Slc7a1 | ENSMUSG00000041313 | NCBI 11987

Details for: Slc7a1

Gene ID: 11987

Symbol: Slc7a1

Ensembl ID: ENSMUSG00000041313

Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 1

Associated with

Amino acid transport across the plasma membrane
(R-MMU-352230)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-MMU-425393)
Transport of small molecules
(R-MMU-382551)
Amino acid import across plasma membrane
(GO:0089718)
Amino acid transmembrane transporter activity
(GO:0015171)
Amino acid transport
(GO:0006865)
Apical plasma membrane
(GO:0016324)
Basal plasma membrane
(GO:0009925)
Basic amino acid transmembrane transporter activity
(GO:0015174)
Basolateral plasma membrane
(GO:0016323)
L-amino acid transport
(GO:0015807)
L-arginine import across plasma membrane
(GO:0097638)
L-arginine transmembrane transport
(GO:1903826)
L-arginine transmembrane transporter activity
(GO:0061459)
L-histidine import across plasma membrane
(GO:1903810)
L-histidine transmembrane transporter activity
(GO:0005290)
L-lysine transmembrane transporter activity
(GO:0015189)
L-ornithine transmembrane transport
(GO:1903352)
L-ornithine transmembrane transporter activity
(GO:0000064)
Lysine transport
(GO:0015819)
Membrane
(GO:0016020)
Ornithine transport
(GO:0015822)
Plasma membrane
(GO:0005886)
Positive regulation of t cell proliferation
(GO:0042102)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Regulation of tor signaling
(GO:0032006)
Transmembrane transport
(GO:0055085)
Transmembrane transporter activity
(GO:0022857)
Virus receptor activity
(GO:0001618)

Other Information

Proteins

High affinity cationic amino acid transporter 1
Q3TQZ8_MOUSE

Genular Protein ID: 1040269577

Symbol: CTR1_MOUSE

Name: High affinity cationic amino acid transporter 1

UniProtKB Accession Codes:

Q09143 P30824

Database IDs:

Citations:

PubMed ID: 2541919

Title: A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection.

PubMed ID: 2541919

DOI: 10.1016/0092-8674(89)90134-7

PubMed ID: 1652100

Title: Transport of cationic amino acids by the mouse ecotropic retrovirus receptor.

PubMed ID: 1652100

DOI: 10.1038/352725a0

PubMed ID: 1908564

Title: Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter.

PubMed ID: 1908564

DOI: 10.1038/352729a0

PubMed ID: 9174363

Title: Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties.

PubMed ID: 9174363

DOI: 10.1021/bi962829p

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22081021

Title: Requirement of argininosuccinate lyase for systemic nitric oxide production.

PubMed ID: 22081021

DOI: 10.1038/nm.2544

PubMed ID: 25683716

Title: The mitochondrial metallochaperone SCO1 is required to sustain expression of the high-affinity copper transporter CTR1 and preserve copper homeostasis.

PubMed ID: 25683716

DOI: 10.1016/j.celrep.2015.01.019

PubMed ID: 28973536

Title: The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart.

PubMed ID: 28973536

DOI: 10.1093/hmg/ddx344

Sequence Information:

Length: 622
Mass: 67092
Checksum: 157EE960CE737B6E
Sequence:

MGCKNLLGLG QQMLRRKVVD CSREESRLSR CLNTYDLVAL GVGSTLGAGV YVLAGAVARE 
NAGPAIVISF LIAALASVLA GLCYGEFGAR VPKTGSAYLY SYVTVGELWA FITGWNLILS 
YIIGTSSVAR AWSATFDELI GKPIGEFSRQ HMALNAPGVL AQTPDIFAVI IIIILTGLLT 
LGVKESAMVN KIFTCINVLV LCFIVVSGFV KGSIKNWQLT EKNFSCNNND TNVKYGEGGF 
MPFGFSGVLS GAATCFYAFV GFDCIATTGE EVKNPQKAIP VGIVASLLIC FIAYFGVSAA 
LTLMMPYFCL DIDSPLPGAF KHQGWEEAKY AVAIGSLCAL STSLLGSMFP MPRVIYAMAE 
DGLLFKFLAK INNRTKTPVI ATVTSGAIAA VMAFLFELKD LVDLMSIGTL LAYSLVAACV 
LVLRYQPEQP NLVYQMARTT EELDRVDQNE LVSASESQTG FLPVAEKFSL KSILSPKNVE 
PSKFSGLIVN ISAGLLAALI ITVCIVAVLG REALAEGTLW AVFVMTGSVL LCMLVTGIIW 
RQPESKTKLS FKVPFVPVLP VLSIFVNIYL MMQLDQGTWV RFAVWMLIGF TIYFGYGIWH 
SEEASLAAGQ AKTPDSNLDQ CK

Genular Protein ID: 1501728899

Symbol: Q3TQZ8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TQZ8

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 476
Mass: 51085
Checksum: 7AA45C380D13125A
Sequence:

MGCKNLLGLG QQMLRRKVVD CSREESRLSR CLNTYDLVAL GVGSTLGAGV YVLAGAVARE 
NAGPAIVISF LIAALASVLA GLCYGEFGAR VPKTGSAYLY SYVTVGELWA FITGWNLILS 
YIIGTSSVAR AWSATFDELI GKPIGEFSRQ HMALNAPGVL AQTPDIFAVI IIIILTGLLT 
LGVKESAMVN KIFTCINVLV LCFIVVSGFV KGSIKNWQLT EKNFSCNNND TNVKYGEGGF 
MPFGFSGVLS GAATCFYAFV GFDCIATTGE EVKNPQKAIP VGIVASLLIC FIAYFGVSAA 
LTLMMPYFCL DIDSPLPGAF KHQGWEEAKY AVAIGSLCAL STSLLGSMFP MPRVIYAMAE 
DGLLFKFLAK INNRTKTPVI ATVTSGAIAA VMAFLFELKD LVDLMSIGTL LAYSLVAACV 
LVLRYQPEQP NLVYQMARTT EELDRVDQNE LVSASESQTG FLPVAEKFSL KSILSP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc7a1

Associated with

Other Information

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. PubMed ID: 2541919

Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. PubMed ID: 1652100

Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter. PubMed ID: 1908564

Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. PubMed ID: 9174363

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Requirement of argininosuccinate lyase for systemic nitric oxide production. PubMed ID: 22081021

The mitochondrial metallochaperone SCO1 is required to sustain expression of the high-affinity copper transporter CTR1 and preserve copper homeostasis. PubMed ID: 25683716

The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart. PubMed ID: 28973536

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073