Details for: SERPINA3

Gene ID: 12

Symbol: SERPINA3

Ensembl ID: ENSG00000196136

Description: serpin family A member 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 31.2222
    Cell Significance Index: 179.8000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 25.1073
    Cell Significance Index: -10.2000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 22.0909
    Cell Significance Index: 372.1200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 10.4740
    Cell Significance Index: -10.0000
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 10.0000
    Cell Significance Index: 98.6600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 5.4775
    Cell Significance Index: 113.6300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 3.4631
    Cell Significance Index: 80.0100
  • Cell Name: airway submucosal gland collecting duct epithelial cell (CL4033023)
    Fold Change: 3.2332
    Cell Significance Index: 22.6900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 2.3282
    Cell Significance Index: 74.5700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.2599
    Cell Significance Index: 38.0100
  • Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
    Fold Change: 2.0943
    Cell Significance Index: 13.9900
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.9596
    Cell Significance Index: 12.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.8060
    Cell Significance Index: 134.6000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.7632
    Cell Significance Index: 26.5700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.4760
    Cell Significance Index: 189.2100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 1.4237
    Cell Significance Index: 162.5100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.0532
    Cell Significance Index: 30.1900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.9722
    Cell Significance Index: 14.3500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8925
    Cell Significance Index: 19.3400
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 0.6111
    Cell Significance Index: 6.6700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.3899
    Cell Significance Index: 4.4300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2966
    Cell Significance Index: 48.2500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2735
    Cell Significance Index: 16.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.2672
    Cell Significance Index: 166.8400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.2656
    Cell Significance Index: 3.4200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2461
    Cell Significance Index: 46.8400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.2353
    Cell Significance Index: 3.6400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2329
    Cell Significance Index: 6.3400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1835
    Cell Significance Index: 23.7100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1483
    Cell Significance Index: 25.3200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1027
    Cell Significance Index: 4.6600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0838
    Cell Significance Index: 1.7900
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.0570
    Cell Significance Index: 0.4500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0564
    Cell Significance Index: 10.1700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0311
    Cell Significance Index: 3.5600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0066
    Cell Significance Index: 0.3100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0048
    Cell Significance Index: 0.2300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.0007
    Cell Significance Index: 0.0300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0050
    Cell Significance Index: -3.7200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0065
    Cell Significance Index: -12.1500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0066
    Cell Significance Index: -0.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0069
    Cell Significance Index: -3.8700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0144
    Cell Significance Index: -7.8800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0157
    Cell Significance Index: -11.8900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0197
    Cell Significance Index: -4.1400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0213
    Cell Significance Index: -2.9300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0236
    Cell Significance Index: -8.4500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0256
    Cell Significance Index: -1.0500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0326
    Cell Significance Index: -14.7900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0367
    Cell Significance Index: -4.0000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0375
    Cell Significance Index: -3.7100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0464
    Cell Significance Index: -5.7000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0516
    Cell Significance Index: -14.8500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0610
    Cell Significance Index: -12.2300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0620
    Cell Significance Index: -3.2300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0779
    Cell Significance Index: -2.2500
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: -0.0826
    Cell Significance Index: -0.5000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0836
    Cell Significance Index: -9.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0872
    Cell Significance Index: -12.6800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0878
    Cell Significance Index: -6.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1248
    Cell Significance Index: -9.5800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1280
    Cell Significance Index: -13.0800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1287
    Cell Significance Index: -3.2100
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1524
    Cell Significance Index: -3.1000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1663
    Cell Significance Index: -10.4800
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.1705
    Cell Significance Index: -2.8100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1957
    Cell Significance Index: -12.0000
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.2360
    Cell Significance Index: -3.5300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2435
    Cell Significance Index: -4.2100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2452
    Cell Significance Index: -6.1300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2502
    Cell Significance Index: -15.3800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2784
    Cell Significance Index: -7.4600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2906
    Cell Significance Index: -10.1800
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.3124
    Cell Significance Index: -2.7000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.3334
    Cell Significance Index: -5.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3429
    Cell Significance Index: -19.2400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3493
    Cell Significance Index: -18.1500
  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: -0.3495
    Cell Significance Index: -2.6700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3629
    Cell Significance Index: -11.8800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3790
    Cell Significance Index: -12.0700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3845
    Cell Significance Index: -6.4400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3915
    Cell Significance Index: -11.5300
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: -0.4157
    Cell Significance Index: -4.1600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4160
    Cell Significance Index: -10.9400
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.4264
    Cell Significance Index: -4.7100
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: -0.4549
    Cell Significance Index: -5.5000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4670
    Cell Significance Index: -12.4700
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.4678
    Cell Significance Index: -3.3600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4687
    Cell Significance Index: -20.7300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.4735
    Cell Significance Index: -4.3600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4867
    Cell Significance Index: -12.1400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.4913
    Cell Significance Index: -12.2700
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.4961
    Cell Significance Index: -6.8600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5160
    Cell Significance Index: -7.4100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5314
    Cell Significance Index: -11.0900
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.5371
    Cell Significance Index: -5.1100
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.5450
    Cell Significance Index: -5.7900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5453
    Cell Significance Index: -20.6500
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.5480
    Cell Significance Index: -3.8000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.5509
    Cell Significance Index: -7.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SERPINA3 is a serine protease inhibitor that inhibits the activity of various proteases, including chymotrypsin and trypsin. It is a small protein with a molecular weight of approximately 39 kDa and is produced by various cell types in response to inflammatory stimuli. SERPINA3 has been shown to have anti-inflammatory properties, inhibiting the activity of pro-inflammatory cytokines and enzymes. **Pathways and Functions:** SERPINA3 is involved in several key pathways, including: 1. **Acute-phase response:** SERPINA3 is induced by inflammatory stimuli, leading to the inhibition of proteases and subsequent reduction of tissue damage. 2. **Hemostasis:** SERPINA3 plays a critical role in regulating coagulation and preventing excessive clotting, thereby maintaining hemostasis. 3. **Immune response:** SERPINA3 inhibits the activity of pro-inflammatory cytokines and enzymes, promoting a resolution of inflammation. 4. **Maintenance of tissue homeostasis:** SERPINA3 regulates the activity of proteases involved in tissue repair and remodeling. **Clinical Significance:** Dysregulation of SERPINA3 has been implicated in various diseases, including: 1. **Chronic obstructive pulmonary disease (COPD):** Reduced levels of SERPINA3 have been associated with increased risk of COPD. 2. **Atherosclerosis:** SERPINA3 has been shown to inhibit the activity of proteases involved in plaque formation and instability. 3. **Cancer:** SERPINA3 has been implicated in the regulation of tumor growth and metastasis. 4. **Neurodegenerative diseases:** SERPINA3 has been shown to have neuroprotective effects, inhibiting the activity of proteases involved in neuroinflammation. In summary, SERPINA3 is a critical regulator of immune response, hemostasis, and tissue homeostasis. Its dysregulation has been implicated in various diseases, highlighting the importance of this gene in maintaining tissue health and preventing disease. Further research is needed to fully elucidate the role of SERPINA3 in human disease and to develop therapeutic strategies targeting this gene.

