Genular: Defining Cellular Identity and Function

Details for: Arnt

Gene ID: 11863

Symbol: Arnt

Ensembl ID: ENSMUSG00000015522

Description: aryl hydrocarbon receptor nuclear translocator

Associated with

Aryl hydrocarbon receptor signalling
(R-MMU-8937144)
Biological oxidations
(R-MMU-211859)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to hypoxia
(R-MMU-1234174)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Endogenous sterols
(R-MMU-211976)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism
(R-MMU-1430728)
Npas4 regulates expression of target genes
(R-MMU-9768919)
Phase i - functionalization of compounds
(R-MMU-211945)
Regulation of gene expression by hypoxia-inducible factor
(R-MMU-1234158)
Rna polymerase ii transcription
(R-MMU-73857)
Transcriptional regulation by npas4
(R-MMU-9634815)
Xenobiotics
(R-MMU-211981)
Aryl hydrocarbon receptor binding
(GO:0017162)
Aryl hydrocarbon receptor complex
(GO:0034751)
Cell differentiation
(GO:0030154)
Cellular response to oxidative stress
(GO:0034599)
Cis-regulatory region sequence-specific dna binding
(GO:0000987)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Embryonic placenta development
(GO:0001892)
Negative regulation of inflammatory response
(GO:0050728)
Nuclear aryl hydrocarbon receptor complex
(GO:0034753)
Nuclear body
(GO:0016604)
Nuclear receptor activity
(GO:0004879)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of hormone biosynthetic process
(GO:0046886)
Positive regulation of protein sumoylation
(GO:0033235)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to hypoxia
(GO:0001666)
Response to toxic substance
(GO:0009636)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Aryl hydrocarbon receptor nuclear translocator
Q3ULM2_MOUSE

Genular Protein ID: 1544878300

Symbol: ARNT_MOUSE

Name: Aryl hydrocarbon receptor nuclear translocator

UniProtKB Accession Codes:

P53762 Q60661 Q921F3

Database IDs:

Citations:

PubMed ID: 8065341

Title: Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT).

PubMed ID: 8065341

DOI: 10.1128/mcb.14.9.6075-6086.1994

PubMed ID: 7961746

Title: Transcriptional activation function of the mouse Ah receptor nuclear translocator.

PubMed ID: 7961746

DOI: 10.1016/s0021-9258(18)46900-1

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9887096

Title: Identification of a novel mechanism of regulation of Ah (dioxin) receptor function.

PubMed ID: 9887096

DOI: 10.1101/gad.13.1.20

PubMed ID: 11025203

Title: Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development.

PubMed ID: 11025203

DOI: 10.1016/s0925-4773(00)00415-9

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24001774

Title: Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain.

PubMed ID: 24001774

DOI: 10.1128/mcb.00698-13

PubMed ID: 26245371

Title: Structural integration in hypoxia-inducible factors.

PubMed ID: 26245371

DOI: 10.1038/nature14883

PubMed ID: 27782878

Title: NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.

PubMed ID: 27782878

DOI: 10.7554/elife.18790

PubMed ID: 28602820

Title: Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation.

PubMed ID: 28602820

DOI: 10.1016/j.str.2017.05.008

Sequence Information:

Length: 791
Mass: 86963
Checksum: BDEC0991CD57D402
Sequence:

MAATTANPEM TSDVPSLGPT IASGNPGPGI QGGGAVVQRA IKRRSGLDFD DEVEVNTKFL 
RCDDDQMCND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS 
ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS 
CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRVLDLK 
TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG TSSVDPVSMN RLSFLRNRCR NGLGSVKEGE 
PHFVVVHCTG YIKAWPPAGV SLPDDDPEAG QGSKFCLVAI GRLQVTSSPN CTDMSNICQP 
TEFISRHNIE GIFTFVDHRC VATVGYQPQE LLGKNIVEFC HPEDQQLLRD SFQQVVKLKG 
QVLSVMFRFR SKTREWLWMR TSSFTFQNPY SDEIEYIICT NTNVKNSSQE PRPTLSNTIP 
RSQLGPTANL SLEMGTGQLP SRQQQQQHTE LDMVPGRDGL ASYNHSQVSV QPVASAGSEH 
SKPLEKSEGL FAQDRDPRFP EIYPSITADQ SKGISSSTVP ATQQLFSQGS SFPPNPRPAE 
NFRNSGLTPP VTIVQPSSSA GQILAQISRH SNPAQGSAPT WTSSSRPGFA AQQVPTQATA 
KTRSSQFGVN NFQTSSSFSA MSLPGAPTAS SGTAAYPALP NRGSNFPPET GQTTGQFQAR 
TAEGVGVWPQ WQGQQPHHRS SSSEQHVQQT QAQAPSQPEV FQEMLSMLGD QSNTYNNEEF 
PDLTMFPPFS E

Genular Protein ID: 2936851506

Symbol: Q3ULM2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3ULM2

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 776
Mass: 85274
Checksum: 5C6608480699320C
Sequence:

MAATTANPEM TSDVPSLGPT IASGNPGPGI QGGGAVVQRA IKRRSGLDFD DEVEVNTKFL 
RCDDDQMCND KERFARENHS EIERRRRNKM TAYITELSDM VPTCSALARK PDKLTILRMA 
VSHMKSLRGT GNTSTDGSYK PSFLTDQELK HLILEAADGF LFIVSCETGR VVYVSDSVTP 
VLNQPQSEWF GSTLYDQVHP DDVDKLREQL STSENALTGR VLDLKTGTVK KEGQQSSMRM 
CMGSRRSFIC RMRCGTSSVD PVSMNRLSFL RNRCRNGLGS VKEGEPHFVV VHCTGYIKAW 
PPAGVSLPDD DPEAGQGSKF CLVAIGRLQV TSSPNCTDMS NICQPTEFIS RHNIEGIFTF 
VDHRCVATVG YQPQELLGKN IVEFCHPEDQ QLLRDSFQQV VKLKGQVLSV MFRFRSKTRE 
WLWMRTSSFT FQNPYSDEIE YIICTNTNVK NSSQEPRPTL SNTIPRSQLG PTANLSLEMG 
TGQLPSRQQQ QQHTELDMVP GRDGLASYNH SQVSVQPVAS AGSEHSKPLE KSEGLFAQDR 
DPRFPEIYPS ITADQSKGIS SSTVPATQQL FSQGSSFPPN PRPAENFRNS GLTPPVTIVQ 
PSSSAGQILA QISRHSNPAQ GSAPTWTSSS RPGFAAQQVP TQATAKTRSS QFGVNNFQTS 
SSFSAMSLPG APTASSGTAA YPALPNRGSN FPPETGQTTG QFQARTAEGV GVWPQWQGQQ 
PHHRSSSSEQ HVQQTQAQAP SQPEVFQEML SMLGDQSNTY NNEEFPDLTM FPPFSE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Arnt

Associated with

Other Information

Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT). PubMed ID: 8065341

Transcriptional activation function of the mouse Ah receptor nuclear translocator. PubMed ID: 7961746

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of a novel mechanism of regulation of Ah (dioxin) receptor function. PubMed ID: 9887096

Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development. PubMed ID: 11025203

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain. PubMed ID: 24001774

Structural integration in hypoxia-inducible factors. PubMed ID: 26245371

NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. PubMed ID: 27782878

Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation. PubMed ID: 28602820

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303