Details for: Blk
Associated with
Other Information
Genular Protein ID: 2654975698
Symbol: BLK_MOUSE
Name: Tyrosine-protein kinase Blk
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2404338
Title: Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells.
PubMed ID: 2404338
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1714601
Title: Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases.
PubMed ID: 1714601
PubMed ID: 1537861
Title: Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk.
PubMed ID: 1537861
PubMed ID: 1506682
Title: The MB-1/B29 heterodimer couples the B cell antigen receptor to multiple src family protein tyrosine kinases.
PubMed ID: 1506682
PubMed ID: 7690139
Title: Antisense oligodeoxynucleotides to the blk tyrosine kinase prevent anti-mu-chain-mediated growth inhibition and apoptosis in a B-cell lymphoma.
PubMed ID: 7690139
PubMed ID: 8195169
Title: Specific recognition of the blk promoter by the B-lymphoid transcription factor B-cell-specific activator protein.
PubMed ID: 8195169
PubMed ID: 7524079
Title: Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement.
PubMed ID: 7524079
PubMed ID: 7608542
Title: Differential expression of the blk and ret tyrosine kinases during B lineage development is dependent on Ig rearrangement.
PubMed ID: 7608542
PubMed ID: 7592958
Title: Reconstitution of the B cell antigen receptor signaling components in COS cells.
PubMed ID: 7592958
PubMed ID: 7565679
Title: Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase.
PubMed ID: 7565679
PubMed ID: 9177269
Title: Palmitylation of Src family tyrosine kinases regulates functional interaction with a B cell substrate.
PubMed ID: 9177269
PubMed ID: 9660839
Title: The transcription factor NF-kappaB/p50 interacts with the blk gene during B cell activation.
PubMed ID: 9660839
PubMed ID: 9636152
Title: Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase.
PubMed ID: 9636152
PubMed ID: 10449731
Title: Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination.
PubMed ID: 10449731
PubMed ID: 14662906
Title: Mimicry of pre-B-cell receptor signaling by activation of the tyrosine kinase Blk.
PubMed ID: 14662906
DOI: 10.1084/jem.20030729
PubMed ID: 12563261
Title: Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development.
PubMed ID: 12563261
DOI: 10.1038/ni893
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 23562159
Title: A network of high-mobility group box transcription factors programs innate interleukin-17 production.
PubMed ID: 23562159
PubMed ID: 8639560
Title: The three-dimensional solution structure of the SH2 domain from p55blk kinase.
PubMed ID: 8639560
DOI: 10.1021/bi960157x
Sequence Information:
- Length: 499
- Mass: 56674
- Checksum: 14C607564BB4E66D
- Sequence:
MGLLSSKRQV SEKGKGWSPV KIRTQDKAPP PLPPLVVFNH LAPPSPNQDP DEEERFVVAL FDYAAVNDRD LQVLKGEKLQ VLRSTGDWWL ARSLVTGREG YVPSNFVAPV ETLEVEKWFF RTISRKDAER QLLAPMNKAG SFLIRESESN KGAFSLSVKD ITTQGEVVKH YKIRSLDNGG YYISPRITFP TLQALVQHYS KKGDGLCQKL TLPCVNLAPK NLWAQDEWEI PRQSLKLVRK LGSGQFGEVW MGYYKNNMKV AIKTLKEGTM SPEAFLGEAN VMKTLQHERL VRLYAVVTRE PIYIVTEYMA RGCLLDFLKT DEGSRLSLPR LIDMSAQVAE GMAYIERMNS IHRDLRAANI LVSETLCCKI ADFGLARIID SEYTAQEGAK FPIKWTAPEA IHFGVFTIKA DVWSFGVLLM EIVTYGRVPY PGMSNPEVIR SLEHGYRMPC PETCPPELYN DIITECWRGR PEERPTFEFL QSVLEDFYTA TEGQYELQP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.