Genular: Defining Cellular Identity and Function

Details for: Bard1

Gene ID: 12021

Symbol: Bard1

Ensembl ID: ENSMUSG00000026196

Description: BRCA1 associated RING domain 1

Associated with

Cell cycle
(R-MMU-1640170)
Cell cycle checkpoints
(R-MMU-69620)
Deubiquitination
(R-MMU-5688426)
Dna double-strand break repair
(R-MMU-5693532)
Dna double strand break response
(R-MMU-5693606)
G2/m checkpoints
(R-MMU-69481)
G2/m dna damage checkpoint
(R-MMU-69473)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hdr through homologous recombination (hrr)
(R-MMU-5685942)
Hdr through homologous recombination (hrr) or single strand annealing (ssa)
(R-MMU-5693567)
Hdr through single strand annealing (ssa)
(R-MMU-5685938)
Homologous dna pairing and strand exchange
(R-MMU-5693579)
Homology directed repair
(R-MMU-5693538)
Metabolism of proteins
(R-MMU-392499)
Metalloprotease dubs
(R-MMU-5689901)
Nonhomologous end-joining (nhej)
(R-MMU-5693571)
Post-translational protein modification
(R-MMU-597592)
Presynaptic phase of homologous dna pairing and strand exchange
(R-MMU-5693616)
Processing of dna double-strand break ends
(R-MMU-5693607)
Recruitment and atm-mediated phosphorylation of repair and signaling proteins at dna double strand breaks
(R-MMU-5693565)
Regulation of tp53 activity
(R-MMU-5633007)
Regulation of tp53 activity through phosphorylation
(R-MMU-6804756)
Resolution of d-loop structures
(R-MMU-5693537)
Resolution of d-loop structures through holliday junction intermediates
(R-MMU-5693568)
Rna polymerase ii transcription
(R-MMU-73857)
Transcriptional regulation by tp53
(R-MMU-3700989)
Uch proteinases
(R-MMU-5689603)
Brca1-a complex
(GO:0070531)
Brca1-bard1 complex
(GO:0031436)
Brca1-b complex
(GO:0070532)
Brca1-c complex
(GO:0070533)
Cellular response to ionizing radiation
(GO:0071479)
Cytoplasm
(GO:0005737)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Dna strand resection involved in replication fork processing
(GO:0110025)
Homologous recombination
(GO:0035825)
Metal ion binding
(GO:0046872)
Mitotic g2/m transition checkpoint
(GO:0044818)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of protein export from nucleus
(GO:0046826)
Nuclear speck
(GO:0016607)
Nuclear ubiquitin ligase complex
(GO:0000152)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell cycle
(GO:0045787)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Protein k6-linked ubiquitination
(GO:0085020)
Regulation of dna damage checkpoint
(GO:2000001)
Regulation of dna repair
(GO:0006282)
Regulation of phosphorylation
(GO:0042325)
Rna binding
(GO:0003723)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activity
(GO:0004842)

Other Information

Proteins

BRCA1-associated RING domain protein 1

Genular Protein ID: 3453501445

Symbol: BARD1_MOUSE

Name: BRCA1-associated RING domain protein 1

UniProtKB Accession Codes:

O70445 A2VCQ1

Database IDs:

Citations:

PubMed ID: 9798686

Title: Conservation of function and primary structure in the BRCA1-associated RING domain (BARD1) protein.

PubMed ID: 9798686

DOI: 10.1038/sj.onc.1202123

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15077185

Title: Nuclear-cytoplasmic translocation of BARD1 is linked to its apoptotic activity.

PubMed ID: 15077185

DOI: 10.1038/sj.onc.1207427

Sequence Information:

Length: 765
Mass: 84254
Checksum: C43DD0625F2F1AE9
Sequence:

MPRRPPRVCS GNQPAPVPAM EPATDGLWAH SRAALARLEK LLRCSRCANI LKEPVCLGGC 
EHIFCSGCIS DCVGSGCPVC YTPAWILDLK INRQLDSMIQ LSSKLQNLLH DNKDSKDNTS 
RASLFGDAER KKNSIKMWFS PRSKKVRYVV TKVSVQTQPQ KAKDDKAQEA SMYEFVSATP 
PVAVPKSAKT ASRTSAKKHP KKSVAKINRE ENLRPETKDS RFDSKEELKE EKVVSCSQIP 
VMERPRVNGE IDLLASGSVV EPECSGSLTE VSLPLAEHIV SPDTVSKNEE TPEKKVCVKD 
LRSGGSNGNR KGCHRPTTST SDSCGSNIPS TSRGIGEPAL LAENVVLVDC SSLPSGQLQV 
DVTLRRKSNA SDDPLSLSPG TPPPLLNNST HRQMMSSPST VKLSSGMPAR KRNHRGETLL 
HIASIKGDIP SVEYLLQNGN DPNVKDHAGW TPLHEACSHG HLKVVELLLQ HNALVNTPGY 
QNDSPLHDAV KSGHIDIVKV LLSHGASRNA VNIFGVRPVD YTDNENIRSL LLLPEENESF 
STSQCSIVNT GQRKNGPLVF IGSGLSSQQQ KMLSKLETVL KAKKCMEFDS TVTHVIVPDE 
EAQSTLKCML GILSGCWILK FDWVKACLDS KVREQEEKYE VPGGPQRSRL NREQLLPKLF 
DGCYFFLGGN FKHHPRDDLL KLIAAAGGKV LSRKPKPDSD VTQTINTVAY HAKPESDQRF 
CTQYIVYEDL FNCHPERVRQ GKVWMAPSTW LISCIMAFEL LPLDS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.