Genular Protein ID: 3596112924

Symbol: AACT_HUMAN

Name: Alpha-1-antichymotrypsin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 6606438

Title: Sequence homology between human alpha 1-antichymotrypsin, alpha 1-antitrypsin, and antithrombin III.

PubMed ID: 6606438

DOI: 10.1021/bi00291a001

PubMed ID: 8244391

Title: A leucine-to-proline substitution causes a defective alpha 1-antichymotrypsin allele associated with familial obstructive lung disease.

PubMed ID: 8244391

DOI: 10.1006/geno.1993.1396

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3257719

Title: Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease.

PubMed ID: 3257719

DOI: 10.1016/0092-8674(88)90462-x

PubMed ID: 9880565

Title: Molecular studies define the primary structure of alpha1-antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of act in hippocampus and liver.

PubMed ID: 9880565

DOI: 10.1074/jbc.274.3.1821

PubMed ID: 2787670

Title: The microheterogeneity of desialylated alpha 1-antichymotrypsin: the occurrence of two amino-terminal isoforms, one lacking a His-Pro dipeptide.

PubMed ID: 2787670

DOI: 10.1016/0167-4838(89)90139-8

PubMed ID: 7521171

Title: Interactions of alpha-1-antichymotrypsin, alpha-1-proteinase inhibitor, and alpha-2-macroglobulin with the fungal enzyme, seaprose.

PubMed ID: 7521171

DOI: 10.1515/bchm3.1994.375.5.335

PubMed ID: 6687683

Title: Structural alterations in alpha 1-antichymotrypsin from normal and acute phase human plasma.

