Details for: ADD3

Gene ID: 120

Symbol: ADD3

Ensembl ID: ENSG00000148700

Description: adducin 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 499.8546
    Cell Significance Index: -77.7500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 295.3753
    Cell Significance Index: -74.9200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 171.5974
    Cell Significance Index: -81.0200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 171.0493
    Cell Significance Index: -69.4900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 153.1343
    Cell Significance Index: -78.7700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 120.7561
    Cell Significance Index: -81.0300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 72.9516
    Cell Significance Index: -69.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 63.8709
    Cell Significance Index: -78.7500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 28.4748
    Cell Significance Index: -76.2800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 22.9077
    Cell Significance Index: -70.3600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.0758
    Cell Significance Index: -79.2200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 19.0899
    Cell Significance Index: -41.7800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 5.4598
    Cell Significance Index: 106.5600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 4.3410
    Cell Significance Index: 92.7900
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 2.7018
    Cell Significance Index: 37.7800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.5027
    Cell Significance Index: 168.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.3720
    Cell Significance Index: 850.8100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7718
    Cell Significance Index: 355.4200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.7492
    Cell Significance Index: 134.2300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.7444
    Cell Significance Index: 346.1900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.7263
    Cell Significance Index: 89.9200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.5177
    Cell Significance Index: 32.8800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.5109
    Cell Significance Index: 76.3600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4976
    Cell Significance Index: 1352.2500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.3000
    Cell Significance Index: 234.3600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.2646
    Cell Significance Index: 36.4400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.2461
    Cell Significance Index: 153.2200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.2390
    Cell Significance Index: 11.4100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.2176
    Cell Significance Index: 35.7600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.1352
    Cell Significance Index: 155.8900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.1157
    Cell Significance Index: 13.3000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.1157
    Cell Significance Index: 62.6100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9881
    Cell Significance Index: 539.6200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.9234
    Cell Significance Index: 13.2600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.8252
    Cell Significance Index: 524.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.8217
    Cell Significance Index: 53.0200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7765
    Cell Significance Index: 99.5400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.7527
    Cell Significance Index: 17.3900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.6976
    Cell Significance Index: 1313.4500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5969
    Cell Significance Index: 412.8400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5857
    Cell Significance Index: 26.5500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3783
    Cell Significance Index: 23.2500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3753
    Cell Significance Index: 44.2600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3380
    Cell Significance Index: 149.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3372
    Cell Significance Index: 21.2500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3367
    Cell Significance Index: 5.7700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.3187
    Cell Significance Index: 6.6700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3103
    Cell Significance Index: 52.9900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2477
    Cell Significance Index: 7.1000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2017
    Cell Significance Index: 19.9500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1858
    Cell Significance Index: 8.2200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1676
    Cell Significance Index: 31.8900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.1341
    Cell Significance Index: 1.9800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0686
    Cell Significance Index: 2.4100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0601
    Cell Significance Index: 3.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0145
    Cell Significance Index: 10.6500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0020
    Cell Significance Index: 3.0400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0111
    Cell Significance Index: -20.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0220
    Cell Significance Index: -13.7100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0318
    Cell Significance Index: -43.2900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0343
    Cell Significance Index: -1.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0410
    Cell Significance Index: -30.3700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0490
    Cell Significance Index: -0.8200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0571
    Cell Significance Index: -6.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0684
    Cell Significance Index: -31.0500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0784
    Cell Significance Index: -44.2200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0889
    Cell Significance Index: -67.2700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2162
    Cell Significance Index: -31.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2168
    Cell Significance Index: -45.6700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2179
    Cell Significance Index: -22.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2435
    Cell Significance Index: -70.0500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2777
    Cell Significance Index: -7.7600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2841
    Cell Significance Index: -32.4300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3208
    Cell Significance Index: -22.6900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3326
    Cell Significance Index: -42.9800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3551
    Cell Significance Index: -16.6900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3587
    Cell Significance Index: -11.4900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3895
    Cell Significance Index: -45.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3953
    Cell Significance Index: -45.2900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4036
    Cell Significance Index: -18.8200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4951
    Cell Significance Index: -14.1300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5272
    Cell Significance Index: -39.2900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5652
    Cell Significance Index: -19.6400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6703
    Cell Significance Index: -69.7900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6706
    Cell Significance Index: -9.1500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7302
    Cell Significance Index: -57.8300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7898
    Cell Significance Index: -41.4700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.7903
    Cell Significance Index: -20.7800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.8309
    Cell Significance Index: -22.1900
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.8433
    Cell Significance Index: -12.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.8653
    Cell Significance Index: -21.6300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9558
    Cell Significance Index: -58.6000
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.9569
    Cell Significance Index: -13.7600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.9932
    Cell Significance Index: -23.8200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.0061
    Cell Significance Index: -10.4200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.0410
    Cell Significance Index: -18.0000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.2783
    Cell Significance Index: -41.8500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.2929
    Cell Significance Index: -27.4400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.5006
    Cell Significance Index: -27.7400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -1.5059
    Cell Significance Index: -40.9900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** Adducin 3 is a member of the adducin family, which is composed of three isoforms (ADD1, ADD2, and ADD3). These proteins share a high degree of sequence homology and are characterized by their ability to bind actin filaments, thereby modulating cytoskeletal dynamics. ADD3 is specifically expressed in various cell types, including cardiac neurons, astrocytes, and epithelial cells, highlighting its widespread importance in maintaining cellular structure and function. **Pathways and Functions:** ADD3 is involved in multiple signaling pathways, including: 1. **Actin filament binding and capping**: ADD3 interacts with actin filaments, regulating their dynamics and stability. This interaction is crucial for maintaining cellular shape and structure. 2. **Cytoskeleton organization**: ADD3 contributes to the organization of the cytoskeleton, influencing the assembly and disassembly of actin filaments. 3. **Signaling by Rho GTPases**: ADD3 interacts with Rho GTPases, which play a critical role in regulating cytoskeletal dynamics and cell migration. 4. **Cell-cell junction**: ADD3 is involved in the formation and maintenance of cell-cell junctions, which are essential for maintaining tissue integrity. **Clinical Significance:** Adducin 3 has been implicated in various diseases, including: 1. **Cardiovascular disorders**: Alterations in ADD3 expression have been linked to cardiovascular diseases, such as heart failure and atherosclerosis. 2. **Neurological disorders**: ADD3 has been implicated in neurodegenerative diseases, including Alzheimer's and Parkinson's disease. 3. **Cancer**: Aberrant expression of ADD3 has been observed in various types of cancer, including colorectal and breast cancer. **Conclusion:** In conclusion, adducin 3 (ADD3) is a vital component of the cytoskeleton, playing a crucial role in maintaining cellular structure and function. Its involvement in multiple signaling pathways and its clinical significance make it an important target for therapeutic intervention in various diseases. Further research is needed to fully elucidate the mechanisms by which ADD3 regulates cellular processes and to explore its potential as a therapeutic target.

