Details for: CLCN7

Gene ID: 1186

Symbol: CLCN7

Ensembl ID: ENSG00000103249

Description: chloride voltage-gated channel 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 143.3667
    Cell Significance Index: -22.3000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 86.5585
    Cell Significance Index: -21.9600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 50.4530
    Cell Significance Index: -23.8200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 44.4803
    Cell Significance Index: -22.8800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.4770
    Cell Significance Index: -20.5100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.1897
    Cell Significance Index: -23.6600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.5708
    Cell Significance Index: -22.9600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.8697
    Cell Significance Index: -21.1000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.0884
    Cell Significance Index: -24.0300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.5332
    Cell Significance Index: -12.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.3717
    Cell Significance Index: 135.7000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.2724
    Cell Significance Index: 17.3600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1316
    Cell Significance Index: 184.0500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.1157
    Cell Significance Index: 29.9000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9367
    Cell Significance Index: 187.9100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6700
    Cell Significance Index: 132.9600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6668
    Cell Significance Index: 72.5300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.5417
    Cell Significance Index: 8.6900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5396
    Cell Significance Index: 15.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5207
    Cell Significance Index: 11.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.5188
    Cell Significance Index: 60.4600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4666
    Cell Significance Index: 30.1100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4452
    Cell Significance Index: 26.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4274
    Cell Significance Index: 153.2900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.4269
    Cell Significance Index: 5.3000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3386
    Cell Significance Index: 23.4200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3107
    Cell Significance Index: 56.0200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3023
    Cell Significance Index: 13.7000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2665
    Cell Significance Index: 7.6400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2429
    Cell Significance Index: 132.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2297
    Cell Significance Index: 10.7100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2212
    Cell Significance Index: 11.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2198
    Cell Significance Index: 11.5400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1906
    Cell Significance Index: 23.4400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1602
    Cell Significance Index: 22.0000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1566
    Cell Significance Index: 4.4700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1562
    Cell Significance Index: 10.5000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1549
    Cell Significance Index: 291.6900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1393
    Cell Significance Index: 61.5900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.1174
    Cell Significance Index: 3.1400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1141
    Cell Significance Index: 78.8900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1120
    Cell Significance Index: 2.8000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1047
    Cell Significance Index: 19.9300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0895
    Cell Significance Index: 6.8700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0781
    Cell Significance Index: 2.2500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0683
    Cell Significance Index: 2.4000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0459
    Cell Significance Index: 5.8900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0366
    Cell Significance Index: 67.4800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0324
    Cell Significance Index: 2.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0296
    Cell Significance Index: 18.7900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0254
    Cell Significance Index: 22.9100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0245
    Cell Significance Index: 4.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0169
    Cell Significance Index: 26.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0007
    Cell Significance Index: 0.3300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0017
    Cell Significance Index: -0.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0026
    Cell Significance Index: -3.4700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0049
    Cell Significance Index: -0.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0107
    Cell Significance Index: -7.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0127
    Cell Significance Index: -1.8400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0159
    Cell Significance Index: -12.0300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0160
    Cell Significance Index: -1.8900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0283
    Cell Significance Index: -20.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0289
    Cell Significance Index: -2.9500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0329
