Genular: Defining Cellular Identity and Function

Details for: Atp5f1a

Gene ID: 11946

Symbol: Atp5f1a

Ensembl ID: ENSMUSG00000025428

Description: ATP synthase F1 subunit alpha

Associated with

Cristae formation
(R-MMU-8949613)
Formation of atp by chemiosmotic coupling
(R-MMU-163210)
Metabolism
(R-MMU-1430728)
Metabolism of proteins
(R-MMU-392499)
Mitochondrial biogenesis
(R-MMU-1592230)
Mitochondrial protein degradation
(R-MMU-9837999)
Organelle biogenesis and maintenance
(R-MMU-1852241)
Respiratory electron transport, atp synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
(R-MMU-163200)
The citric acid (tca) cycle and respiratory electron transport
(R-MMU-1428517)
Adenyl ribonucleotide binding
(GO:0032559)
Adp binding
(GO:0043531)
Angiostatin binding
(GO:0043532)
Atp binding
(GO:0005524)
Atp biosynthetic process
(GO:0006754)
Atp hydrolysis activity
(GO:0016887)
Atp metabolic process
(GO:0046034)
Cell surface
(GO:0009986)
Cop9 signalosome
(GO:0008180)
Embryo development
(GO:0009790)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Mhc class i protein binding
(GO:0042288)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial proton-transporting atp synthase, catalytic core
(GO:0005754)
Mitochondrial proton-transporting atp synthase complex
(GO:0005753)
Mitochondrial proton-transporting atp synthase complex, catalytic sector f(1)
(GO:0000275)
Mitochondrion
(GO:0005739)
Monoatomic ion transport
(GO:0006811)
Myelin sheath
(GO:0043209)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Nucleotide binding
(GO:0000166)
Plasma membrane
(GO:0005886)
Positive regulation of blood vessel endothelial cell migration
(GO:0043536)
Protease binding
(GO:0002020)
Protein binding
(GO:0005515)
Proton-transporting atp synthase activity, rotational mechanism
(GO:0046933)
Proton-transporting atp synthase complex
(GO:0045259)
Proton-transporting atp synthase complex, catalytic core f(1)
(GO:0045261)
Proton motive force-driven atp synthesis
(GO:0015986)
Proton motive force-driven mitochondrial atp synthesis
(GO:0042776)
Proton transmembrane transport
(GO:1902600)

Other Information

Proteins

ATPA_MOUSE

Genular Protein ID: 1122641477

Symbol: ATPA_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q03265 Q3TFN0 Q3THN8 Q3TPR0 Q3TPV3 Q3TZU3 Q3UIR7 Q543Y6

Database IDs:

Citations:

PubMed ID: 7916601

Title: Cloning and functional expression analysis of the alpha subunit of mouse ATP synthase.

PubMed ID: 7916601

DOI: 10.1006/bbrc.1993.1195

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15648052

Title: Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.

PubMed ID: 15648052

DOI: 10.1002/pmic.200401066

PubMed ID: 17438143

Title: Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes.

PubMed ID: 17438143

DOI: 10.1128/mcb.02045-06

PubMed ID: 19941651

Title: Novel interactions of CLN5 support molecular networking between neuronal ceroid lipofuscinosis proteins.

PubMed ID: 19941651

DOI: 10.1186/1471-2121-10-83

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 553
Mass: 59753
Checksum: CF35B4FBA7ED431D
Sequence:

MLSVRVAAAV ARALPRRAGL VSKNALGSSF VGARNLHASN TRLQKTGTAE MSSILEERIL 
GADTSVDLEE TGRVLSIGDG IARVHGLRNV QAEEMVEFSS GLKGMSLNLE PDNVGVVVFG 
NDKLIKEGDV VKRTGAIVDV PVGEELLGRV VDALGNAIDG KGPIGSKTRR RVGLKAPGII 
PRISVREPMQ TGIKAVDSLV PIGRGQRELI IGDRQTGKTS IAIDTIINQK RFNDGTDEKK 
KLYCIYVAIG QKRSTVAQLV KRLTDADAMK YTIVVSATAS DAAPLQYLAP YSGCSMGEYF 
RDNGKHALII YDDLSKQAVA YRQMSLLLRR PPGREAYPGD VFYLHSRLLE RAAKMNDSFG 
GGSLTALPVI ETQAGDVSAY IPTNVISITD GQIFLETELF YKGIRPAINV GLSVSRVGSA 
AQTRAMKQVA GTMKLELAQY REVAAFAQFG SDLDAATQQL LSRGVRLTEL LKQGQYSPMA 
IEEQVAVIYA GVRGYLDKLE PSKITKFENA FLSHVISQHQ SLLGNIRSDG KISEQSDAKL 
KEIVTNFLAG FEP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Atp5f1a

Associated with

Other Information

Cloning and functional expression analysis of the alpha subunit of mouse ATP synthase. PubMed ID: 7916601

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol. PubMed ID: 15648052

Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes. PubMed ID: 17438143

Novel interactions of CLN5 support molecular networking between neuronal ceroid lipofuscinosis proteins. PubMed ID: 19941651

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315