Genular: Defining Cellular Identity and Function

Details for: Atp6v1e1

Gene ID: 11973

Symbol: Atp6v1e1

Ensembl ID: ENSMUSG00000019210

Description: ATPase, H+ transporting, lysosomal V1 subunit E1

Associated with

Amino acids regulate mtorc1
(R-MMU-9639288)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to starvation
(R-MMU-9711097)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Insulin receptor recycling
(R-MMU-77387)
Ion channel transport
(R-MMU-983712)
Iron uptake and transport
(R-MMU-917937)
Ros and rns production in phagocytes
(R-MMU-1222556)
Signaling by insulin receptor
(R-MMU-74752)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Transferrin endocytosis and recycling
(R-MMU-917977)
Transport of small molecules
(R-MMU-382551)
Apical plasma membrane
(GO:0016324)
Atpase binding
(GO:0051117)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Endosome
(GO:0005768)
Extrinsic component of synaptic vesicle membrane
(GO:0098850)
Membrane
(GO:0016020)
Microvillus
(GO:0005902)
Mitochondrion
(GO:0005739)
Monoatomic ion transport
(GO:0006811)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Proton-transporting atpase activity, rotational mechanism
(GO:0046961)
Proton-transporting two-sector atpase complex, catalytic domain
(GO:0033178)
Proton transmembrane transport
(GO:1902600)
Synapse
(GO:0045202)
Synaptic vesicle lumen acidification
(GO:0097401)
Vacuolar proton-transporting v-type atpase, v1 domain
(GO:0000221)

Other Information

Proteins

V-type proton ATPase subunit E 1

Genular Protein ID: 2179787002

Symbol: VATE1_MOUSE

Name: V-type proton ATPase subunit E 1

UniProtKB Accession Codes:

P50518 Q3UK59 Q8K5D6 Q99LD0

Database IDs:

Citations:

PubMed ID: 8741845

Title: Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts.

PubMed ID: 8741845

DOI: 10.1091/mbc.7.1.129

PubMed ID: 11872743

Title: A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification.

PubMed ID: 11872743

DOI: 10.1074/jbc.m111567200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23055941

Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

PubMed ID: 23055941

DOI: 10.1371/journal.pgen.1002969

PubMed ID: 29993276

Title: H+-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney.

PubMed ID: 29993276

DOI: 10.1152/ajprenal.00539.2017

Sequence Information:

Length: 226
Mass: 26157
Checksum: 5DD7B0EAB181EA08
Sequence:

MALSDADVQK QIKHMMAFIE QEANEKAEEI DAKAEEEFNI EKGRLVQTQR LKIMEYYEKK 
EKQIEQQKKI QMSNLMNQAR LKVLRARDDL ITDLLNEAKQ RLSKVVKDTT RYQVLLDGLV 
LQGLYQLLEP RMIVRCRKQD FPLVKAAVQK AIPMYKIATK KDVDVQIDQE AYLPEEIAGG 
VEIYNGDRKI KVSNTLESRL DLIAQQMMPE VRGALFGANA NRKFLD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Atp6v1e1

Associated with

Other Information

Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts. PubMed ID: 8741845

A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification. PubMed ID: 11872743

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PubMed ID: 23055941

H+-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney. PubMed ID: 29993276