Details for: CLNS1A

Gene ID: 1207

Symbol: CLNS1A

Ensembl ID: ENSG00000074201

Description: chloride nucleotide-sensitive channel 1A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 345.8962
    Cell Significance Index: -53.8000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 151.3056
    Cell Significance Index: -62.3300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 140.2178
    Cell Significance Index: -66.2000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 139.0745
    Cell Significance Index: -56.5000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 137.2005
    Cell Significance Index: -34.8000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 122.0389
    Cell Significance Index: -62.7800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 98.7598
    Cell Significance Index: -66.2700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 49.9247
    Cell Significance Index: -61.5600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.5415
    Cell Significance Index: -49.6700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 18.1022
    Cell Significance Index: -55.6000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.2846
    Cell Significance Index: -64.2600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.5371
    Cell Significance Index: -25.2500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.7039
    Cell Significance Index: 162.3300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.5192
    Cell Significance Index: 87.5400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.2533
    Cell Significance Index: 59.2500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.8397
    Cell Significance Index: 20.0000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.5847
    Cell Significance Index: 20.3000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.5761
    Cell Significance Index: 216.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.5118
    Cell Significance Index: 272.5300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.4810
    Cell Significance Index: 31.0000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4739
    Cell Significance Index: 292.5100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.4585
    Cell Significance Index: 179.3300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.4084
    Cell Significance Index: 769.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1411
    Cell Significance Index: 409.3100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.0408
    Cell Significance Index: 8.3100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.0090
    Cell Significance Index: 56.6200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.0040
    Cell Significance Index: 71.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9992
    Cell Significance Index: 200.4300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9569
    Cell Significance Index: 49.7100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9559
    Cell Significance Index: 422.6100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8792
    Cell Significance Index: 41.3200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8501
    Cell Significance Index: 23.1400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.8164
    Cell Significance Index: 60.8500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7906
    Cell Significance Index: 51.0100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.7504
    Cell Significance Index: 88.4900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7303
    Cell Significance Index: 93.6200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.6849
    Cell Significance Index: 88.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6421
    Cell Significance Index: 33.7200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5872
    Cell Significance Index: 40.6100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5049
    Cell Significance Index: 14.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4657
    Cell Significance Index: 420.5200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4290
    Cell Significance Index: 20.0000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3942
    Cell Significance Index: 11.5800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3868
    Cell Significance Index: 66.0400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3370
    Cell Significance Index: 7.3000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2852
    Cell Significance Index: 17.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2682
    Cell Significance Index: 26.5300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2119
    Cell Significance Index: 13.3600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1927
    Cell Significance Index: 133.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1479
    Cell Significance Index: 278.5600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1415
    Cell Significance Index: 217.8000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1329
    Cell Significance Index: 5.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1286
    Cell Significance Index: 3.4400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0842
    Cell Significance Index: 3.1900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0748
    Cell Significance Index: 101.7000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0735
    Cell Significance Index: 135.5900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0587
    Cell Significance Index: 2.6600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0335
    Cell Significance Index: 0.5600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0281
    Cell Significance Index: 17.8500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0251
    Cell Significance Index: 0.6700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0167
