Details for: CLTC

Gene ID: 1213

Symbol: CLTC

Ensembl ID: ENSG00000141367

Description: clathrin heavy chain

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.46
    Marker Score: 43607.5
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.42
    Marker Score: 6495
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 2.41
    Marker Score: 2908.5
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.3
    Marker Score: 2440
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.2
    Marker Score: 5547
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.17
    Marker Score: 7719
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.1
    Marker Score: 4611.5
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.07
    Marker Score: 2179
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.06
    Marker Score: 2357
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.06
    Marker Score: 9516
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.05
    Marker Score: 18033
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.05
    Marker Score: 1953
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.04
    Marker Score: 2348
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.02
    Marker Score: 76846
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 1.99
    Marker Score: 550
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.98
    Marker Score: 73135
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.97
    Marker Score: 1083
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.96
    Marker Score: 1311
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.96
    Marker Score: 3250
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.95
    Marker Score: 38863
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.95
    Marker Score: 16952
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.93
    Marker Score: 19965.5
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.93
    Marker Score: 66728
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.92
    Marker Score: 28664
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.91
    Marker Score: 14678
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.91
    Marker Score: 2037
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.89
    Marker Score: 7930.5
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.88
    Marker Score: 1885
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.87
    Marker Score: 115236
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.87
    Marker Score: 17583
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.86
    Marker Score: 7715
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.86
    Marker Score: 7181
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.84
    Marker Score: 4191.5
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.84
    Marker Score: 3535.5
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.84
    Marker Score: 6313
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.83
    Marker Score: 1044
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.83
    Marker Score: 1091
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.82
    Marker Score: 2581
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.82
    Marker Score: 2679
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.82
    Marker Score: 38782
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.81
    Marker Score: 859
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.81
    Marker Score: 1951
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.81
    Marker Score: 528
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.8
    Marker Score: 11458
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.79
    Marker Score: 834
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.78
    Marker Score: 7239
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.77
    Marker Score: 715
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 1.76
    Marker Score: 3213
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.74
    Marker Score: 16518.5
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.74
    Marker Score: 1084.5
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.72
    Marker Score: 5405
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.72
    Marker Score: 2217
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.72
    Marker Score: 57979
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.71
    Marker Score: 6330
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.71
    Marker Score: 14675
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.71
    Marker Score: 715
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.71
    Marker Score: 414
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.71
    Marker Score: 1161.5
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.7
    Marker Score: 1471
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.7
    Marker Score: 6682.5
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.69
    Marker Score: 8867
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.69
    Marker Score: 12543
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.68
    Marker Score: 1860
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.68
    Marker Score: 980
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.68
    Marker Score: 1705
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.67
    Marker Score: 974
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.67
    Marker Score: 1111
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.67
    Marker Score: 616
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.66
    Marker Score: 26715
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.66
    Marker Score: 868.5
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.66
    Marker Score: 2004
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.66
    Marker Score: 3964
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.65
    Marker Score: 814
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.64
    Marker Score: 1927
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.64
    Marker Score: 1154
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.64
    Marker Score: 794
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.63
    Marker Score: 10620
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.63
    Marker Score: 41710
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.63
    Marker Score: 91050
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 1.62
    Marker Score: 3087
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.62
    Marker Score: 7772
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.62
    Marker Score: 386
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.62
    Marker Score: 803
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.61
    Marker Score: 1740
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.61
    Marker Score: 1726.5
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.61
    Marker Score: 1100
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.61
    Marker Score: 9556
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.6
    Marker Score: 2579
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.6
    Marker Score: 463
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.6
    Marker Score: 1084
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 1.6
    Marker Score: 595
  • Cell Name: club cell (CL0000158)
    Fold Change: 1.6
    Marker Score: 1863
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.6
    Marker Score: 8368.5
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: 1.59
    Marker Score: 417
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.58
    Marker Score: 3945
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.58
    Marker Score: 1448.5
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.57
    Marker Score: 15828
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.57
    Marker Score: 35127
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 1.57
    Marker Score: 1116
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.57
    Marker Score: 2856

