Details for: Atf3

Gene ID: 11910

Symbol: Atf3

Ensembl ID: ENSMUSG00000026628

Description: activating transcription factor 3

Associated with

  • Cellular response to amino acid starvation
    (GO:0034198)
  • Chop-atf3 complex
    (GO:1990622)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Endoplasmic reticulum unfolded protein response
    (GO:0030968)
  • Gluconeogenesis
    (GO:0006094)
  • Identical protein binding
    (GO:0042802)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of erk1 and erk2 cascade
    (GO:0070373)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleolus
    (GO:0005730)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of trail-activated apoptotic signaling pathway
    (GO:1903984)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein heterodimerization activity
    (GO:0046982)
  • Protein homodimerization activity
    (GO:0042803)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to endoplasmic reticulum stress
    (GO:0034976)
  • Response to organic substance
    (GO:0010033)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulator complex
    (GO:0090575)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Skeletal muscle cell differentiation
    (GO:0035914)
  • Transcription cis-regulatory region binding
    (GO:0000976)

Other Information

Genular Protein ID: 1794858237

Symbol: ATF3_MOUSE

Name: Cyclic AMP-dependent transcription factor ATF-3

UniProtKB Accession Codes:

Q60765

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 31 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8960123

Title: Identification of a lipopolysaccharide inducible transcription factor in murine macrophages.

PubMed ID: 8960123

DOI: 10.1016/s0161-5890(96)00043-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11916968

Title: The roles of ATF3 in liver dysfunction and the regulation of phosphoenolpyruvate carboxykinase gene expression.

PubMed ID: 11916968

DOI: 10.1074/jbc.m200727200

PubMed ID: 22242125

Title: Stress-induced C/EBP homology protein (CHOP) represses MyoD transcription to delay myoblast differentiation.

PubMed ID: 22242125

DOI: 10.1371/journal.pone.0029498

Sequence Information:

  • Length: 181
  • Mass: 20722
  • Checksum: D641C8C6D14A457D
  • Sequence:
    • MMLQHPGQVS ASEVSATAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS 
ALESVTVNNR PLEMSVTKSE AAPEEDERKR RRRERNKIAA AKCRNKKKEK TECLQKESEK 
LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ 
S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.