Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 88.9832
Cell Significance Index: -22.5700 - Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 43.7815
Cell Significance Index: -6.8100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 15.7994
Cell Significance Index: -19.4800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.6664
Cell Significance Index: -22.3600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 3.1380
Cell Significance Index: 89.5500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 3.0046
Cell Significance Index: 65.7900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.5970
Cell Significance Index: 114.8700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 2.4763
Cell Significance Index: 93.7700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.3293
Cell Significance Index: 467.2700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 2.1185
Cell Significance Index: 36.3100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.1035
Cell Significance Index: 754.5000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 2.0236
Cell Significance Index: 48.5300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.8048
Cell Significance Index: -3.9500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.7812
Cell Significance Index: 119.7700 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 1.7016
Cell Significance Index: 17.7300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.4586
Cell Significance Index: 89.6600 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.2257
Cell Significance Index: 16.3500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.2094
Cell Significance Index: 836.4500 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.0747
Cell Significance Index: 8.2400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.7877
Cell Significance Index: 44.2000 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.7780
Cell Significance Index: 10.0900 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.5437
Cell Significance Index: 6.7800 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: 0.1577
Cell Significance Index: 1.9900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1356
Cell Significance Index: 7.1200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0783
Cell Significance Index: 106.4900 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.0733
Cell Significance Index: 1.4500 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.0725
Cell Significance Index: 0.8000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0511
Cell Significance Index: 78.6900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.0462
Cell Significance Index: 1.4700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.0027
Cell Significance Index: 0.0900 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.0011
Cell Significance Index: 0.0100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0004
Cell Significance Index: 0.8400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0014
Cell Significance Index: -2.5100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0077
Cell Significance Index: -4.9100 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0165
Cell Significance Index: -0.3500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0267
Cell Significance Index: -19.5900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0316
Cell Significance Index: -23.8900 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0321
Cell Significance Index: -0.3500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0321
Cell Significance Index: -23.8100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0344
Cell Significance Index: -18.7600 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0379
Cell Significance Index: -0.7600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0408
Cell Significance Index: -2.6300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0409
Cell Significance Index: -18.5500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0453
Cell Significance Index: -25.5600 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0733
Cell Significance Index: -1.0500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0745
Cell Significance Index: -14.7800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0776
Cell Significance Index: -22.3300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0843
Cell Significance Index: -15.1900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0929
Cell Significance Index: -1.3300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0962
Cell Significance Index: -16.4200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0991
Cell Significance Index: -14.4000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1034
Cell Significance Index: -2.8900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1104
Cell Significance Index: -6.9600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1265
Cell Significance Index: -15.5500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1265
Cell Significance Index: -26.6500 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.1333
Cell Significance Index: -1.1000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1571
Cell Significance Index: -21.5800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1649
Cell Significance Index: -21.3100 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.1680
Cell Significance Index: -2.1200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1741
Cell Significance Index: -20.5400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1850
Cell Significance Index: -18.9000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.2093
Cell Significance Index: -5.2200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2097
Cell Significance Index: -4.5300 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2137
Cell Significance Index: -3.9500 - Cell Name: neural cell (CL0002319)
Fold Change: -0.2177
Cell Significance Index: -2.5400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2253
Cell Significance Index: -28.8900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2280
Cell Significance Index: -17.5000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2312
Cell Significance Index: -26.4900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2385
Cell Significance Index: -24.8300 - Cell Name: neuron (CL0000540)
Fold Change: -0.2490
Cell Significance Index: -2.3600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2900
Cell Significance Index: -21.6100 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.2937
Cell Significance Index: -6.1300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2994
Cell Significance Index: -10.4900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3090
Cell Significance Index: -16.1000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3286
Cell Significance Index: -17.0700 - Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
Fold Change: -0.3292
Cell Significance Index: -3.3900 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -0.3622
Cell Significance Index: -4.3900 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.3913
Cell Significance Index: -4.6800 - Cell Name: chandelier cell (CL4023083)
Fold Change: -0.4062
Cell Significance Index: -3.2800 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: -0.4166
Cell Significance Index: -2.7100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4345
Cell Significance Index: -20.4200 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.4434
Cell Significance Index: -5.5000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4516
Cell Significance Index: -15.6900 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: -0.4797
Cell Significance Index: -5.4300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.4973
Cell Significance Index: -22.5400 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.5071
Cell Significance Index: -9.9800 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.5657
Cell Significance Index: -11.2800 - Cell Name: radial glial cell (CL0000681)
Fold Change: -0.5789
Cell Significance Index: -3.4400 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.6020
Cell Significance Index: -4.6400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.6042
Cell Significance Index: -22.1800 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.6281
Cell Significance Index: -13.4300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.6295
Cell Significance Index: -29.3500 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.6295
Cell Significance Index: -19.9100 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.6317
Cell Significance Index: -4.2800 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.6447
Cell Significance Index: -18.9900 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.6620
Cell Significance Index: -8.8300 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.6857
Cell Significance Index: -7.7900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.7380
Cell Significance Index: -19.4100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.7429
Cell Significance Index: -21.3000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.7613
Cell Significance Index: -26.7500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2158869954
Symbol: ADDB_HUMAN
Name: Beta-adducin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1840603
Title: Primary structure and domain organization of human alpha and beta adducin.
