Details for: ADD3

Gene ID: 120

Symbol: ADD3

Ensembl ID: ENSG00000148700

Description: adducin 3

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 3.47
    Marker Score: 4,317
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.09
    Marker Score: 65,936
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.82
    Marker Score: 825
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.75
    Marker Score: 1,812
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.74
    Marker Score: 1,596
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.72
    Marker Score: 11,399
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.66
    Marker Score: 140,541
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.52
    Marker Score: 10,517
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.52
    Marker Score: 1,243
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 2.51
    Marker Score: 1,774
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.5
    Marker Score: 2,165
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.46
    Marker Score: 28,591
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 2.42
    Marker Score: 2,094
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.34
    Marker Score: 4,510
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.32
    Marker Score: 9,936
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.23
    Marker Score: 7,030
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.21
    Marker Score: 32,970
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.19
    Marker Score: 5,252
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 2.18
    Marker Score: 942
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 2.16
    Marker Score: 496
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 2.14
    Marker Score: 4,191
  • Cell Name: podocyte (CL0000653)
    Fold Change: 2.14
    Marker Score: 790
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.12
    Marker Score: 42,267
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.12
    Marker Score: 2,621
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.1
    Marker Score: 77,489
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 2.08
    Marker Score: 2,012
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.08
    Marker Score: 8,041
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.07
    Marker Score: 6,771
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 2.06
    Marker Score: 682
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.06
    Marker Score: 2,370
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.05
    Marker Score: 45,835
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 2.03
    Marker Score: 1,269
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.02
    Marker Score: 5,767
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.02
    Marker Score: 1,771
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.98
    Marker Score: 691
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.97
    Marker Score: 2,779
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.97
    Marker Score: 1,439
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 1.95
    Marker Score: 2,704
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.95
    Marker Score: 1,822
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.94
    Marker Score: 12,418
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.93
    Marker Score: 18,177
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.92
    Marker Score: 2,021
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 1.89
    Marker Score: 1,387
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.89
    Marker Score: 12,054
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.88
    Marker Score: 7,786
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 1.87
    Marker Score: 4,561
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.86
    Marker Score: 2,181
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.86
    Marker Score: 700
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.86
    Marker Score: 4,868
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.85
    Marker Score: 4,971
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.84
    Marker Score: 16,186
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.83
    Marker Score: 6,492
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.83
    Marker Score: 69,369
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.83
    Marker Score: 1,268
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.83
    Marker Score: 4,604
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.82
    Marker Score: 15,666
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.82
    Marker Score: 2,808
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.82
    Marker Score: 449
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.79
    Marker Score: 610
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.79
    Marker Score: 60,990
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.77
    Marker Score: 1,882
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.77
    Marker Score: 1,908
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.76
    Marker Score: 3,075
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.76
    Marker Score: 1,769
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.75
    Marker Score: 875
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.75
    Marker Score: 1,026
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.75
    Marker Score: 1,054
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.74
    Marker Score: 7,090
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.74
    Marker Score: 4,722
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.72
    Marker Score: 3,628
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.72
    Marker Score: 608
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 1.72
    Marker Score: 2,528
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 1.71
    Marker Score: 22,611
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 1.71
    Marker Score: 2,938
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.71
    Marker Score: 4,067
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.71
    Marker Score: 13,093
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.7
    Marker Score: 1,566
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.7
    Marker Score: 1,679
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.7
    Marker Score: 2,346
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.7
    Marker Score: 1,136
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7
    Marker Score: 104,488
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 1.7
    Marker Score: 619
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.69
    Marker Score: 684
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.69
    Marker Score: 1,607
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.68
    Marker Score: 2,377
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.67
    Marker Score: 7,217
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 1.67
    Marker Score: 1,570
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 1.67
    Marker Score: 1,365
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.66
    Marker Score: 3,757
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.65
    Marker Score: 429
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.65
    Marker Score: 491
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.64
    Marker Score: 2,412
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 1.63
    Marker Score: 1,355
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.63
    Marker Score: 1,253
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.62
    Marker Score: 4,039
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.61
    Marker Score: 812
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 1.61
    Marker Score: 1,734
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 1.6
    Marker Score: 1,252
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.6
    Marker Score: 387
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.59
    Marker Score: 994