Genular Protein ID: 3207629938

Symbol: ADDG_HUMAN

Name: Gamma-adducin

UniProtKB Accession Codes:

Q9UEY8 D3DRA8 O43243 Q5VU09 Q92773 Q9UEY7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 32 Ensembl 3 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 7 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8893809

Title: Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adducin.

PubMed ID: 8893809

DOI: 10.1159/000134389

PubMed ID: 10581174

Title: Genomic organization of the human gamma adducin gene.

PubMed ID: 10581174

DOI: 10.1006/bbrc.1999.1769

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15561718

Title: Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.

PubMed ID: 15561718

DOI: 10.1074/jbc.m411718200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23836506

Title: Mutations in gamma adducin are associated with inherited cerebral palsy.

PubMed ID: 23836506

DOI: 10.1002/ana.23971

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 33992672

Title: A gamma-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.

PubMed ID: 33992672

DOI: 10.1016/j.pneurobio.2021.102074

Sequence Information:

  • Length: 706
  • Mass: 79155
  • Checksum: EB8EAF602A4D7B41
  • Sequence:
    • MSSDASQGVI TTPPPPSMPH KERYFDRINE NDPEYIRERN MSPDLRQDFN MMEQRKRVTQ 
ILQSPAFRED LECLIQEQMK KGHNPTGLLA LQQIADYIMA NSFSGFSSPP LSLGMVTPIN 
DLPGADTSSY VKGEKLTRCK LASLYRLVDL FGWAHLANTY ISVRISKEQD HIIIIPRGLS 
FSEATASNLV KVNIIGEVVD QGSTNLKIDH TGFSPHAAIY STRPDVKCVI HIHTLATAAV 
SSMKCGILPI SQESLLLGDV AYYDYQGSLE EQEERIQLQK VLGPSCKVLV LRNHGVVALG 
ETLEEAFHYI FNVQLACEIQ VQALAGAGGV DNLHVLDFQK YKAFTYTVAA SGGGGVNMGS 
HQKWKVGEIE FEGLMRTLDN LGYRTGYAYR HPLIREKPRH KSDVEIPATV TAFSFEDDTV 
PLSPLKYMAQ RQQREKTRWL NSPNTYMKVN VPEESRNGET SPRTKITWMK AEDSSKVSGG 
TPIKIEDPNQ FVPLNTNPNE VLEKRNKIRE QNRYDLKTAG PQSQLLAGIV VDKPPSTMQF 
EDDDHGPPAP PNPFSHLTEG ELEEYKRTIE RKQQGLEDAE QELLSDDASS VSQIQSQTQS 
PQNVPEKLEE NHELFSKSFI SMEVPVMVVN GKDDMHDVED ELAKRVSRLS TSTTIENIEI 
TIKSPEKIEE VLSPEGSPSK SPSKKKKKFR TPSFLKKNKK KEKVEA