    Cell Significance Index: 3.1800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0138
    Cell Significance Index: 0.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0131
    Cell Significance Index: 0.4600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0189
    Cell Significance Index: -14.3400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0215
    Cell Significance Index: -15.9500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0251
    Cell Significance Index: -0.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0260
    Cell Significance Index: -11.8200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0371
    Cell Significance Index: -27.1900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0435
    Cell Significance Index: -7.0700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0445
    Cell Significance Index: -4.5500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0461
    Cell Significance Index: -28.7800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0555
    Cell Significance Index: -8.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0714
    Cell Significance Index: -40.2800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0966
    Cell Significance Index: -7.4100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1010
    Cell Significance Index: -2.9100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1805
    Cell Significance Index: -4.1700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1813
    Cell Significance Index: -38.2000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1847
    Cell Significance Index: -53.1400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2188
    Cell Significance Index: -5.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2200
    Cell Significance Index: -25.2100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3043
    Cell Significance Index: -35.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4788
    Cell Significance Index: -15.3400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5065
    Cell Significance Index: -12.6600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5310
    Cell Significance Index: -55.2900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5911
    Cell Significance Index: -67.4700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.6103
    Cell Significance Index: -5.6200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6479
    Cell Significance Index: -51.3100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6567
    Cell Significance Index: -8.9600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.6801
    Cell Significance Index: -10.1900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.8068
    Cell Significance Index: -19.3500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8903
    Cell Significance Index: -18.9600
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.8966
    Cell Significance Index: -5.6300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.9248
    Cell Significance Index: -27.2400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.9445
    Cell Significance Index: -49.2000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.9476
    Cell Significance Index: -17.5200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.9646
    Cell Significance Index: -27.6500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.0507
    Cell Significance Index: -28.1100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.0597
    Cell Significance Index: -10.9700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0641
    Cell Significance Index: -65.2400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.1049
    Cell Significance Index: -31.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Nucleotide-binding sensitivity:** The CLNS1A channel is activated by nucleotide binding, which triggers chloride ion transport across the plasma membrane. 2. **Cell-type specificity:** CLNS1A is expressed in various cell types, including pro-T cells, mesodermal cells, and epithelial cells of the nephron. 3. **Chloride ion transport:** The channel regulates chloride ion transport, which is essential for maintaining cellular homeostasis and volume. 4. **Cytoskeletal dynamics:** CLNS1A modulates cytoskeletal dynamics, which is crucial for cell migration, differentiation, and survival. **Pathways and Functions:** 1. **Cell volume homeostasis:** CLNS1A regulates chloride ion transport, which helps maintain cellular volume and prevent swelling or shrinkage. 2. **Chloride transport:** The channel plays a critical role in chloride ion transport across the plasma membrane, influencing cellular homeostasis and signaling pathways. 3. **Cytoskeleton regulation:** CLNS1A modulates cytoskeletal dynamics, which is essential for cell migration, differentiation, and survival. 4. **RNA splicing and processing:** The channel is involved in positive regulation of mRNA splicing via the spliceosome, highlighting its role in RNA processing and gene expression. **Clinical Significance:** 1. **Developmental disorders:** CLNS1A mutations have been associated with developmental disorders, such as neural crest cell abnormalities and congenital anomalies. 2. **Cancer:** The channel's role in cell migration and differentiation makes it a potential target for cancer therapy. 3. **Neurological disorders:** CLNS1A mutations have been linked to neurological disorders, such as epilepsy and ataxia. 4. **Renal disease:** The channel's expression in epithelial cells of the nephron makes it a potential target for renal disease therapy. In conclusion, the CLNS1A gene is a complex and multifunctional gene that plays a critical role in cellular homeostasis, development, and disease pathogenesis. Further research is needed to fully elucidate the mechanisms by which CLNS1A regulates cellular processes and to explore its therapeutic potential in various diseases.