PubMed ID: 1840603
PubMed ID: 12951058
Title: Expression analysis of the human adducin gene family and evidence of ADD2 beta4 multiple splicing variants.
PubMed ID: 12951058
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 21697133
Title: Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.
PubMed ID: 21697133
DOI: 10.1167/iovs.11-7479
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8566798
Title: Genomic organisation and chromosomal localisation of the gene encoding human beta adducin.
PubMed ID: 8566798
PubMed ID: 8810272
Title: Adducin regulation. Definition of the calmodulin-binding domain and sites of phosphorylation by protein kinases A and C.
PubMed ID: 8810272
PubMed ID: 18347014
Title: Dematin and adducin provide a novel link between the spectrin cytoskeleton and human erythrocyte membrane by directly interacting with glucose transporter-1.
PubMed ID: 18347014
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 726
- Mass: 80854
- Checksum: B07F7303D929DBA4
- Sequence:
MSEETVPEAA SPPPPQGQPY FDRFSEDDPE YMRLRNRAAD LRQDFNLMEQ KKRVTMILQS PSFREELEGL IQEQMKKGNN SSNIWALRQI ADFMASTSHA VFPTSSMNVS MMTPINDLHT ADSLNLAKGE RLMRCKISSV YRLLDLYGWA QLSDTYVTLR VSKEQDHFLI SPKGVSCSEV TASSLIKVNI LGEVVEKGSS CFPVDTTGFC LHSAIYAARP DVRCIIHLHT PATAAVSAMK WGLLPVSHNA LLVGDMAYYD FNGEMEQEAD RINLQKCLGP TCKILVLRNH GVVALGDTVE EAFYKIFHLQ AACEIQVSAL SSAGGVENLI LLEQEKHRPH EVGSVQWAGS TFGPMQKSRL GEHEFEALMR MLDNLGYRTG YTYRHPFVQE KTKHKSEVEI PATVTAFVFE EDGAPVPALR QHAQKQQKEK TRWLNTPNTY LRVNVADEVQ RSMGSPRPKT TWMKADEVEK SSSGMPIRIE NPNQFVPLYT DPQEVLEMRN KIREQNRQDV KSAGPQSQLL ASVIAEKSRS PSTESQLMSK GDEDTKDDSE ETVPNPFSQL TDQELEEYKK EVERKKLELD GEKETAPEEP GSPAKSAPAS PVQSPAKEAE TKSPLVSPSK SLEEGTKKTE TSKAATTEPE TTQPEGVVVN GREEEQTAEE ILSKGLSQMT TSADTDVDTS KDKTESVTSG PMSPEGSPSK SPSKKKKKFR TPSFLKKSKK KEKVES
Genular Protein ID: 896790978
Symbol: Q05DK5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 709
- Mass: 78833
- Checksum: 98E0752152DC77B6
- Sequence:
MSEETVPEAA SPPPPQGQPY FDRFSEDDPE YMRLRNRAAD LRQDFNLMEQ KKRVTMILQS PSFREELEGL IQEQMKKGNN SSNIWALRQI ADFMASTSHA VFPTSSMNVS MMTPINDLHT ADSLNLAKGE RLMRCKISSV YRLLDLYGWA QLSDTYVTLR VSKEQDHFLI SPKGVSCSEV TASSLIKVNI LGEVVEKGSS CFPVDTTGFC LHSAIYAARP DVRCIIHLHT PATAAVSAMK WGLLPVSHNA LLVGDMAYYD FNGEMEQEAD RINLQKCLGP TCKILVLRNH GVVALGDTVE EAFYKIFHLQ AACEIQVSAL SSAGGVENLI LLEQEKHRPH EVGSVQWAGS TFGPMQKSRL GEHEFEALMR MLDNLGYRTG YTYRHPFVQE KTKHKSEVEI PATVTAFVFE EDGAPVPALR QHAQKQQKEK TRWLNTPNTY LRVNVADEVQ RSMGSPRPKT TWMKADEVEK SSSGMPIRIE NPNQFVPLYT DPQEVLEMRN KIREQNRQDV KSAGPQSQLL ASVIAEKSRS PSTESQLMSK GDEDTKDDSE ETVPNPFSQL TDQELEEYKK EVERKKLELD GEKETAPEEP GSPAKSAPAS PVQSPAKEAE TKSPLVSPSK SLEEGTKKTE TSKAATTEPE TTQPEGVVVN GREEEQTAEE ILSKGLSQMT TSADTDVDTS KDKTESVTSG PMSPEGSPSK SPSKKKKKK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.