Genular: Defining Cellular Identity and Function

Details for: Bdkrb2

Gene ID: 12062

Symbol: Bdkrb2

Ensembl ID: ENSMUSG00000021070

Description: bradykinin receptor, beta 2

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Acute inflammatory response to antigenic stimulus
(GO:0002438)
Arachidonic acid secretion
(GO:0050482)
Beta-2 adrenergic receptor binding
(GO:0031698)
Bradykinin receptor activity
(GO:0004947)
Endosome
(GO:0005768)
Golgi apparatus
(GO:0005794)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Intracellular membrane-bounded organelle
(GO:0043231)
Intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
(GO:1990127)
Maintenance of blood-brain barrier
(GO:0035633)
Membrane
(GO:0016020)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
(GO:1902219)
Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
(GO:1902239)
Negative regulation of peptidyl-serine phosphorylation
(GO:0033137)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Protease binding
(GO:0002020)
Protein heterodimerization activity
(GO:0046982)
Response to salt stress
(GO:0009651)
Signal transduction
(GO:0007165)
Smooth muscle contraction
(GO:0006939)
Type 1 angiotensin receptor binding
(GO:0031702)
Vasoconstriction
(GO:0042310)
Vasodilation
(GO:0042311)

Other Information

Proteins

B2 bradykinin receptor

Genular Protein ID: 4294306623

Symbol: BKRB2_MOUSE

Name: B2 bradykinin receptor

UniProtKB Accession Codes:

P32299 B9EHE3

Database IDs:

Citations:

PubMed ID: 8394991

Title: Cloned murine bradykinin receptor exhibits a mixed B1 and B2 pharmacological selectivity.

PubMed ID: 8394991

PubMed ID: 8302267

Title: Differential pharmacology of cloned human and mouse B2 bradykinin receptors.

PubMed ID: 8302267

PubMed ID: 8166739

Title: B2 bradykinin receptors in NG108-15 cells: cDNA cloning and functional expression.

PubMed ID: 8166739

DOI: 10.1006/bbrc.1994.1495

PubMed ID: 7959003

Title: Cloning, sequence analysis and expression of the gene encoding the mouse bradykinin B2 receptor.

PubMed ID: 7959003

DOI: 10.1016/0378-1119(94)90162-7

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8652530

Title: Structure of the bradykinin B2 receptors' amino terminus.

PubMed ID: 8652530

DOI: 10.1021/bi9601060

Sequence Information:

Length: 392
Mass: 44389
Checksum: FB1AA59BCBFFF5F9
Sequence:

MPCSWKLLGF LSVHEPMPTA ASFGIEMFNV TTQVLGSALN GTLSKDNCPD TEWWSWLNAI 
QAPFLWVLFL LAALENLFVL SVFFLHKNSC TVAEIYLGNL AAADLILACG LPFWAITIAN 
NFDWVFGEVL CRVVNTMIYM NLYSSICFLM LVSIDRYLAL VKTMSMGRMR GVRWAKLYSL 
VIWGCTLLLS SPMLVFRTMR EYSEEGHNVT ACVIVYPSRS WEVFTNVLLN LVGFLLPLSV 
ITFCTVRILQ VLRNNEMKKF KEVQTERKAT VLVLAVLGLF VLCWVPFQIS TFLDTLLRLG 
VLSGCWDEHA VDVITQISSY VAYSNSGLNP LVYVIVGKRF RKKSREVYRV LCQKGGCMGE 
PVQMENSMGT LRTSISVERQ IHKLQDWAGK KQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bdkrb2

Associated with

Other Information

Cloned murine bradykinin receptor exhibits a mixed B1 and B2 pharmacological selectivity. PubMed ID: 8394991

Differential pharmacology of cloned human and mouse B2 bradykinin receptors. PubMed ID: 8302267

B2 bradykinin receptors in NG108-15 cells: cDNA cloning and functional expression. PubMed ID: 8166739

Cloning, sequence analysis and expression of the gene encoding the mouse bradykinin B2 receptor. PubMed ID: 7959003

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334