PubMed ID: 6687683

DOI: 10.1016/0006-291x(83)90325-x

PubMed ID: 8647626

Title: Characterisation of the tumour-associated carbohydrate epitope recognised by monoclonal antibody 4D3.

PubMed ID: 8647626

DOI: 10.1002/(sici)1097-0215(19960529)66:5<636::aid-ijc10>3.0.co;2-2

PubMed ID: 2404007

Title: Cloning, expression, purification, and biological activity of recombinant native and variant human alpha 1-antichymotrypsins.

PubMed ID: 2404007

DOI: 10.1016/s0021-9258(19)40178-6

PubMed ID: 6547997

Title: Plasma protease inhibitors in mouse and man: divergence within the reactive centre regions.

PubMed ID: 6547997

DOI: 10.1038/311175a0

PubMed ID: 6556193

Title: Amino acid sequence at the reactive site of human alpha 1-antichymotrypsin.

PubMed ID: 6556193

DOI: 10.1016/s0021-9258(17)44026-9

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 14668352

Title: The SANT2 domain of the murine tumor cell DnaJ-like protein 1 human homologue interacts with alpha1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity.

PubMed ID: 14668352

DOI: 10.1074/jbc.m310903200

PubMed ID: 15638460

Title: Expression patterns of murine antichymotrypsin-like genes reflect evolutionary divergence at the Serpina3 locus.

PubMed ID: 15638460

DOI: 10.1007/s00239-004-2640-9

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 23234360

Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.

PubMed ID: 23234360

DOI: 10.1021/pr300963h

PubMed ID: 2016749

Title: Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7-A resolution and its comparison with other serpins.

PubMed ID: 2016749

DOI: 10.1016/0022-2836(91)90704-a

PubMed ID: 8836107

Title: Arginine substitutions in the hinge region of antichymotrypsin affect serpin beta-sheet rearrangement.

PubMed ID: 8836107

DOI: 10.1038/nsb1096-888

PubMed ID: 9521649

Title: Engineering an anion-binding cavity in antichymotrypsin modulates the 'spring-loaded' serpin-protease interaction.

PubMed ID: 9521649

DOI: 10.1021/bi972359e

PubMed ID: 10618372

Title: Inactive conformation of the serpin alpha(1)-antichymotrypsin indicates two-stage insertion of the reactive loop: implications for inhibitory function and conformational disease.

PubMed ID: 10618372

DOI: 10.1073/pnas.97.1.67

PubMed ID: 1618300

Title: Detection of a new mutant alpha-1-antichymotrypsin in patients with occlusive-cerebrovascular disease.

PubMed ID: 1618300

DOI: 10.1016/0014-5793(92)80590-d

PubMed ID: 1351206

Title: Mis-sense mutation of alpha 1-antichymotrypsin gene associated with chronic lung disease.

PubMed ID: 1351206

DOI: 10.1016/0140-6736(92)91301-n

PubMed ID: 11289720

Title: Alpha-1-antichymotrypsin gene A1252G variant (ACT Isehara-1) is associated with a lacunar type of ischemic cerebrovascular disease.

PubMed ID: 11289720

DOI: 10.1007/s100380170125

Sequence Information:

  • Length: 423
  • Mass: 47651
  • Checksum: B002F946C86A8951
  • Sequence:
  • MERMLPLLAL GLLAAGFCPA VLCHPNSPLD EENLTQENQD RGTHVDLGLA SANVDFAFSL 
    YKQLVLKAPD KNVIFSPLSI STALAFLSLG AHNTTLTEIL KGLKFNLTET SEAEIHQSFQ 
    HLLRTLNQSS DELQLSMGNA MFVKEQLSLL DRFTEDAKRL YGSEAFATDF QDSAAAKKLI 
    NDYVKNGTRG KITDLIKDLD SQTMMVLVNY IFFKAKWEMP FDPQDTHQSR FYLSKKKWVM 
    VPMMSLHHLT IPYFRDEELS CTVVELKYTG NASALFILPD QDKMEEVEAM LLPETLKRWR 
    DSLEFREIGE LYLPKFSISR DYNLNDILLQ LGIEEAFTSK ADLSGITGAR NLAVSQVVHK 
    AVLDVFEEGT EASAATAVKI TLLSALVETR TIVRFNRPFL MIIVPTDTQN IFFMSKVTNP 
    KQA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.