Genular Protein ID: 2627404289

Symbol: ICLN_HUMAN

Name: Methylosome subunit pICln

UniProtKB Accession Codes:

P54105 B2RCS9 Q0VDK6 Q9NRD2 Q9NRD3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 2 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SMR 1 STRING 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8579598

Title: The ubiquitously expressed pICln protein forms homomeric complexes in vitro.

PubMed ID: 8579598

DOI: 10.1006/bbrc.1996.0146

PubMed ID: 7887970

Title: Molecular cloning of the human volume-sensitive chloride conductance regulatory protein, pICln, from ocular ciliary epithelium.

PubMed ID: 7887970

DOI: 10.1006/bbrc.1995.1309

PubMed ID: 9359436

Title: Molecular cloning and expression of a chloride channel-associated protein pI(Cln) in human young red blood cells: association with actin.

PubMed ID: 9359436

DOI: 10.1042/bj3270609

PubMed ID: 10825435

Title: Modulation of volume regulated anion current by I(Cln).

PubMed ID: 10825435

DOI: 10.1016/s0005-2736(00)00177-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10330151

Title: pICln inhibits snRNP biogenesis by binding core spliceosomal proteins.

PubMed ID: 10330151

DOI: 10.1128/mcb.19.6.4113

PubMed ID: 11747828

Title: Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln.

PubMed ID: 11747828

DOI: 10.1016/s0960-9822(01)00592-9

PubMed ID: 11713266

Title: The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins.

PubMed ID: 11713266

DOI: 10.1128/mcb.21.24.8289-8300.2001

PubMed ID: 16087681

Title: Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.

PubMed ID: 16087681

DOI: 10.1074/jbc.m505077200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18984161

Title: An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.

PubMed ID: 18984161

DOI: 10.1016/j.cell.2008.09.020

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21081503

Title: RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

PubMed ID: 21081503

DOI: 10.1074/jbc.m110.148486

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 237
  • Mass: 26215
  • Checksum: AE9C09884A6FF158
  • Sequence:
    • MSFLKSFPPP GPAEGLLRQQ PDTEAVLNGK GLGTGTLYIA ESRLSWLDGS GLGFSLEYPT 
ISLHALSRDR SDCLGEHLYV MVNAKFEEES KEPVADEEEE DSDDDVEPIT EFRFVPSDKS 
ALEAMFTAMC ECQALHPDPE DEDSDDYDGE EYDVEAHEQG QGDIPTFYTY EEGLSHLTAE 
GQATLERLEG MLSQSVSSQY NMAGVRTEDS IRDYEDGMEV DTTPTVAGQF EDADVDH

Genular Protein ID: 3748960313

Symbol: E9PJF4_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PJF4

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 179
  • Mass: 19743
  • Checksum: F025C0B5645CBFE1
  • Sequence:
    • MSFLKSFPPP GPAEGLLRQQ PDTEAVLNGK GLGTGTLYIA ESRLSWLDGS GLGFSLEYPT 
ISLHALSRDR SDCLGEHLYV MVNAKFEEES KEPVADEEEE DSDDDVEPIT EFRFVPSDKS 
ALEAMFTAMC ECQALHPDPE DEDSDDYDGE EYDVEAHDGM EVDTTPTVAG QFEDADVDH

Genular Protein ID: 2186699761

Symbol: E9PMI6_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PMI6

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 HGNC 1 IntAct 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 167
  • Mass: 18259
  • Checksum: 5C7241CA193A0D6D
  • Sequence:
    • MSFLKSFPPP GPAEGLLRQQ PDTEAVLNGK GLGTGTLYIA ESRLSWLDGS GLGFSLEYPT 
ISLHALSRDR SDCLGEHLYV MVNAKFEEQG QGDIPTFYTY EEGLSHLTAE GQATLERLEG 
MLSQSVSSQY NMAGVRTEDS IRDYEDGMEV DTTPTVAGQF EDADVDH

Genular Protein ID: 2671242236

Symbol: J3KN38_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KN38

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 203
  • Mass: 22348
  • Checksum: 4B2130D4EEFE1BF8
  • Sequence:
    • MSFLKSFPPP GPAEGLLRQQ PDTEAVLNGK GLGTGTLYIA ESRLSWLDGS GLGFSLEYPT 
ISLHALSRDR SDCLGEHLYV MVNAKFEVEA MFTAMCECQA LHPDPEDEDS DDYDGEEYDV 
EAHEQGQGDI PTFYTYEEGL SHLTAEGQAT LERLEGMLSQ SVSSQYNMAG VRTEDSIRDY 
EDGMEVDTTP TVAGQFEDAD VDH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.