Genular: Defining Cellular Identity and Function

Details for: Bmp1

Gene ID: 12153

Symbol: Bmp1

Ensembl ID: ENSMUSG00000022098

Description: bone morphogenetic protein 1

Associated with

Anchoring fibril formation
(R-MMU-2214320)
Assembly of collagen fibrils and other multimeric structures
(R-MMU-2022090)
Collagen biosynthesis and modifying enzymes
(R-MMU-1650814)
Collagen formation
(R-MMU-1474290)
Crosslinking of collagen fibrils
(R-MMU-2243919)
Extracellular matrix organization
(R-MMU-1474244)
Hdl assembly
(R-MMU-8963896)
Plasma lipoprotein assembly
(R-MMU-8963898)
Plasma lipoprotein assembly, remodeling, and clearance
(R-MMU-174824)
Transport of small molecules
(R-MMU-382551)
Calcium ion binding
(GO:0005509)
Cartilage development
(GO:0051216)
Cell differentiation
(GO:0030154)
Collagen-containing extracellular matrix
(GO:0062023)
Cytokine activity
(GO:0005125)
Dorsal/ventral pattern formation
(GO:0009953)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Growth factor activity
(GO:0008083)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Metalloendopeptidase activity
(GO:0004222)
Metallopeptidase activity
(GO:0008237)
Multicellular organism development
(GO:0007275)
Ossification
(GO:0001503)
Peptidase activity
(GO:0008233)
Positive regulation of cartilage development
(GO:0061036)
Protein binding
(GO:0005515)
Protein processing
(GO:0016485)
Proteolysis
(GO:0006508)
Vesicle
(GO:0031982)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Bone morphogenetic protein 1

Genular Protein ID: 3611018628

Symbol: BMP1_MOUSE

Name: Bone morphogenetic protein 1

UniProtKB Accession Codes:

P98063 Q6NZM2

Database IDs:

Citations:

PubMed ID: 8174772

Title: Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase.

PubMed ID: 8174772

DOI: 10.1006/dbio.1994.1133

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8951074

Title: Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid.

PubMed ID: 8951074

DOI: 10.1242/dev.122.11.3587

PubMed ID: 20181949

Title: Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase.

PubMed ID: 20181949

DOI: 10.1074/jbc.m109.088864

PubMed ID: 24419319

Title: Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.

PubMed ID: 24419319

DOI: 10.1093/hmg/ddu013

PubMed ID: 28068493

Title: BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis.

PubMed ID: 28068493

DOI: 10.1177/0022034516686558

Sequence Information:

Length: 991
Mass: 111666
Checksum: F838441CF1DA9F1A
Sequence:

MPGVARPPLP LLSLPLLLLL LLLPRAGRPL DLADYTYDLG EEDAPELLNY KDPCKAAAFL 
GDIALDEEDL RAFQVQQAAV LRQQTARRPS IKAAGNSSAL GGQGTSGQPQ RESRGRWRGR 
PRSRRAATSR PERVWPDGVI PFVIGGNFTG SQRAVFRQAM RHWEKHTCVT FLERTDEDSY 
IVFTYRPCGC CSYVGRRGGG PQAISIGKNC DKFGIVVHEL GHVIGFWHEH TRPDRDRHVS 
IVRENIQPGQ EYNFLKMEVQ EVESLGETYD FDSIMHYARN TFSRGIFLDT IVPKYEVNGV 
KPSIGQRTRL SKGDIAQARK LYKCPACGET LQDSTGNFSS PEYPNGYSAH MHCVWRISVT 
PGEKIILNFT SMDLYRSRLC WYDYVEVRDG FWRKAPLRGR FCGGKLPEPI VSTDSRLWVE 
FRSSSNWVGK GFFAVYEAIC GGDVKKDNGH IQSPNYPDDY RPSKVCIWRI QVSEGFHVGL 
TFQSFEIERH DSCAYDYLEV RDGHSESSNL IGRYCGYEKP DDIKSTSSRL WLKFVSDGSI 
NKAGFAVNFF KEVDECSRPN RGGCEQRCLN TLGSYKCSCD PGYELAPDKR RCEAACGGFL 
TKLNGSITSP GWPKEYPPNK NCIWQLVAPT QYRISLQFDF FETEGNDVCK YDFVEVRSGL 
TADSKLHGKF CGSEKPEVIT SQYNNMRVEF KSDNTVSKKG FKAHFFSDKD ECSKDNGGCQ 
QDCVNTFGSY ECQCRSGFVL HDNKHDCKEA GCEHKVTSTS GTITSPNWPD KYPSKKECTW 
AISSTPGHRV KLTFVEMDIE SQPECAYDHL EVFDGRDAKA PVLGRFCGSK KPEPVLATGN 
RMFLRFYSDN SVQRKGFQAS HSTECGGQVR ADVKTKDLYS HAQFGDNNYP GGVDCEWVIV 
AEEGYGVELV FQTFEVEEET DCGYDYIELF DGYDSTAPRL GRYCGSGPPE EVYSAGDSVL 
VKFHSDDTIS KKGFHLRYTS TKFQDTLHSR K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bmp1

Associated with

Other Information

Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase. PubMed ID: 8174772

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid. PubMed ID: 8951074

Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase. PubMed ID: 20181949

Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. PubMed ID: 24419319

BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis. PubMed ID: 28068493