Bcl2l2 | ENSMUSG00000089682 | NCBI 12050

Details for: Bcl2l2

Gene ID: 12050

Symbol: Bcl2l2

Ensembl ID: ENSMUSG00000089682

Description: BCL2-like 2

Associated with

Apoptotic process
(GO:0006915)
Bcl-2 family protein complex
(GO:0097136)
Bh domain binding
(GO:0051400)
Cytosol
(GO:0005829)
Disordered domain specific binding
(GO:0097718)
Extrinsic apoptotic signaling pathway in absence of ligand
(GO:0097192)
Identical protein binding
(GO:0042802)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Membrane
(GO:0016020)
Mitochondrial membrane
(GO:0031966)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Negative regulation of intrinsic apoptotic signaling pathway
(GO:2001243)
Negative regulation of mitochondrial membrane permeability
(GO:0035795)
Negative regulation of release of cytochrome c from mitochondria
(GO:0090201)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of apoptotic process
(GO:0042981)
Sertoli cell proliferation
(GO:0060011)

Other Information

Proteins

Bcl-2-like protein 2

Genular Protein ID: 1629692186

Symbol: B2CL2_MOUSE

Name: Bcl-2-like protein 2

UniProtKB Accession Codes:

P70345 Q545Q4 Q6A093 Q8CFR2 Q8CGL4 Q9CYW5

Database IDs:

Citations:

PubMed ID: 8761287

Title: Bcl-w, a novel member of the Bcl-2 family, promotes cell survival.

PubMed ID: 8761287

PubMed ID: 9500547

Title: Testicular degeneration in Bclw-deficient mice.

PubMed ID: 9500547

DOI: 10.1038/ng0398-251

PubMed ID: 14746907

Title: Mouse keratinocytes express c98, a novel gene homologous to bcl-2, that is stimulated by insulin-like growth factor 1 and prevents dexamethasone-induced apoptosis.

PubMed ID: 14746907

DOI: 10.1016/j.bbaexp.2003.11.006

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15368895

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 15368895

DOI: 10.1093/dnares/11.3.205

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11784036

Title: BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.

PubMed ID: 11784036

DOI: 10.1006/dbio.2001.0445

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21546903

Title: Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins.

PubMed ID: 21546903

DOI: 10.1038/cdd.2011.47

Sequence Information:

Length: 193
Mass: 20790
Checksum: 36CA185F5945DFB4
Sequence:

MATPASTPDT RALVADFVGY KLRQKGYVCG AGPGEGPAAD PLHQAMRAAG DEFETRFRRT 
FSDLAAQLHV TPGSAQQRFT QVSDELFQGG PNWGRLVAFF VFGAALCAES VNKEMEPLVG 
QVQDWMVAYL ETRLADWIHS SGGWAEFTAL YGDGALEEAR RLREGNWASV RTVLTGAVAL 
GALVTVGAFF ASK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bcl2l2

Associated with

Other Information

Bcl-w, a novel member of the Bcl-2 family, promotes cell survival. PubMed ID: 8761287

Testicular degeneration in Bclw-deficient mice. PubMed ID: 9500547

Mouse keratinocytes express c98, a novel gene homologous to bcl-2, that is stimulated by insulin-like growth factor 1 and prevents dexamethasone-induced apoptosis. PubMed ID: 14746907

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. PubMed ID: 15368895

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity. PubMed ID: 11784036

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins. PubMed ID: 21546903