    Cell Significance Index: -0.7000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0384
    Cell Significance Index: -21.6700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0423
    Cell Significance Index: -26.3900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0550
    Cell Significance Index: -7.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0715
    Cell Significance Index: -20.5600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0755
    Cell Significance Index: -3.3400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0838
    Cell Significance Index: -9.6000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0884
    Cell Significance Index: -6.2500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0911
    Cell Significance Index: -1.8900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1004
    Cell Significance Index: -7.4800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1056
    Cell Significance Index: -4.0000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1094
    Cell Significance Index: -6.1400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1147
    Cell Significance Index: -1.9200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1186
    Cell Significance Index: -24.9800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1217
    Cell Significance Index: -2.2500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1357
    Cell Significance Index: -4.7200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1627
    Cell Significance Index: -16.9400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1655
    Cell Significance Index: -10.1700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1980
    Cell Significance Index: -5.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2415
    Cell Significance Index: -7.7400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2455
    Cell Significance Index: -15.0500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2621
    Cell Significance Index: -20.7600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2897
    Cell Significance Index: -7.4000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3023
    Cell Significance Index: -7.9500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.3330
    Cell Significance Index: -4.9900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3393
    Cell Significance Index: -5.8200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3583
    Cell Significance Index: -18.6700
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.3588
    Cell Significance Index: -3.0500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4210
    Cell Significance Index: -12.4000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4311
    Cell Significance Index: -9.1500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4330
    Cell Significance Index: -13.7900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4513
    Cell Significance Index: -14.7800
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.4580
    Cell Significance Index: -3.5300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4722
    Cell Significance Index: -10.3400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4949
    Cell Significance Index: -9.6600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5084
    Cell Significance Index: -17.8100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.5100
    Cell Significance Index: -7.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Clutching function:** CLCN7 is a voltage-gated chloride channel that exhibits a clutching function, allowing it to rapidly switch between open and closed states in response to changes in membrane potential. 2. **High affinity for chloride:** CLCN7 has a high affinity for chloride ions, making it an effective chloride channel for regulating chloride movement across cell membranes. 3. **Regulation of excitability:** CLCN7 is expressed in various neuronal populations, including dopaminergic neurons, and plays a critical role in regulating neuronal excitability and neurotransmission. 4. **Expression in epithelial cells:** CLCN7 is also expressed in epithelial cells, including pigmented epithelial cells and corneal epithelial cells, where it regulates chloride transport and epithelial function. **Pathways and Functions:** 1. **Ion channel transport:** CLCN7 functions as a chloride channel, transporting chloride ions across cell membranes in response to changes in membrane potential. 2. **Regulation of neurotransmission:** CLCN7 is expressed in various neuronal populations and plays a critical role in regulating neurotransmission, particularly in dopaminergic neurons. 3. **Chloride homeostasis:** CLCN7 helps maintain chloride homeostasis in epithelial cells, regulating chloride transport and epithelial function. 4. **Stimuli-sensing channels:** CLCN7 is involved in stimuli-sensing channels, allowing cells to respond to changes in their environment. **Clinical Significance:** 1. **Neurological disorders:** CLCN7 has been implicated in various neurological disorders, including epilepsy, schizophrenia, and autism spectrum disorder. 2. **Developmental disorders:** CLCN7 is also involved in developmental disorders, such as congenital myotonia and Lambert-Eaton myasthenic syndrome. 3. **Epithelial function:** CLCN7 plays a critical role in maintaining epithelial function, particularly in the cornea and gut. 4. **Therapeutic potential:** Targeting CLCN7 may offer therapeutic potential for treating various neurological and developmental disorders. In conclusion, CLCN7 is a critical gene that plays a pivotal role in regulating cellular homeostasis and neurotransmission in various tissues. Dysregulation of CLCN7 has been implicated in various neurological and developmental disorders, highlighting the importance of this gene in maintaining proper cellular function. Further research is needed to fully elucidate the role of CLCN7 in human disease and to explore its therapeutic potential.

