Details for: Bmp6

Gene ID: 12161

Symbol: Bmp6

Ensembl ID: ENSMUSG00000039004

Description: bone morphogenetic protein 6

Associated with

Other Information

Genular Protein ID: 576572943

Symbol: BMP6_MOUSE

Name: Bone morphogenetic protein 6

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8089189

Title: Recombinant Vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo.

PubMed ID: 8089189

DOI: 10.1083/jcb.126.6.1595

PubMed ID: 9069123

Title: Structure and sequence of the mouse Bmp6 gene.

PubMed ID: 9069123

DOI: 10.1007/s003359900391

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2734307

Title: Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily.

PubMed ID: 2734307

DOI: 10.1073/pnas.86.12.4554

PubMed ID: 9664685

Title: Mice lacking Bmp6 function.

PubMed ID: 9664685

DOI: 10.1002/(sici)1520-6408(1998)22:4<321::aid-dvg3>3.0.co;2-8

PubMed ID: 14623234

Title: Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot.

PubMed ID: 14623234

DOI: 10.1016/j.ydbio.2003.08.011

PubMed ID: 19252486

Title: BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.

PubMed ID: 19252486

DOI: 10.1038/ng.335

PubMed ID: 30097509

Title: Erythroferrone inhibits the induction of hepcidin by BMP6.

PubMed ID: 30097509

DOI: 10.1182/blood-2018-06-857995

PubMed ID: 31800957

Title: Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.

PubMed ID: 31800957

DOI: 10.1182/blood.2019002620

PubMed ID: 32464486

Title: Novel mutations in the bone morphogenetic protein 6 gene in patients with iron overload and non-homozygous genotype for the HFE p.Cys282Tyr mutation.

PubMed ID: 32464486

DOI: 10.1016/j.bcmd.2020.102444

Sequence Information:

  • Length: 510
  • Mass: 56432
  • Checksum: 910B68531289FCD2
  • Sequence:
  • MPGLGRRAQW LCWWWGLLCS CGPPPLRPPL PVAAAAAGGQ LLGAGGSPVR AEQPPPQSSS 
    SGFLYRRLKT HEKREMQKEI LSVLGLPHRP RPLHGLQQPQ PPVLPPQQQQ QQQQQQTARE 
    EPPPGRLKSA PLFMLDLYNA LSNDDEEDGA SEGVGQEPGS HGGASSSQLR QPSPGAAHSL 
    NRKSLLAPGP GGGASPLTSA QDSAFLNDAD MVMSFVNLVE YDKEFSPHQR HHKEFKFNLS 
    QIPEGEAVTA AEFRVYKDCV VGSFKNQTFL ISIYQVLQEH QHRDSDLFLL DTRVVWASEE 
    GWLEFDITAT SNLWVVTPQH NMGLQLSVVT RDGLHVNPRA AGLVGRDGPY DKQPFMVAFF 
    KVSEVHVRTT RSASSRRRQQ SRNRSTQSQD VSRGSGSSDY NGSELKTACK KHELYVSFQD 
    LGWQDWIIAP KGYAANYCDG ECSFPLNAHM NATNHAIVQT LVHLMNPEYV PKPCCAPTKL 
    NAISVLYFDD NSNVILKKYR NMVVRACGCH

Genular Protein ID: 3750352975

Symbol: Q8BRW3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 435
  • Mass: 48438
  • Checksum: E26CFE2180E20F76
  • Sequence:
  • MQKEILSVLG LQHRRGPLHG LQQRQPPVLP PQQQQQQQQQ QTAREEPPPG RLKSAPLFML 
    DLYNALSNDD EEDGASEGVG QEPGSHGGAS SSQLRQPSPG AAHSLNRKSL LAPGPGGGAS 
    PLTSAQDSAF LNDADMVMSF VNLVEYDKEF SPHQRHHKEF KFNLSQIPEG EAVTAAEFRV 
    YKDCVVGSFK NQTFLISIYQ VLQEHQHRDS DLFLLDTRVV WASEEGWLEF DITATSNLWV 
    VTPQHNMGLQ LSVVTRDGLH VNPRAAGLVG RDGPYDKQPF MVAFFKVSEV HVRTTRSASS 
    RRRQQSRNRS TQSQDVSRGS GSSDYNGSEL KTACKKHELY VSFQDLGWQD WIIAPKGYAA 
    NYCDGECSFP LNAHMNATNH AIVQTLVHLM NPEYVPKPCC APTKLNAISV LYFDDNSNVI 
    LKKYRNMVVR ACGCH

Genular Protein ID: 2322071121

Symbol: Q3UXB2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 460
  • Mass: 51300
  • Checksum: C74C18E2AC1D6170
  • Sequence:
  • AEQPPPQSSS SGFLYRRLKT HEKREMQKEI LSVLGLPHRP RPLHGLQQPQ PPVLPPQQQQ 
    QQQQQQTARE EPPPGRLKSA PLFMLDLYNA LSNDDEEDGA SEGVGQEPGS HGGASSSQLR 
    QPSPGAAHSL NRKSLLAPGP GGGASPLTSA QDSAFLNDAD MVMSFVNLVE YDKEFSPHQR 
    HHKEFKFNLS QIPEGEAVTA AEFRVYKDCV VGSFKNQTFL ISIYQVLQEH QHRDSDLFLL 
    DTRVVWASEE GWLEFDITAT SNLWVVTPQH NMGLQLSVVT RDGLHVNPRA AGLVGRDGPY 
    DKQPFMVAFF KVSEVHVRTT RSASSRRRQQ SRNRSTQSQD VSRGSGSSDY NGSELKTACK 
    KHELYVSFQD LGWQDWIIAP KGYAANYCDG ECSFPLNAHM NATNHAIVQT LVHLMNPEYV 
    PKPCCAPTKL NAISVLYFDD NSNVILKKYR NMVVRACGCH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.