Genular: Defining Cellular Identity and Function

Details for: Atoh1

Gene ID: 11921

Symbol: Atoh1

Ensembl ID: ENSMUSG00000073043

Description: atonal bHLH transcription factor 1

Associated with

Auditory receptor cell fate determination
(GO:0042668)
Auditory receptor cell fate specification
(GO:0042667)
Axon development
(GO:0061564)
Axon guidance
(GO:0007411)
Brain development
(GO:0007420)
Cell differentiation
(GO:0030154)
Cerebral cortex development
(GO:0021987)
Chromatin dna binding
(GO:0031490)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna binding
(GO:0003677)
E-box binding
(GO:0070888)
Epithelial cell apoptotic process
(GO:1904019)
Inner ear auditory receptor cell differentiation
(GO:0042491)
Inner ear development
(GO:0048839)
Inner ear morphogenesis
(GO:0042472)
Multicellular organism development
(GO:0007275)
Negative regulation of epithelial cell apoptotic process
(GO:1904036)
Negative regulation of gliogenesis
(GO:0014014)
Nervous system development
(GO:0007399)
Neuroblast migration
(GO:0097402)
Neuron differentiation
(GO:0030182)
Neuron fate commitment
(GO:0048663)
Neuron migration
(GO:0001764)
Notch signaling pathway
(GO:0007219)
Nucleus
(GO:0005634)
Positive regulation of inner ear auditory receptor cell differentiation
(GO:0045609)
Positive regulation of inner ear receptor cell differentiation
(GO:2000982)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Regulation of neuron differentiation
(GO:0045664)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sensory organ development
(GO:0007423)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription by rna polymerase ii
(GO:0006366)

Other Information

Proteins

ATOH1_MOUSE

Genular Protein ID: 1860620455

Symbol: ATOH1_MOUSE

Name: N/A

UniProtKB Accession Codes:

P48985

Database IDs:

Citations:

PubMed ID: 7721778

Title: A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system.

PubMed ID: 7721778

DOI: 10.1074/jbc.270.15.8730

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10648228

Title: Generation of neurons by transient expression of neural bHLH proteins in mammalian cells.

PubMed ID: 10648228

DOI: 10.1242/dev.127.4.693

PubMed ID: 17977745

Title: Math5 expression and function in the central auditory system.

PubMed ID: 17977745

DOI: 10.1016/j.mcn.2007.09.006

Sequence Information:

Length: 351
Mass: 37854
Checksum: 596E03DF23C3BF96
Sequence:

MSRLLHAEEW AEVKELGDHH RHPQPHHVPP LTPQPPATLQ ARDLPVYPAE LSLLDSTDPR 
AWLTPTLQGL CTARAAQYLL HSPELGASEA AAPRDEADSQ GELVRRSGCG GLSKSPGPVK 
VREQLCKLKG GVVVDELGCS RQRAPSSKQV NGVQKQRRLA ANARERRRMH GLNHAFDQLR 
NVIPSFNNDK KLSKYETLQM AQIYINALSE LLQTPNVGEQ PPPPTASCKN DHHHLRTASS 
YEGGAGASAV AGAQPAPGGG PRPTPPGPCR TRFSGPASSG GYSVQLDALH FPAFEDRALT 
AMMAQKDLSP SLPGGILQPV QEDNSKTSPR SHRSDGEFSP HSHYSDSDEA S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Atoh1

Associated with

Other Information

A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system. PubMed ID: 7721778

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. PubMed ID: 10648228

Math5 expression and function in the central auditory system. PubMed ID: 17977745

Database document:

PubMed ID: 7721778

PubMed ID: 15489334

PubMed ID: 10648228

PubMed ID: 17977745