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** Adducin 3 is a member of the adducin family, which is composed of three isoforms (ADD1, ADD2, and ADD3). These proteins share a high degree of sequence homology and are characterized by their ability to bind actin filaments, thereby modulating cytoskeletal dynamics. ADD3 is specifically expressed in various cell types, including cardiac neurons, astrocytes, and epithelial cells, highlighting its widespread importance in maintaining cellular structure and function. **Pathways and Functions:** ADD3 is involved in multiple signaling pathways, including: 1. **Actin filament binding and capping**: ADD3 interacts with actin filaments, regulating their dynamics and stability. This interaction is crucial for maintaining cellular shape and structure. 2. **Cytoskeleton organization**: ADD3 contributes to the organization of the cytoskeleton, influencing the assembly and disassembly of actin filaments. 3. **Signaling by Rho GTPases**: ADD3 interacts with Rho GTPases, which play a critical role in regulating cytoskeletal dynamics and cell migration. 4. **Cell-cell junction**: ADD3 is involved in the formation and maintenance of cell-cell junctions, which are essential for maintaining tissue integrity. **Clinical Significance:** Adducin 3 has been implicated in various diseases, including: 1. **Cardiovascular disorders**: Alterations in ADD3 expression have been linked to cardiovascular diseases, such as heart failure and atherosclerosis. 2. **Neurological disorders**: ADD3 has been implicated in neurodegenerative diseases, including Alzheimer's and Parkinson's disease. 3. **Cancer**: Aberrant expression of ADD3 has been observed in various types of cancer, including colorectal and breast cancer. **Conclusion:** In conclusion, adducin 3 (ADD3) is a vital component of the cytoskeleton, playing a crucial role in maintaining cellular structure and function. Its involvement in multiple signaling pathways and its clinical significance make it an important target for therapeutic intervention in various diseases. Further research is needed to fully elucidate the mechanisms by which ADD3 regulates cellular processes and to explore its potential as a therapeutic target.

Genular Protein ID: 3207629938

Symbol: ADDG_HUMAN

Name: Gamma-adducin

UniProtKB Accession Codes:

Q9UEY8 D3DRA8 O43243 Q5VU09 Q92773 Q9UEY7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 32 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 7 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8893809

Title: Cloning, expression and chromosome mapping of adducin-like 70 (ADDL), a human cDNA highly homologous to human erythrocyte adducin.

PubMed ID: 8893809

DOI: 10.1159/000134389

PubMed ID: 10581174

Title: Genomic organization of the human gamma adducin gene.

PubMed ID: 10581174

DOI: 10.1006/bbrc.1999.1769

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15561718

Title: Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.

PubMed ID: 15561718

DOI: 10.1074/jbc.m411718200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23836506

Title: Mutations in gamma adducin are associated with inherited cerebral palsy.

PubMed ID: 23836506

DOI: 10.1002/ana.23971

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 33992672

Title: A gamma-adducin cleavage fragment induces neurite deficits and synaptic dysfunction in Alzheimer's disease.

PubMed ID: 33992672

DOI: 10.1016/j.pneurobio.2021.102074

Sequence Information:

  • Length: 706
  • Mass: 79155
  • Checksum: EB8EAF602A4D7B41
  • Sequence:
    • MSSDASQGVI TTPPPPSMPH KERYFDRINE NDPEYIRERN MSPDLRQDFN MMEQRKRVTQ 
ILQSPAFRED LECLIQEQMK KGHNPTGLLA LQQIADYIMA NSFSGFSSPP LSLGMVTPIN 
DLPGADTSSY VKGEKLTRCK LASLYRLVDL FGWAHLANTY ISVRISKEQD HIIIIPRGLS 
FSEATASNLV KVNIIGEVVD QGSTNLKIDH TGFSPHAAIY STRPDVKCVI HIHTLATAAV 
SSMKCGILPI SQESLLLGDV AYYDYQGSLE EQEERIQLQK VLGPSCKVLV LRNHGVVALG 
ETLEEAFHYI FNVQLACEIQ VQALAGAGGV DNLHVLDFQK YKAFTYTVAA SGGGGVNMGS 
HQKWKVGEIE FEGLMRTLDN LGYRTGYAYR HPLIREKPRH KSDVEIPATV TAFSFEDDTV 
PLSPLKYMAQ RQQREKTRWL NSPNTYMKVN VPEESRNGET SPRTKITWMK AEDSSKVSGG 
TPIKIEDPNQ FVPLNTNPNE VLEKRNKIRE QNRYDLKTAG PQSQLLAGIV VDKPPSTMQF 
EDDDHGPPAP PNPFSHLTEG ELEEYKRTIE RKQQGLEDAE QELLSDDASS VSQIQSQTQS 
PQNVPEKLEE NHELFSKSFI SMEVPVMVVN GKDDMHDVED ELAKRVSRLS TSTTIENIEI 
TIKSPEKIEE VLSPEGSPSK SPSKKKKKFR TPSFLKKNKK KEKVEA

