Genular: Defining Cellular Identity and Function

Details for: Atp1a1

Gene ID: 11928

Symbol: Atp1a1

Ensembl ID: ENSMUSG00000033161

Description: ATPase, Na+/K+ transporting, alpha 1 polypeptide

Associated with

Cardiac conduction
(R-MMU-5576891)
Ion channel transport
(R-MMU-983712)
Ion homeostasis
(R-MMU-5578775)
Ion transport by p-type atpases
(R-MMU-936837)
Muscle contraction
(R-MMU-397014)
Transport of small molecules
(R-MMU-382551)
Adp binding
(GO:0043531)
Ankyrin binding
(GO:0030506)
Apical plasma membrane
(GO:0016324)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Basolateral plasma membrane
(GO:0016323)
Caveola
(GO:0005901)
Cell projection
(GO:0042995)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to steroid hormone stimulus
(GO:0071383)
Endoplasmic reticulum
(GO:0005783)
Endosome
(GO:0005768)
Establishment or maintenance of transmembrane electrochemical gradient
(GO:0010248)
Golgi apparatus
(GO:0005794)
Heart contraction
(GO:0060047)
Intercalated disc
(GO:0014704)
Intracellular potassium ion homeostasis
(GO:0030007)
Intracellular sodium ion homeostasis
(GO:0006883)
Lateral plasma membrane
(GO:0016328)
Membrane
(GO:0016020)
Membrane hyperpolarization
(GO:0060081)
Membrane repolarization
(GO:0086009)
Metal ion binding
(GO:0046872)
Monoatomic ion transport
(GO:0006811)
Myelin sheath
(GO:0043209)
Negative regulation of glucocorticoid biosynthetic process
(GO:0031947)
Negative regulation of heart contraction
(GO:0045822)
Nucleotide binding
(GO:0000166)
Organelle membrane
(GO:0031090)
Osmosensory signaling pathway
(GO:0007231)
P-type potassium transmembrane transporter activity
(GO:0008556)
P-type sodium:potassium-exchanging transporter activity
(GO:0005391)
Phosphatase activity
(GO:0016791)
Phosphatidylinositol 3-kinase binding
(GO:0043548)
Plasma membrane
(GO:0005886)
Positive regulation of heart contraction
(GO:0045823)
Positive regulation of striated muscle contraction
(GO:0045989)
Postsynaptic density
(GO:0014069)
Potassium ion binding
(GO:0030955)
Potassium ion import across plasma membrane
(GO:1990573)
Potassium ion transport
(GO:0006813)
Protein-containing complex
(GO:0032991)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein heterodimerization activity
(GO:0046982)
Protein kinase binding
(GO:0019901)
Proton transmembrane transport
(GO:1902600)
Regulation of blood pressure
(GO:0008217)
Regulation of cardiac muscle cell contraction
(GO:0086004)
Regulation of sodium ion transport
(GO:0002028)
Regulation of the force of heart contraction
(GO:0002026)
Response to glycoside
(GO:1903416)
Response to xenobiotic stimulus
(GO:0009410)
Sarcolemma
(GO:0042383)
Sodium:potassium-exchanging atpase complex
(GO:0005890)
Sodium ion binding
(GO:0031402)
Sodium ion export across plasma membrane
(GO:0036376)
Sodium ion homeostasis
(GO:0055078)
Sodium ion transport
(GO:0006814)
Sperm flagellum
(GO:0036126)
Steroid hormone binding
(GO:1990239)
T-tubule
(GO:0030315)
Transmembrane transport
(GO:0055085)
Transporter activity
(GO:0005215)

Other Information

Proteins

Sodium/potassium-transporting ATPase subunit alpha-1

Genular Protein ID: 714345026

Symbol: AT1A1_MOUSE

Name: Sodium/potassium-transporting ATPase subunit alpha-1

UniProtKB Accession Codes:

Q8VDN2 Q91Z09

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17283221

Title: The intracellular region of FXYD1 is sufficient to regulate cardiac Na/K ATPase.

PubMed ID: 17283221

DOI: 10.1096/fj.06-7269com

PubMed ID: 15743908

Title: FXYD3 (Mat-8), a new regulator of Na,K-ATPase.

PubMed ID: 15743908

DOI: 10.1091/mbc.e04-10-0878

PubMed ID: 17114649

Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PubMed ID: 17114649

DOI: 10.1074/mcp.m600046-mcp200

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 1023
Mass: 112982
Checksum: 1E806D3FDFC5AD80
Sequence:

MGKGVGRDKY EPAAVSEHGD KKGKKAKKER DMDELKKEVS MDDHKLSLDE LHRKYGTDLS 
RGLTPARAAE ILARDGPNAL TPPPTTPEWV KFCRQLFGGF SMLLWIGAIL CFLAYGIRSA 
TEEEPPNDDL YLGVVLSAVV IITGCFSYYQ EAKSSKIMES FKNMVPQQAL VIRNGEKMSI 
NAEDVVVGDL VEVKGGDRIP ADLRIISANG CKVDNSSLTG ESEPQTRSPD FTNENPLETR 
NIAFFSTNCV EGTARGIVVY TGDRTVMGRI ATLASGLEGG QTPIAEEIEH FIHLITGVAV 
FLGVSFFILS LILEYTWLEA VIFLIGIIVA NVPEGLLATV TVCLTLTAKR MARKNCLVKN 
LEAVETLGST STICSDKTGT LTQNRMTVAH MWFDNQIHEA DTTENQSGVS FDKTSATWFA 
LSRIAGLCNR AVFQANQENL PILKRAVAGD ASESALLKCI EVCCGSVMEM REKYSKIVEI 
PFNSTNKYQL SIHKNPNASE PKHLLVMKGA PERILDRCSS ILLHGKEQPL DEELKDAFQN 
AYLELGGLGE RVLGFCHLLL PDEQFPEGFQ FDTDDVNFPV DNLCFVGLIS MIDPPRAAVP 
DAVGKCRSAG IKVIMVTGDH PITAKAIAKG VGIISEGNET VEDIAARLNI PVNQVNPRDA 
KACVVHGSDL KDMTSEELDD ILRYHTEIVF ARTSPQQKLI IVEGCQRQGA IVAVTGDGVN 
DSPALKKADI GVAMGIVGSD VSKQAADMIL LDDNFASIVT GVEEGRLIFD NLKKSIAYTL 
TSNIPEITPF LIFIIANIPL PLGTVTILCI DLGTDMVPAI SLAYEQAESD IMKRQPRNPK 
TDKLVNERLI SMAYGQIGMI QALGGFFTYF VILAENGFLP FHLLGIRETW DDRWVNDVED 
SYGQQWTYEQ RKIVEFTCHT AFFVSIVVVQ WADLVICKTR RNSVFQQGMK NKILIFGLFE 
ETALAAFLSY CPGMGAALRM YPLKPTWWFC AFPYSLLIFV YDEVRKLIIR RRPGGWVEKE 
TYY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Atp1a1

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The intracellular region of FXYD1 is sufficient to regulate cardiac Na/K ATPase. PubMed ID: 17283221

FXYD3 (Mat-8), a new regulator of Na,K-ATPase. PubMed ID: 15743908

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. PubMed ID: 17114649

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337