Genular Protein ID: 1972890951

Symbol: CLCN7_HUMAN

Name: H(+)/Cl(-) exchange transporter 7

UniProtKB Accession Codes:

P51798 A6NEJ7 A8K5T9 A8K7X1 B3KPN3 E9PDB9 Q9NYX5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 7 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 6 Ensembl 1 ExpressionAtlas 1 GO 10 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8543009

Title: ClC-6 and ClC-7 are two novel broadly expressed members of the CLC chloride channel family.

PubMed ID: 8543009

DOI: 10.1016/0014-5793(95)01298-2

PubMed ID: 9565675

Title: The exon-intron architecture of human chloride channel genes is not conserved.

PubMed ID: 9565675

DOI: 10.1016/s0167-4781(98)00014-1

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17897319

Title: Integral and associated lysosomal membrane proteins.

PubMed ID: 17897319

DOI: 10.1111/j.1600-0854.2007.00643.x

PubMed ID: 18449189

Title: The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.

PubMed ID: 18449189

DOI: 10.1038/nature06907

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21527911

Title: ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity.

PubMed ID: 21527911

DOI: 10.1038/emboj.2011.137

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 11207362

Title: Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man.

PubMed ID: 11207362

DOI: 10.1016/s0092-8674(01)00206-9

PubMed ID: 11741829

Title: Albers-Schonberg disease (autosomal dominant osteopetrosis, type II) results from mutations in the ClCN7 chloride channel gene.

PubMed ID: 11741829

DOI: 10.1093/hmg/10.25.2861

PubMed ID: 14584882

Title: Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis.

PubMed ID: 14584882

DOI: 10.1359/jbmr.2003.18.10.1740

PubMed ID: 17033731

Title: DNA-based diagnosis of malignant osteopetrosis by whole-genome scan using a single-nucleotide polymorphism microarray: standardization of molecular investigations of genetic diseases due to consanguinity.

PubMed ID: 17033731

DOI: 10.1007/s10038-006-0075-4

PubMed ID: 19288050

Title: Identification of the CLCN7 gene mutations in two Chinese families with autosomal dominant osteopetrosis (type II).

PubMed ID: 19288050

DOI: 10.1007/s00774-009-0051-0

PubMed ID: 19953639

Title: Molecular and clinical heterogeneity in CLCN7-dependent osteopetrosis: report of 20 novel mutations.

PubMed ID: 19953639

DOI: 10.1002/humu.21167

PubMed ID: 26395888

Title: Novel mutations of CLCN7 cause autosomal dominant osteopetrosis type II (ADO-II) and intermediate autosomal recessive osteopetrosis (IARO) in Chinese patients.

PubMed ID: 26395888

DOI: 10.1007/s00198-015-3320-x

PubMed ID: 26477479

Title: A novel mutation and a known mutation in the CLCN7 gene associated with relatively stable infantile malignant osteopetrosis in a Chinese patient.

PubMed ID: 26477479

DOI: 10.1016/j.gene.2015.10.021

PubMed ID: 31155284

Title: Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification.

PubMed ID: 31155284

DOI: 10.1016/j.ajhg.2019.04.008

Sequence Information:

  • Length: 805
  • Mass: 88679
  • Checksum: E56BC0B4ADE1C695
  • Sequence:
    • MANVSKKVSW SGRDRDDEEA APLLRRTARP GGGTPLLNGA GPGAARQSPR SALFRVGHMS 
SVELDDELLD PDMDPPHPFP KEIPHNEKLL SLKYESLDYD NSENQLFLEE ERRINHTAFR 
TVEIKRWVIC ALIGILTGLV ACFIDIVVEN LAGLKYRVIK GNIDKFTEKG GLSFSLLLWA 
TLNAAFVLVG SVIVAFIEPV AAGSGIPQIK CFLNGVKIPH VVRLKTLVIK VSGVILSVVG 
GLAVGKEGPM IHSGSVIAAG ISQGRSTSLK RDFKIFEYFR RDTEKRDFVS AGAAAGVSAA 
FGAPVGGVLF SLEEGASFWN QFLTWRIFFA SMISTFTLNF VLSIYHGNMW DLSSPGLINF 
GRFDSEKMAY TIHEIPVFIA MGVVGGVLGA VFNALNYWLT MFRIRYIHRP CLQVIEAVLV 
AAVTATVAFV LIYSSRDCQP LQGGSMSYPL QLFCADGEYN SMAAAFFNTP EKSVVSLFHD 
PPGSYNPLTL GLFTLVYFFL ACWTYGLTVS AGVFIPSLLI GAAWGRLFGI SLSYLTGAAI 
WADPGKYALM GAAAQLGGIV RMTLSLTVIM MEATSNVTYG FPIMLVLMTA KIVGDVFIEG 
LYDMHIQLQS VPFLHWEAPV TSHSLTAREV MSTPVTCLRR REKVGVIVDV LSDTASNHNG 
FPVVEHADDT QPARLQGLIL RSQLIVLLKH KVFVERSNLG LVQRRLRLKD FRDAYPRFPP 
IQSIHVSQDE RECTMDLSEF MNPSPYTVPQ EASLPRVFKL FRALGLRHLV VVDNRNQVVG 
LVTRKDLARY RLGKRGLEEL SLAQT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.