Genular: Defining Cellular Identity and Function

Details for: Nkx3 2

Gene ID: 12020

Symbol: Nkx3 2

Ensembl ID: ENSMUSG00000049691

Description: NK3 homeobox 2

Associated with

Animal organ development
(GO:0048513)
Animal organ formation
(GO:0048645)
Cell differentiation
(GO:0030154)
Determination of left/right symmetry
(GO:0007368)
Digestive system development
(GO:0055123)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Embryonic skeletal system development
(GO:0048706)
Intestinal epithelial cell development
(GO:0060576)
Middle ear morphogenesis
(GO:0042474)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of chondrocyte differentiation
(GO:0032331)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pancreas development
(GO:0031016)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific double-stranded dna binding
(GO:1990837)
Skeletal system development
(GO:0001501)
Skeletal system morphogenesis
(GO:0048705)
Spleen development
(GO:0048536)

Other Information

Proteins

Homeobox protein Nkx-3.2

Genular Protein ID: 2634101079

Symbol: NKX32_MOUSE

Name: Homeobox protein Nkx-3.2

UniProtKB Accession Codes:

P97503 A6H6G9

Database IDs:

Citations:

PubMed ID: 9256352

Title: Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton.

PubMed ID: 9256352

DOI: 10.1016/s0925-4773(97)00067-1

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14973294

Title: Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution.

PubMed ID: 14973294

DOI: 10.1242/dev.01017

PubMed ID: 16421188

Title: Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation.

PubMed ID: 16421188

DOI: 10.1242/dev.02258

PubMed ID: 19208343

Title: Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development.

PubMed ID: 19208343

DOI: 10.1053/j.gastro.2009.01.009

Sequence Information:

Length: 333
Mass: 35167
Checksum: D089523714C86BA6
Sequence:

MAVRGSGTLT PFSIQAILNK KEERGGLATP EGRPAPGGTE VAVTAAPAVC CWRIFGETEA 
GALGGAEDSL LASPARTRTA VGQSAESPGG WDSDSALSEE NEGRRRCADV PGASGTGRAR 
VTLGLDQPGC ELHAAKDLEE EAPVRSDSEM SASVSGDHSP RGEDDSVSPG GARVPGLRGA 
AGSGASGGQA GGVEEEEEPA APKPRKKRSR AAFSHAQVFE LERRFNHQRY LSGPERADLA 
ASLKLTETQV KIWFQNRRYK TKRRQMAADL LASAPAAKKV AVKVLVRDDQ RQYLPGEVLR 
PPSLLPLQPS YYYPYYCLPG WALSTCAAAA GTQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nkx3 2

Associated with

Other Information

Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton. PubMed ID: 9256352

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution. PubMed ID: 14973294