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Other Information

**Key characteristics:** * The CLH1 gene is located on chromosome 17. * It is a member of the immunoglobulin superfamily, which are involved in cell adhesion, membrane trafficking, and signaling. * CLH1 is a glycoprotein with a molecular weight of approximately 120 kDa. * It is a transmembrane protein with a cytoplasmic tail that is responsible for its interaction with other proteins. **Pathways and functions:** * CLH1 is involved in the assembly and trafficking of membrane vesicles in epithelial and myeloid cells. * It is a key regulator of epithelial cell migration and cell adhesion. * It is also involved in the regulation of immune cell function. * CLH1 has been shown to be involved in the development and maintenance of the kidney. * It is also involved in the assembly and trafficking of plasma lipoprotein particles. **Clinical significance:** * Mutations in the CLTC gene have been linked to several human diseases, including kidney disease, cancer, and autoimmune disorders. * CLH1 is a potential therapeutic target for these diseases. **Additional notes:** * CLH1 is a highly conserved protein, with similar genes found in other species. * It is expressed in a variety of cell types, including epithelial cells, endothelial cells, and immune cells. * CLH1 is a key regulator of cell migration, adhesion, and signaling.

Genular Protein ID: 3451335350

Symbol: CLH1_HUMAN

Name: Clathrin heavy chain on chromosome 17

UniProtKB Accession Codes:

Q00610 D3DU00 Q6N0A0 Q86TF2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 7 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 45 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 MoonDB 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 8 PIR 1 PIRSF 1 PRIDE 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 20 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7584026

Title: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

PubMed ID: 7584026

DOI: 10.1093/dnares/1.1.27

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1765375

Title: Human clathrin heavy chain (CLTC): partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter.

PubMed ID: 1765375

DOI: 10.1016/0888-7543(91)90115-u

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 11532990

Title: The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis.

PubMed ID: 11532990

DOI: 10.1093/hmg/10.17.1807

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 16314522

Title: Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.

PubMed ID: 16314522

DOI: 10.1128/mcb.25.24.11005-11018.2005

PubMed ID: 15858577

Title: Clathrin is required for the function of the mitotic spindle.

PubMed ID: 15858577

DOI: 10.1038/nature03502

PubMed ID: 16968737

Title: Trimerisation is important for the function of clathrin at the mitotic spindle.

PubMed ID: 16968737

DOI: 10.1242/jcs.03192

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 18529014

Title: FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes.

PubMed ID: 18529014

DOI: 10.1021/bi8001506

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20639872

Title: Plasma membrane contributes to the formation of pre-autophagosomal structures.

PubMed ID: 20639872

DOI: 10.1038/ncb2078

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21297582

Title: A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.

PubMed ID: 21297582

DOI: 10.1038/emboj.2011.15

PubMed ID: 21266579

Title: Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.

PubMed ID: 21266579

DOI: 10.1074/jbc.m110.185793

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23918938

Title: Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding.

PubMed ID: 23918938

DOI: 10.1083/jcb.201211127

PubMed ID: 23532825

Title: Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension.

PubMed ID: 23532825

DOI: 10.1242/jcs.124834

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25066864

Title: Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B.

PubMed ID: 25066864

DOI: 10.1016/j.mcn.2014.07.006

PubMed ID: 25596274

Title: TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation.

PubMed ID: 25596274

DOI: 10.1242/bio.201410843

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27022195

Title: Raftlin controls lipopolysaccharide-induced TLR4 internalization and TICAM-1 signaling in a cell type-specific manner.

PubMed ID: 27022195

DOI: 10.4049/jimmunol.1501734

PubMed ID: 21816279

Title: Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition.

PubMed ID: 21816279

DOI: 10.1016/j.cell.2011.06.025

PubMed ID: 26756164

Title: USP2-45 is a circadian clock output effector regulating calcium absorption at the post-translational level.

PubMed ID: 26756164

DOI: 10.1371/journal.pone.0145155

PubMed ID: 26822784

Title: CLTC as a clinically novel gene associated with multiple malformations and developmental delay.

PubMed ID: 26822784

DOI: 10.1002/ajmg.a.37506

PubMed ID: 29100083

Title: High rate of recurrent de novo mutations in developmental and epileptic encephalopathies.

