Genular: Defining Cellular Identity and Function

Details for: Atp7b

Gene ID: 11979

Symbol: Atp7b

Ensembl ID: ENSMUSG00000006567

Description: ATPase, Cu++ transporting, beta polypeptide

Associated with

Ion channel transport
(R-MMU-983712)
Ion transport by p-type atpases
(R-MMU-936837)
Transport of small molecules
(R-MMU-382551)
Apical part of cell
(GO:0045177)
Atpase-coupled monoatomic cation transmembrane transporter activity
(GO:0019829)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Basolateral plasma membrane
(GO:0016323)
Bicellular tight junction
(GO:0005923)
Cellular response to copper ion
(GO:0071280)
Copper ion binding
(GO:0005507)
Copper ion export
(GO:0060003)
Copper ion import
(GO:0015677)
Copper ion transmembrane transporter activity
(GO:0005375)
Copper ion transport
(GO:0006825)
Cytoplasmic vesicle
(GO:0031410)
Endosome
(GO:0005768)
Establishment of localization in cell
(GO:0051649)
Golgi apparatus
(GO:0005794)
Intracellular copper ion homeostasis
(GO:0006878)
Intracellular zinc ion homeostasis
(GO:0006882)
Lactation
(GO:0007595)
Late endosome
(GO:0005770)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monoatomic cation transport
(GO:0006812)
Monoatomic ion transport
(GO:0006811)
Nucleotide binding
(GO:0000166)
P-type divalent copper transporter activity
(GO:0043682)
P-type monovalent copper transporter activity
(GO:0140581)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Protein maturation by copper ion transfer
(GO:0015680)
Response to copper ion
(GO:0046688)
Sequestering of calcium ion
(GO:0051208)
Tight junction
(GO:0070160)
Trans-golgi network
(GO:0005802)
Trans-golgi network membrane
(GO:0032588)
Transporter activity
(GO:0005215)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Copper-transporting ATPase 2

Genular Protein ID: 1556387555

Symbol: ATP7B_MOUSE

Name: Copper-transporting ATPase 2

UniProtKB Accession Codes:

Q64446 B1AQ56

Database IDs:

Citations:

PubMed ID: 8894697

Title: The toxic milk mouse is a murine model of Wilson disease.

PubMed ID: 8894697

DOI: 10.1093/hmg/5.10.1619

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1462
Mass: 157190
Checksum: BEC219F80EB74214
Sequence:

MDPRKNLASV GTMPEQERQV TAKEASRKIL SKLALPGRPW EQSMKQSFAF DNVGYEGGLD 
STSSSPAATD VVNILGMTCH SCVKSIEDRI SSLKGIVNIK VSLEQGSATV RYVPSVMNLQ 
QICLQIEDMG FEASAAEGKA ASWPSRSSPA QEAVVKLRVE GMTCQSCVSS IEGKIRKLQG 
VVRIKVSLSN QEAVITYQPY LIQPEDLRDH ICDMGFEAAI KNRTAPLRLG PIDVNKLEST 
NLKKETVSPV QISNHFETLG HQGSYLATLP LRIDGMHCKS CVLNIEGNIG QLPGVQNIHV 
SLENKTAQIQ YDPSCVTPMF LQTAIEALPP GHFKVSLPDG VEENEPQSGS SQRHQEQGPG 
RTAVLTISGI TCASSVQPIE DMLSQRKGVQ QTSISLAEGT GAVLYDPSIV SLDELRTAVE 
DMGFEVSVNS ETFTINPVRN FKSGNSVPQT MGDIAGSVQK MAPDTRGLPT HQGPGHSSET 
PSSPGATASQ KCFVQIKGMT CASCVSNIER SLQRHAGILS VLVALMSGKA EVKYDPEIIQ 
SPRIAQLIQD LGFEASVMED NTVSEGDIEL IITGMTCASC VHNIESKLTR TNGITYASVA 
LATSKAHVKF DPEIVGPRDI IKIIEEIGFH ASLAQRNPNA HHLDHKTEIK QWKKSFLCSL 
VFGIPVMGLM VYMLIPSSTP QETMVLDHNI IPGLSVLNLI FFILCTFVQF LGGWYFYVQA 
YKSLRHRSAN MDVLIVLATT IAYAYSLVIL VVAVAEKAEK SPVTFFDTPP MLFVFIALGR 
WLEHVAKSKT SEALAKLMSL QATEATVVTL GEDNLILREE QVPMELVQRG DVIKVVPGGK 
FPVDGKVLEG NTMADESLIT GEAMPVTKKP GSIVIAGSIN AHGSVLLKAT HVGNDTTLAQ 
IVKLVEEAQM SKAPIQQLAD RFSGYFVPFI IIISTLTLVV WIVIGFVDFG VVQKYFPSPS 
KHISQTEVII RFAFQTSITV LCIACPCSLG LATPTAVMVG TGVAAQNGVL IKGGKPLEMA 
HKIKTVMFDK TGTITHGVPR VMRFLLLADV ATLPLRKVLA VVGTAEASSE HPLGVAVTKY 
CKEELGTETL GYSTDFQAVP GCGISCKVSN VEGILARSDL TAHPVGVGNP PTGEGAGPQT 
FSVLIGNREW MRRNGLTISS DISDAMTDHE MKGQTAILVA IDGVLCGMIA IADAVKPEAA 
LAIYTLKSMG VDVALITGDN RKTARAIATQ VGINKVFAEV LPSHKVAKVQ ELQNEGKKVA 
MVGDGVNDSP ALAQADVGIA IGTGTDVAIE AADVVLIRND LLDVVASIHL SKRTVRRIRV 
NLVLALIYNM VGIPIAAGVF MPIGIVLQPW MGSAAMAASS VSVVLSSLQL KCYRKPDLER 
YEAQAHGRMK PLSASQVSVH IGMDDRRRDS PRATAWDQVS YVSQVSLSSL TSDRLSRHGG 
AAEDGGDKWS LLLSDRDEEQ CI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.