723745

Arf1 facilitates mast cell proliferation via the mTORC1 pathway. PubMed ID: 36566324

ARF1 maintains intestinal homeostasis by modulating gut microbiota and stem cell function. PubMed ID: 37392777

Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport. PubMed ID: 12679809

Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes. PubMed ID: 17347647