Genular: Defining Cellular Identity and Function

Details for: Bach2

Gene ID: 12014

Symbol: Bach2

Ensembl ID: ENSMUSG00000040270

Description: BTB and CNC homology, basic leucine zipper transcription factor 2

Associated with

Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Import into nucleus
(GO:0051170)
Ion binding
(GO:0043167)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Primary adaptive immune response involving t cells and b cells
(GO:0090721)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Sequence-specific double-stranded dna binding
(GO:1990837)

Other Information

Proteins

Transcription regulator protein BACH2

Genular Protein ID: 2473308892

Symbol: BACH2_MOUSE

Name: Transcription regulator protein BACH2

UniProtKB Accession Codes:

P97303 A2ANU8 A2ANU9 A2RRI0

Database IDs:

Citations:

PubMed ID: 8887638

Title: Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.

PubMed ID: 8887638

DOI: 10.1128/mcb.16.11.6083

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10809773

Title: Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element.

PubMed ID: 10809773

DOI: 10.1074/jbc.275.20.15370

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26021350

Title: Genome-wide RNAi screen for nuclear actin reveals a network of cofilin regulators.

PubMed ID: 26021350

DOI: 10.1242/jcs.169441

PubMed ID: 28530713

Title: BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.

PubMed ID: 28530713

DOI: 10.1038/ni.3753

Sequence Information:

Length: 839
Mass: 91836
Checksum: 8A5321A68A07653D
Sequence:

MSVDEKPGSP MYVYESTVHC ANILLGLNDQ RKKDILCDVT LIVERKEFRA HRAVLAACSE 
YFWQALVGQT KDDLVVSLPE EVTARGFGPL LQFAYTAKLL LSRENIREVI RCAEFLRMHN 
LEDSCFSFLQ TQLLNREDGL FVCRKDSACQ RPQEDHGNSA GEEEEEEETM DSETARMACA 
TDQMLPDPIS FEATAIPVAE KEEALLPESE VPTDTKENSE KGALTQYPRY KKYQLACTKN 
VYSAPSHGTS GFASTFSEDS PGNSLKPGLP MGQIKSEPPS EETEEESITL CLSGDETDIK 
DRPGDVEMDR KQPSPAPTPS TPTGAACLDR SRSVSSPSCL RSLFGITKGV ESTGLPSTSQ 
QPLVRSSACP FNKGISQGDL KTDYTPLAGN YGQPHVGQKD VSNFAMGSPL RGPGPETLCK 
QEGELDRRSV IFSASACDQP NTPVHSYSAV SNLDKDLSEP VPKSLWVGAG QSLPSSQAYS 
HSGLMADHLP GRIRPNTSCP VPIKVCPRSP PLETRTRTSS SCSSYSYAED GSGGSPCSLP 
LCEFSSSPCS QGARFLATEH QEPGLMGDGM YNQVRPQIKC EQSYGTNSSD ESGSFSEADS 
ESCPVQDRGQ EVKLPFPVDQ ITDLPRNDFQ MMIKMHKLTS EQLEFIHDIR RRSKNRIAAQ 
RCRKRKLDCI QNLECEIRKL VCEKEKLLSE RNHLKACMGE LLDNFSCLSQ EVCRDIQSPE 
QIQALHRYCP VLIPMDLPGA SVNPPPVGVE QSLAPSPCAV GGSVPCCLEP GAAPPGLPWV 
PSNTSENCTS GRRLEGSDPG TFSERGPPLE ARSQSVTVDF CQEMTEKCTT DEQPRKDYA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bach2

Associated with

Other Information

Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. PubMed ID: 8887638

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Oxidative stress abolishes leptomycin B-sensitive nuclear export of transcription repressor Bach2 that counteracts activation of Maf recognition element. PubMed ID: 10809773

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Genome-wide RNAi screen for nuclear actin reveals a network of cofilin regulators. PubMed ID: 26021350

BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency. PubMed ID: 28530713