Genular: Defining Cellular Identity and Function

Details for: Prdm1

Gene ID: 12142

Symbol: Prdm1

Ensembl ID: ENSMUSG00000038151

Description: PR domain containing 1, with ZNF domain

Associated with

Adaptive immune response
(GO:0002250)
Aorta development
(GO:0035904)
Artery morphogenesis
(GO:0048844)
Cardiac septum development
(GO:0003279)
Cell fate commitment
(GO:0045165)
Cellular developmental process
(GO:0048869)
Coronary vasculature development
(GO:0060976)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Embryonic placenta development
(GO:0001892)
Eye photoreceptor cell development
(GO:0042462)
Gene expression
(GO:0010467)
Germ cell development
(GO:0007281)
Heart valve development
(GO:0003170)
Histone methyltransferase binding
(GO:1990226)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Intestinal epithelial cell development
(GO:0060576)
In utero embryonic development
(GO:0001701)
Kidney development
(GO:0001822)
Maternal placenta development
(GO:0001893)
Metal ion binding
(GO:0046872)
Methylation
(GO:0032259)
Methyltransferase activity
(GO:0008168)
Morphogenesis of a branching structure
(GO:0001763)
Multicellular organism development
(GO:0007275)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Peptidyl-arginine methylation
(GO:0018216)
Positive regulation of gene expression
(GO:0010628)
Post-embryonic development
(GO:0009791)
Promoter-specific chromatin binding
(GO:1990841)
Protein binding
(GO:0005515)
Regulation of cell population proliferation
(GO:0042127)
Regulation of extrathymic t cell differentiation
(GO:0033082)
Regulation of natural killer cell differentiation
(GO:0032823)
Regulation of nk t cell differentiation
(GO:0051136)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Retinal bipolar neuron differentiation
(GO:0060040)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sebum secreting cell proliferation
(GO:1990654)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription cis-regulatory region binding
(GO:0000976)
Transferase activity
(GO:0016740)
Trophoblast giant cell differentiation
(GO:0060707)
Ventricular septum development
(GO:0003281)

Other Information

Proteins

PR domain zinc finger protein 1

Genular Protein ID: 3231093664

Symbol: PRDM1_MOUSE

Name: PR domain zinc finger protein 1

UniProtKB Accession Codes:

Q60636 A2VDE8 Q3UET9

Database IDs:

Citations:

PubMed ID: 8168136

Title: Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells.

PubMed ID: 8168136

DOI: 10.1016/0092-8674(94)90321-2

PubMed ID: 11121475

Title: Characterization of the B lymphocyte-induced maturation protein-1 (Blimp-1) gene, mRNA isoforms and basal promoter.

PubMed ID: 11121475

DOI: 10.1093/nar/28.24.4846

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16699504

Title: Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

PubMed ID: 16699504

DOI: 10.1038/ncb1413

PubMed ID: 19737919

Title: Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation.

PubMed ID: 19737919

DOI: 10.1128/mcb.00670-09

PubMed ID: 27102484

Title: Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.

PubMed ID: 27102484

DOI: 10.1126/science.aad2035

PubMed ID: 32741026

Title: Early estrogen-induced gene 1 facilitates osteoclast formation through the inhibition of interferon regulatory factor 8 expression.

PubMed ID: 32741026

DOI: 10.1096/fj.202001197r

Sequence Information:

Length: 856
Mass: 95836
Checksum: B9AC6FC2E29ECF4A
Sequence:

MREAYLRCWI FSWKNVWVRP CQRLHFKTVL LQGSLLYTAL DSYSTVQAAP KSSSGSVKFQ 
GLAETGIMKM DMEDADMTLW TEAEFEEKCT YIVNDHPWDS GADGGTSVQA EASLPRNLLF 
KYAANNSKEV IGVVSKEYIP KGTRFGPLIG EVYTNDTVPK NANRKYFWRI YSREEFHHFI 
DGFNEEKSNW MRYVNPAHSA REQNLAACQN GMNIYFYTIK PIPANQELLV WYCRDFAERL 
HYPYPGELTV INLTQTESNP KQYSSEKNEL YPKSVPKREY SVKEILKLDS NPSKRKDIYR 
SNISPFTLEK DMDGFRKNGS PDMPFYPRVV YPIRAPLPED FLKASLAYGM ERPTYITHSP 
LPSSTTPSPP ASSSPEQSLK SSSPHSSPGN TVSPLAPGLP EHRDSYSYLN VSYGSEGLGS 
YPGYAPAPHL PPAFIPSYNA HYPKFLLPPY GISSNGLSTM NNINGINNFS LFPRLYPVYS 
NLLSGSSLPH PMLNPASLPS SLPTDGARRL LPPEHPKEVL IPAPHSAFSL TGAAASMKDE 
SSPPSGSPTA GTAATSEHVV QPKATSSVMA APSTDGAMNL IKNKRNMTGY KTLPYPLKKQ 
NGKIKYECNV CAKTFGQLSN LKVHLRVHSG ERPFKCQTCN KGFTQLAHLQ KHYLVHTGEK 
PHECQVCHKR FSSTSNLKTH LRLHSGEKPY QCKVCPAKFT QFVHLKLHKR LHTRERPHKC 
AQCHKSYIHL CSLKVHLKGN CPAGPAAGLP LEDLTRINEE IERFDISDNA DRLEDMEDSV 
DVTSMVEKEI LAVVRKEKEE TSLKVSLQRN MGNGLLSSGC SLYESSDLSL MKLPHSNPLP 
LVPVKVKQET VEPMDP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prdm1

Associated with

Other Information

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. PubMed ID: 8168136

Characterization of the B lymphocyte-induced maturation protein-1 (Blimp-1) gene, mRNA isoforms and basal promoter. PubMed ID: 11121475

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. PubMed ID: 16699504

Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. PubMed ID: 19737919

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. PubMed ID: 27102484

Early estrogen-induced gene 1 facilitates osteoclast formation through the inhibition of interferon regulatory factor 8 expression. PubMed ID: 32741026