Bcl2l1 | ENSMUSG00000007659 | NCBI 12048

Details for: Bcl2l1

Gene ID: 12048

Symbol: Bcl2l1

Ensembl ID: ENSMUSG00000007659

Description: BCL2-like 1

Associated with

Apoptosis
(R-MMU-109581)
Bh3-only proteins associate with and inactivate anti-apoptotic bcl-2 members
(R-MMU-111453)
Immune system
(R-MMU-168256)
Inflammasomes
(R-MMU-622312)
Innate immune system
(R-MMU-168249)
Intrinsic pathway for apoptosis
(R-MMU-109606)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways
(R-MMU-168643)
Programmed cell death
(R-MMU-5357801)
Raf/map kinase cascade
(R-MMU-5673001)
Ras processing
(R-MMU-9648002)
Signal transduction
(R-MMU-162582)
The nlrp1 inflammasome
(R-MMU-844455)
Apoptotic process
(GO:0006915)
Apoptotic process in bone marrow cell
(GO:0071839)
Bh3 domain binding
(GO:0051434)
Bh domain binding
(GO:0051400)
Cellular response to alkaloid
(GO:0071312)
Cellular response to amino acid stimulus
(GO:0071230)
Cellular response to gamma radiation
(GO:0071480)
Clathrin binding
(GO:0030276)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process
(GO:0043027)
Cytoplasm
(GO:0005737)
Defense response to virus
(GO:0051607)
Dendritic cell apoptotic process
(GO:0097048)
Dendritic cell proliferation
(GO:0044565)
Ectopic germ cell programmed cell death
(GO:0035234)
Epithelial cell proliferation
(GO:0050673)
Extrinsic apoptotic signaling pathway in absence of ligand
(GO:0097192)
Fertilization
(GO:0009566)
Germ cell development
(GO:0007281)
Gtpase binding
(GO:0051020)
Hepatocyte apoptotic process
(GO:0097284)
Identical protein binding
(GO:0042802)
Intracellular anatomical structure
(GO:0005622)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
In utero embryonic development
(GO:0001701)
Male gonad development
(GO:0008584)
Mdm2/mdm4 family protein binding
(GO:0097371)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Mitochondrion organization
(GO:0007005)
Negative regulation of anoikis
(GO:2000811)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dendritic cell apoptotic process
(GO:2000669)
Negative regulation of developmental process
(GO:0051093)
Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
(GO:1902236)
Negative regulation of execution phase of apoptosis
(GO:1900118)
Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
(GO:1902042)
Negative regulation of intrinsic apoptotic signaling pathway
(GO:2001243)
Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage
(GO:1902230)
Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
(GO:1901029)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of protein localization to plasma membrane
(GO:1903077)
Negative regulation of release of cytochrome c from mitochondria
(GO:0090201)
Negative regulation of reproductive process
(GO:2000242)
Neuron apoptotic process
(GO:0051402)
Nucleus
(GO:0005634)
Ovarian follicle development
(GO:0001541)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of atp biosynthetic process
(GO:2001171)
Positive regulation of mononuclear cell proliferation
(GO:0032946)
Positive regulation of synaptic vesicle clustering
(GO:2000809)
Positive regulation of synaptic vesicle endocytosis
(GO:1900244)
Positive regulation of synaptic vesicle exocytosis
(GO:2000302)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Protein kinase binding
(GO:0019901)
Regulation of apoptotic process
(GO:0042981)
Regulation of cytokinesis
(GO:0032465)
Regulation of growth
(GO:0040008)
Regulation of long-term synaptic depression
(GO:1900452)
Regulation of mitochondrial membrane permeability
(GO:0046902)
Regulation of mitochondrial membrane potential
(GO:0051881)
Release of cytochrome c from mitochondria
(GO:0001836)
Response to cycloheximide
(GO:0046898)
Response to cytokine
(GO:0034097)
Response to ischemia
(GO:0002931)
Response to radiation
(GO:0009314)
Response to virus
(GO:0009615)
Spermatogenesis
(GO:0007283)
Synaptic vesicle recycling via endosome
(GO:0036466)

Other Information

Proteins

Bcl-2-like protein 1
O35843_MOUSE

Genular Protein ID: 479306062

Symbol: B2CL1_MOUSE

Name: Bcl-2-like protein 1

UniProtKB Accession Codes:

Q64373 O35844 Q60657 Q60658 Q61338

Database IDs:

Citations:

PubMed ID: 7607090

Title: bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria.

PubMed ID: 7607090

DOI: 10.1242/dev.120.10.3033

PubMed ID: 7963517

Title: Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes.

PubMed ID: 7963517

PubMed ID: 9390687

Title: A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells.

PubMed ID: 9390687

DOI: 10.1016/s1074-7613(00)80384-2

PubMed ID: 9144489

Title: Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene.

PubMed ID: 9144489

PubMed ID: 16509771

Title: IAN family critically regulates survival and development of T lymphocytes.

PubMed ID: 16509771

DOI: 10.1371/journal.pbio.0040103

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21502331

Title: Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells.

PubMed ID: 21502331

DOI: 10.1084/jem.20101192

PubMed ID: 27013495

Title: The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis.

PubMed ID: 27013495

DOI: 10.15252/embr.201541392

PubMed ID: 14499110

Title: The structure of a Bcl-xL/Bim fragment complex: implications for Bim function.

PubMed ID: 14499110

DOI: 10.1016/s1074-7613(03)00234-6

Sequence Information:

Length: 233
Mass: 26132
Checksum: 24D2AC79887E072E
Sequence:

MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEE TEAERETPSA INGNPSWHLA 
DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDEFELR YRRAFSDLTS QLHITPGTAY 
QSFEQVVNEL FRDGVNWGRI VAFFSFGGAL CVESVDKEMQ VLVSRIASWM ATYLNDHLEP 
WIQENGGWDT FVDLYGNNAA AESRKGQERF NRWFLTGMTV AGVVLLGSLF SRK

Genular Protein ID: 83203069

Symbol: O35843_MOUSE

Name: N/A

UniProtKB Accession Codes:

O35843

Database IDs:

Citations:

PubMed ID: 9390687

Title: A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells.

PubMed ID: 9390687

DOI: 10.1016/S1074-7613(00)80384-2

Sequence Information:

Length: 235
Mass: 26122
Checksum: 649D914C2D5378F6
Sequence:

MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEE TEAERETPSA INGNPSWHLA 
DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDEFELR YRRAFSDLTS QLHITPGTAY 
QSFEQVVNEL FRDGVNWGRI VAFFSFGGAL CVESVDKEMQ VLVSRIASWM ATYLNDHLEP 
WIQENGGWGV SGGTPLRSVF RRLVQVPGVA EHVCDPSLWE VETEGSEVQG PPQLL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bcl2l1

Associated with

Other Information

bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. PubMed ID: 7607090

Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes. PubMed ID: 7963517

A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells. PubMed ID: 9390687

Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene. PubMed ID: 9144489

IAN family critically regulates survival and development of T lymphocytes. PubMed ID: 16509771

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells. PubMed ID: 21502331

The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis. PubMed ID: 27013495

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. PubMed ID: 14499110

A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells. PubMed ID: 9390687

Database document:

PubMed ID: 7607090

PubMed ID: 7963517

PubMed ID: 9390687

PubMed ID: 9144489

PubMed ID: 16509771

PubMed ID: 21183079

PubMed ID: 21502331

PubMed ID: 27013495

PubMed ID: 14499110

PubMed ID: 9390687