Genular Protein ID: 3765424786

Symbol: Q59EK1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59EK1

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 Gene3D 1 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 698
  • Mass: 78214
  • Checksum: B9B5FC74CCD2940A
  • Sequence:
    • NMSSDASQGV ITTPPPPSMP HKERYFDRIN ENDPEYIRER NMSPDLRQDF NMMEQRKRVT 
QILQSPAFRE DLECLIQEQM KKGHNPTGLL ALQQIADYIM ANSFSGFSSP PLSLGMVTPI 
NDLPGADTSS YVKGEKLTRC KLASLYRLVD LFGWAHLANT YISVRISKEQ DHIIIIPRGL 
SFSEATASNL VKVNIIGEVV DQGSTNLKID HTGFSPHAAI YSTRPDVKCV IHIHTLATAA 
VSSMKCGILP ISQESLLLGD VAYYDYQGSL EEQEERIQLQ KVLGPSCKVL VLRNHGVVAL 
GETLEEAFHY IFNVQLACEI QVQALAGAGG VDNLHVLDFQ KYKAFTYTVA ASGGGGVNMG 
SHQKWKVGEI EFEGLMRTLD NLGYRTGYAY RHPLIREKPR HKSDVEIPAT VTAFSFEDDT 
VPLSPLKYMA QRQQREKTRW LNSPNTYMKV NVPEESRNGE TSPRTKITWM KAEDSSKVSG 
GTPIKIEDPN QFVPLNTNPN EVLEKRNKIR EQNRYDLKTA GPQSQLLAGI VVDKPPSTMQ 
FEDDDHGPPA PPNPFSHLTE GELEEYKRTI ERKQQGLEDA EQELLSDDAS SVSQIQSQTQ 
SPQNVPEKLE ENHELFSKSF ISMEVPVMVV NGKDDMHDVE DELAKRVSRL STSTTIENIE 
ITIKSPEKIE EVLSPEGSPS KSPSKKKKKF RTPSFLKK

Genular Protein ID: 2640550667

Symbol: Q53FL4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53FL4

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 Gene3D 1 GenomeRNAi 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 1 RefSeq 3 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 667
  • Mass: 74480
  • Checksum: 7592D5051AA38371
  • Sequence:
    • NMSPDLRQDF NMMEQRKRVT QILQSPAFRE DLECLIQEQM KKGHNPTGLL ALQQIADYIM 
ANSFSGSSSP PLSLGMVTPI NDLPGADTSS YVKGEKLTRC KLASLYRLVD LFGWAHLANT 
YISVRISKEQ DHIIIIPRGL SFSEATASNL VKVNIIGEVV DQGSTNLKID HTGFSPHAAI 
YSTRPDVKCV IHIHTLATAA VSSMKCGILP ISQESLLLGD VAYYDYQGSL EEQEERTQLQ 
KVLGPSCKVL VLRNHGVVAL GETLEEAFHY IFNVQLACEI QVQALAGAGG VDNLHVLDFQ 
KYKAFTYTVA ASGGGGVNMG SHQKWKVGEI EFEGLMRTLD NLGYRTGYAY RHPLIREKPR 
HKSVVEIPAT VTAFSFEDDT VPLSPLKYMA QRQQREKTRW LNSPNTYMKV NVPEESRNGE 
TSPRTKITWM KAEDSSKVSG GTPIKIEDPN QFVPLNTNPN EVLEKRNKIR EQNRYDLKTA 
GPQSQLLAGI VVDKPPSTMQ FEDDDHGPPA PPNPFSHLTE GELEEYKRTI ERKQQGLEDA 
EQELLSDDAS SVSQIQSQTQ SPQNVPEKLE ENHELFSKSF ISMEVPVMVV NGKDDMHDGE 
DELAKRVSRL STSTTIENIE ITIKSPEKIE EVLSPEGSPS KSPSKKKKKF RTPSFLKKNK 
KKEKVEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.