Genular: Defining Cellular Identity and Function

Details for: Bcl2l10

Gene ID: 12049

Symbol: Bcl2l10

Ensembl ID: ENSMUSG00000032191

Description: Bcl2-like 10

Associated with

Apoptotic process
(GO:0006915)
Calcium ion binding
(GO:0005509)
Caspase binding
(GO:0089720)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Extrinsic apoptotic signaling pathway in absence of ligand
(GO:0097192)
Extrinsic apoptotic signaling pathway via death domain receptors
(GO:0008625)
Identical protein binding
(GO:0042802)
Intrinsic apoptotic signaling pathway
(GO:0097193)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Membrane
(GO:0016020)
Microtubule organizing center organization
(GO:0031023)
Mitochondria-associated endoplasmic reticulum membrane
(GO:0044233)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
(GO:2001240)
Negative regulation of intrinsic apoptotic signaling pathway
(GO:2001243)
Nucleus
(GO:0005634)
Positive regulation of apoptotic process
(GO:0043065)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of apoptotic process
(GO:0042981)
Spindle
(GO:0005819)

Other Information

Proteins

B2L10_MOUSE

Genular Protein ID: 1898085820

Symbol: B2L10_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9Z0F3 Q3ULP5 Q7TPY8

Database IDs:

Citations:

PubMed ID: 9878060

Title: Boo, a novel negative regulator of cell death, interacts with Apaf-1.

PubMed ID: 9878060

DOI: 10.1093/emboj/18.1.167

PubMed ID: 9829980

Title: Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death.

PubMed ID: 9829980

DOI: 10.1074/jbc.273.49.32479

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17532299

Title: NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling.

PubMed ID: 17532299

DOI: 10.1016/j.bbrc.2007.05.090

PubMed ID: 27753540

Title: Bcl2l10, a new Tpx2 binding partner, is a master regulator of Aurora kinase A in mouse oocytes.

PubMed ID: 27753540

DOI: 10.1080/15384101.2016.1243630

PubMed ID: 20455273

Title: The structure of Boo/Diva reveals a divergent Bcl-2 protein.

PubMed ID: 20455273

DOI: 10.1002/prot.22728

Sequence Information:

Length: 191
Mass: 22302
Checksum: 819014E6B2DFE411
Sequence:

MADSQDPLHE RTRRLLSDYI FFCAREPDTP EPPPTSVEAA LLRSVTRQIQ QEHQEFFSSF 
CESRGNRLEL VKQMADKLLS KDQDFSWSQL VMLLAFAGTL MNQGPYMAVK QKRDLGNRVI 
VTRDCCLIVN FLYNLLMGRR HRARLEALGG WDGFCRFFKN PLPLGFWRRL LIQAFLSGFF 
ATAIFFIWKR L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bcl2l10

Associated with

Other Information

Boo, a novel negative regulator of cell death, interacts with Apaf-1. PubMed ID: 9878060

Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death. PubMed ID: 9829980

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

NM23-H2 involves in negative regulation of Diva and Bcl2L10 in apoptosis signaling. PubMed ID: 17532299

Bcl2l10, a new Tpx2 binding partner, is a master regulator of Aurora kinase A in mouse oocytes. PubMed ID: 27753540

The structure of Boo/Diva reveals a divergent Bcl-2 protein. PubMed ID: 20455273