Genular: Defining Cellular Identity and Function

Details for: Bcan

Gene ID: 12032

Symbol: Bcan

Ensembl ID: ENSMUSG00000004892

Description: brevican

Associated with

A tetrasaccharide linker sequence is required for gag synthesis
(R-MMU-1971475)
Chondroitin sulfate/dermatan sulfate metabolism
(R-MMU-1793185)
Chondroitin sulfate biosynthesis
(R-MMU-2022870)
Cs/ds degradation
(R-MMU-2024101)
Degradation of the extracellular matrix
(R-MMU-1474228)
Dermatan sulfate biosynthesis
(R-MMU-2022923)
Ecm proteoglycans
(R-MMU-3000178)
Extracellular matrix organization
(R-MMU-1474244)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Heparan sulfate/heparin (hs-gag) metabolism
(R-MMU-1638091)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Axon
(GO:0030424)
Axon initial segment
(GO:0043194)
Calcium ion binding
(GO:0005509)
Carbohydrate binding
(GO:0030246)
Cell-matrix adhesion
(GO:0007160)
Cell adhesion
(GO:0007155)
Cell surface
(GO:0009986)
Central nervous system development
(GO:0007417)
Dendrite
(GO:0030425)
Extracellular matrix
(GO:0031012)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Gaba-ergic synapse
(GO:0098982)
Glial cell differentiation
(GO:0010001)
Glutamatergic synapse
(GO:0098978)
Hippocampus development
(GO:0021766)
Hyaluronic acid binding
(GO:0005540)
Neuron projection extension
(GO:1990138)
Node of ranvier
(GO:0033268)
Perineuronal net
(GO:0072534)
Perisynaptic extracellular matrix
(GO:0098966)
Positive regulation of neuroblast proliferation
(GO:0002052)
Skeletal system development
(GO:0001501)
Synapse
(GO:0045202)
Synapse maturation
(GO:0060074)
Synaptic membrane
(GO:0097060)

Other Information

Proteins

Brevican core protein
Q3TSQ8_MOUSE

Genular Protein ID: 2044756297

Symbol: PGCB_MOUSE

Name: Brevican core protein

UniProtKB Accession Codes:

Q61361 Q80WT7

Database IDs:

Citations:

PubMed ID: 9286696

Title: Sequence and chromosomal localization of the mouse brevican gene.

PubMed ID: 9286696

DOI: 10.1006/geno.1997.4853

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14550776

Title: Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets.

PubMed ID: 14550776

DOI: 10.1016/s1044-7431(03)00133-7

PubMed ID: 17114649

Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PubMed ID: 17114649

DOI: 10.1074/mcp.m600046-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22121037

Title: Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum.

PubMed ID: 22121037

DOI: 10.1002/cne.23009

PubMed ID: 29777959

Title: Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix.

PubMed ID: 29777959

DOI: 10.1016/j.actbio.2018.05.023

Sequence Information:

Length: 883
Mass: 95815
Checksum: 64DDE4D951D2042A
Sequence:

MIPLLLSLLA ALVLTQAPAA LADDLKEDSS EDRAFRVRIG ATQLRGVLGG ALAIPCHVHH 
LRPPHSRRAA PGFPRVKWTF LSGDREVEVL VARGLRVKVN EAYRFRVALP AYPASLTDVS 
LVLSELRPND SGVYRCEVQH GIDDSSDAVE VKVKGVVFLY REGSARYAFS FAGAQEACAR 
IGARIATPEQ LYAAYLGGYE QCDAGWLSDQ TVRYPIQNPR EACSGDMDGY PGVRNYGVVG 
PDDLYDVYCY AEDLNGELFL GAPPSKLTWE EARDYCLERG AQIASTGQLY AAWNGGLDRC 
SPGWLADGSV RYPIITPSQR CGGGLPGVKT LFLFPNQTGF PSKQNRFNVY CFRDSAHPSA 
SSEASSPASD GLEAIVTVTE KLEELQLPQE AMESESRGAI YSIPISEDGG GGSSTPEDPA 
EAPRTPLESE TQSIAPPTES SEEEGVALEE EERFKDLEAL EEEKEQEDLW VWPRELSSPL 
PTGSETEHSL SQVSPPAQAV LQLGASPSPG PPRVRGPPAE TLLPPREGSP TSTPGGAREV 
GGETGSPELS GVPRESEEAG SSSLEDGPSL LPATWAPVGP RELETPSEEK SGRTVLAGTS 
VQAQPVLPTD SASHGGVAVA PSSGDCIPSP CHNGGTCLEE KEGFRCLCLP GYGGDLCDVG 
LHFCSPGWEA FQGACYKHFS TRRSWEEAES QCRALGAHLT SICTPEEQDF VNDRYREYQW 
IGLNDRTIEG DFLWSDGAPL LYENWNPGQP DSYFLSGENC VVMVWHDQGQ WSDVPCNYHL 
SYTCKMGLVS CGPPPQLPLA QIFGRPRLRY AVDTVLRYRC RDGLAQRNLP LIRCQENGLW 
EAPQISCVPR RPGRALRSMD APEGPRGQLS RHRKAPLTPP SSL

Genular Protein ID: 3379927172

Symbol: Q3TSQ8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TSQ8

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 299
Mass: 31125
Checksum: 275671783DCDC0B3
Sequence:

FNVYCFRDSA HPSASSEASS PASDGLEAIV TVTEKLEELQ LPQEAMESES RGAIYSIPIS 
EDGGGGSSTP EDPAEAPRTP LESETQSIAP PTESSEEEGV ALEEEERFKD LEALEEEKEQ 
EDLWVWPREL SSPLPTGSET EHSLSQVSPP AQAVLQLGAS PSPGPPRVRG PPAETLLPPR 
EGSPTSTPGG AREVGGETGS PELSGVPRES EEAGSSSLED GPSLLPATWA PVGPRELETP 
SEEKSGRTVL AGTSVQAQPV LPTDSASHGG VAVAPSSGNS AEGSMPAFLL FLLLQLWAT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bcan

Associated with

Other Information

Sequence and chromosomal localization of the mouse brevican gene. PubMed ID: 9286696

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets. PubMed ID: 14550776

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. PubMed ID: 17114649

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum. PubMed ID: 22121037

Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix. PubMed ID: 29777959

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073