Genular Protein ID: 3765424786

Symbol: Q59EK1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59EK1

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 698
  • Mass: 78214
  • Checksum: B9B5FC74CCD2940A
  • Sequence:
    • NMSSDASQGV ITTPPPPSMP HKERYFDRIN ENDPEYIRER NMSPDLRQDF NMMEQRKRVT 
QILQSPAFRE DLECLIQEQM KKGHNPTGLL ALQQIADYIM ANSFSGFSSP PLSLGMVTPI 
NDLPGADTSS YVKGEKLTRC KLASLYRLVD LFGWAHLANT YISVRISKEQ DHIIIIPRGL 
SFSEATASNL VKVNIIGEVV DQGSTNLKID HTGFSPHAAI YSTRPDVKCV IHIHTLATAA 
VSSMKCGILP ISQESLLLGD VAYYDYQGSL EEQEERIQLQ KVLGPSCKVL VLRNHGVVAL 
GETLEEAFHY IFNVQLACEI QVQALAGAGG VDNLHVLDFQ KYKAFTYTVA ASGGGGVNMG 
SHQKWKVGEI EFEGLMRTLD NLGYRTGYAY RHPLIREKPR HKSDVEIPAT VTAFSFEDDT 
VPLSPLKYMA QRQQREKTRW LNSPNTYMKV NVPEESRNGE TSPRTKITWM KAEDSSKVSG 
GTPIKIEDPN QFVPLNTNPN EVLEKRNKIR EQNRYDLKTA GPQSQLLAGI VVDKPPSTMQ 
FEDDDHGPPA PPNPFSHLTE GELEEYKRTI ERKQQGLEDA EQELLSDDAS SVSQIQSQTQ 
SPQNVPEKLE ENHELFSKSF ISMEVPVMVV NGKDDMHDVE DELAKRVSRL STSTTIENIE 
ITIKSPEKIE EVLSPEGSPS KSPSKKKKKF RTPSFLKK

Genular Protein ID: 2640550667

Symbol: Q53FL4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53FL4

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 1 RefSeq 3 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 667
  • Mass: 74480
  • Checksum: 7592D5051AA38371
  • Sequence:
    • NMSPDLRQDF NMMEQRKRVT QILQSPAFRE DLECLIQEQM KKGHNPTGLL ALQQIADYIM 
ANSFSGSSSP PLSLGMVTPI NDLPGADTSS YVKGEKLTRC KLASLYRLVD LFGWAHLANT 
YISVRISKEQ DHIIIIPRGL SFSEATASNL VKVNIIGEVV DQGSTNLKID HTGFSPHAAI 
YSTRPDVKCV IHIHTLATAA VSSMKCGILP ISQESLLLGD VAYYDYQGSL EEQEERTQLQ 
KVLGPSCKVL VLRNHGVVAL GETLEEAFHY IFNVQLACEI QVQALAGAGG VDNLHVLDFQ 
KYKAFTYTVA ASGGGGVNMG SHQKWKVGEI EFEGLMRTLD NLGYRTGYAY RHPLIREKPR 
HKSVVEIPAT VTAFSFEDDT VPLSPLKYMA QRQQREKTRW LNSPNTYMKV NVPEESRNGE 
TSPRTKITWM KAEDSSKVSG GTPIKIEDPN QFVPLNTNPN EVLEKRNKIR EQNRYDLKTA 
GPQSQLLAGI VVDKPPSTMQ FEDDDHGPPA PPNPFSHLTE GELEEYKRTI ERKQQGLEDA 
EQELLSDDAS SVSQIQSQTQ SPQNVPEKLE ENHELFSKSF ISMEVPVMVV NGKDDMHDGE 
DELAKRVSRL STSTTIENIE ITIKSPEKIE EVLSPEGSPS KSPSKKKKKF RTPSFLKKNK 
KKEKVEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.