PubMed ID: 29100083

DOI: 10.1016/j.ajhg.2017.09.008

Sequence Information:

  • Length: 1675
  • Mass: 191615
  • Checksum: 6C4F2D54950079E2
  • Sequence:
    • MAQILPIRFQ EHLQLQNLGI NPANIGFSTL TMESDKFICI REKVGEQAQV VIIDMNDPSN 
PIRRPISADS AIMNPASKVI ALKAGKTLQI FNIEMKSKMK AHTMTDDVTF WKWISLNTVA 
LVTDNAVYHW SMEGESQPVK MFDRHSSLAG CQIINYRTDA KQKWLLLTGI SAQQNRVVGA 
MQLYSVDRKV SQPIEGHAAS FAQFKMEGNA EESTLFCFAV RGQAGGKLHI IEVGTPPTGN 
QPFPKKAVDV FFPPEAQNDF PVAMQISEKH DVVFLITKYG YIHLYDLETG TCIYMNRISG 
ETIFVTAPHE ATAGIIGVNR KGQVLSVCVE EENIIPYITN VLQNPDLALR MAVRNNLAGA 
EELFARKFNA LFAQGNYSEA AKVAANAPKG ILRTPDTIRR FQSVPAQPGQ TSPLLQYFGI 
LLDQGQLNKY ESLELCRPVL QQGRKQLLEK WLKEDKLECS EELGDLVKSV DPTLALSVYL 
RANVPNKVIQ CFAETGQVQK IVLYAKKVGY TPDWIFLLRN VMRISPDQGQ QFAQMLVQDE 
EPLADITQIV DVFMEYNLIQ QCTAFLLDAL KNNRPSEGPL QTRLLEMNLM HAPQVADAIL 
GNQMFTHYDR AHIAQLCEKA GLLQRALEHF TDLYDIKRAV VHTHLLNPEW LVNYFGSLSV 
EDSLECLRAM LSANIRQNLQ ICVQVASKYH EQLSTQSLIE LFESFKSFEG LFYFLGSIVN 
FSQDPDVHFK YIQAACKTGQ IKEVERICRE SNCYDPERVK NFLKEAKLTD QLPLIIVCDR 
FDFVHDLVLY LYRNNLQKYI EIYVQKVNPS RLPVVIGGLL DVDCSEDVIK NLILVVRGQF 
STDELVAEVE KRNRLKLLLP WLEARIHEGC EEPATHNALA KIYIDSNNNP ERFLRENPYY 
DSRVVGKYCE KRDPHLACVA YERGQCDLEL INVCNENSLF KSLSRYLVRR KDPELWGSVL 
LESNPYRRPL IDQVVQTALS ETQDPEEVSV TVKAFMTADL PNELIELLEK IVLDNSVFSE 
HRNLQNLLIL TAIKADRTRV MEYINRLDNY DAPDIANIAI SNELFEEAFA IFRKFDVNTS 
AVQVLIEHIG NLDRAYEFAE RCNEPAVWSQ LAKAQLQKGM VKEAIDSYIK ADDPSSYMEV 
VQAANTSGNW EELVKYLQMA RKKARESYVE TELIFALAKT NRLAELEEFI NGPNNAHIQQ 
VGDRCYDEKM YDAAKLLYNN VSNFGRLAST LVHLGEYQAA VDGARKANST RTWKEVCFAC 
VDGKEFRLAQ MCGLHIVVHA DELEELINYY QDRGYFEELI TMLEAALGLE RAHMGMFTEL 
AILYSKFKPQ KMREHLELFW SRVNIPKVLR AAEQAHLWAE LVFLYDKYEE YDNAIITMMN 
HPTDAWKEGQ FKDIITKVAN VELYYRAIQF YLEFKPLLLN DLLMVLSPRL DHTRAVNYFS 
KVKQLPLVKP YLRSVQNHNN KSVNESLNNL FITEEDYQAL RTSIDAYDNF DNISLAQRLE 
KHELIEFRRI AAYLFKGNNR WKQSVELCKK DSLYKDAMQY ASESKDTELA EELLQWFLQE 
EKRECFGACL FTCYDLLRPD VVLETAWRHN IMDFAMPYFI QVMKEYLTKV DKLDASESLR 
KEEEQATETQ PIVYGQPQLM LTAGPSVAVP PQAPFGYGYT APPYGQPQPG FGYSM

Genular Protein ID: 2424466130

Symbol: A0A087WVQ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WVQ6 J3KSQ2

Database IDs:

ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 EMBL 3 EPD 1 Ensembl 2 GO 10 Gene3D 3 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PROSITE 1 PROSITE-ProRule 1 Pfam 5 Proteomes 2 RefSeq 1 SMART 1 SUPFAM 2 UCSC 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 1679
  • Mass: 192058
  • Checksum: 9E4E36D1E25FB0DA
  • Sequence:
    • MAQILPIRFQ EHLQLQNLGI NPANIGFSTL TMESDKFICI REKVGEQAQV VIIDMNDPSN 
PIRRPISADS AIMNPASKVI ALKGIKESGK TLQIFNIEMK SKMKAHTMTD DVTFWKWISL 
NTVALVTDNA VYHWSMEGES QPVKMFDRHS SLAGCQIINY RTDAKQKWLL LTGISAQQNR 
VVGAMQLYSV DRKVSQPIEG HAASFAQFKM EGNAEESTLF CFAVRGQAGG KLHIIEVGTP 
PTGNQPFPKK AVDVFFPPEA QNDFPVAMQI SEKHDVVFLI TKYGYIHLYD LETGTCIYMN 
RISGETIFVT APHEATAGII GVNRKGQVLS VCVEEENIIP YITNVLQNPD LALRMAVRNN 
LAGAEELFAR KFNALFAQGN YSEAAKVAAN APKGILRTPD TIRRFQSVPA QPGQTSPLLQ 
YFGILLDQGQ LNKYESLELC RPVLQQGRKQ LLEKWLKEDK LECSEELGDL VKSVDPTLAL 
SVYLRANVPN KVIQCFAETG QVQKIVLYAK KVGYTPDWIF LLRNVMRISP DQGQQFAQML 
VQDEEPLADI TQIVDVFMEY NLIQQCTAFL LDALKNNRPS EGPLQTRLLE MNLMHAPQVA 
DAILGNQMFT HYDRAHIAQL CEKAGLLQRA LEHFTDLYDI KRAVVHTHLL NPEWLVNYFG 
SLSVEDSLEC LRAMLSANIR QNLQICVQVA SKYHEQLSTQ SLIELFESFK SFEGLFYFLG 
SIVNFSQDPD VHFKYIQAAC KTGQIKEVER ICRESNCYDP ERVKNFLKEA KLTDQLPLII 
VCDRFDFVHD LVLYLYRNNL QKYIEIYVQK VNPSRLPVVI GGLLDVDCSE DVIKNLILVV 
RGQFSTDELV AEVEKRNRLK LLLPWLEARI HEGCEEPATH NALAKIYIDS NNNPERFLRE 
NPYYDSRVVG KYCEKRDPHL ACVAYERGQC DLELINVCNE NSLFKSLSRY LVRRKDPELW 
GSVLLESNPY RRPLIDQVVQ TALSETQDPE EVSVTVKAFM TADLPNELIE LLEKIVLDNS 
VFSEHRNLQN LLILTAIKAD RTRVMEYINR LDNYDAPDIA NIAISNELFE EAFAIFRKFD 
VNTSAVQVLI EHIGNLDRAY EFAERCNEPA VWSQLAKAQL QKGMVKEAID SYIKADDPSS 
YMEVVQAANT SGNWEELVKY LQMARKKARE SYVETELIFA LAKTNRLAEL EEFINGPNNA 
HIQQVGDRCY DEKMYDAAKL LYNNVSNFGR LASTLVHLGE YQAAVDGARK ANSTRTWKEV 
CFACVDGKEF RLAQMCGLHI VVHADELEEL INYYQDRGYF EELITMLEAA LGLERAHMGM 
FTELAILYSK FKPQKMREHL ELFWSRVNIP KVLRAAEQAH LWAELVFLYD KYEEYDNAII 
TMMNHPTDAW KEGQFKDIIT KVANVELYYR AIQFYLEFKP LLLNDLLMVL SPRLDHTRAV 
NYFSKVKQLP LVKPYLRSVQ NHNNKSVNES LNNLFITEED YQALRTSIDA YDNFDNISLA 
QRLEKHELIE FRRIAAYLFK GNNRWKQSVE LCKKDSLYKD AMQYASESKD TELAEELLQW 
FLQEEKRECF GACLFTCYDL LRPDVVLETA WRHNIMDFAM PYFIQVMKEY LTKVDKLDAS 
ESLRKEEEQA TETQPIVYGQ PQLMLTAGPS VAVPPQAPFG YGYTAPPYGQ PQPGFGYSM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.