Genular: Defining Cellular Identity and Function

Details for: Bsg

Gene ID: 12215

Symbol: Bsg

Ensembl ID: ENSMUSG00000023175

Description: basigin

Associated with

Aspirin adme
(R-MMU-9749641)
Basigin interactions
(R-MMU-210991)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Degradation of the extracellular matrix
(R-MMU-1474228)
Drug adme
(R-MMU-9748784)
Extracellular matrix organization
(R-MMU-1474244)
Hemostasis
(R-MMU-109582)
Integrin cell surface interactions
(R-MMU-216083)
Metabolism
(R-MMU-1430728)
Proton-coupled monocarboxylate transport
(R-MMU-433692)
Pyruvate metabolism
(R-MMU-70268)
Pyruvate metabolism and citric acid (tca) cycle
(R-MMU-71406)
Slc-mediated transmembrane transport
(R-MMU-425407)
The citric acid (tca) cycle and respiratory electron transport
(R-MMU-1428517)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-MMU-425366)
Transport of small molecules
(R-MMU-382551)
Acrosomal membrane
(GO:0002080)
Angiogenesis
(GO:0001525)
Axon guidance
(GO:0007411)
Carbohydrate binding
(GO:0030246)
Cell adhesion
(GO:0007155)
Cell differentiation
(GO:0030154)
Cell projection
(GO:0042995)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Endosome
(GO:0005768)
Endothelial tube morphogenesis
(GO:0061154)
Intracellular membrane-bounded organelle
(GO:0043231)
Mannose binding
(GO:0005537)
Membrane
(GO:0016020)
Neural retina development
(GO:0003407)
Neutrophil chemotaxis
(GO:0030593)
Photoreceptor cell maintenance
(GO:0045494)
Photoreceptor inner segment
(GO:0001917)
Photoreceptor outer segment
(GO:0001750)
Plasma membrane
(GO:0005886)
Positive regulation of endothelial cell migration
(GO:0010595)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of matrix metallopeptidase secretion
(GO:1904466)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Positive regulation of viral entry into host cell
(GO:0046598)
Protein binding
(GO:0005515)
Protein localization to plasma membrane
(GO:0072659)
Sarcolemma
(GO:0042383)
Signaling receptor activity
(GO:0038023)
Spermatogenesis
(GO:0007283)
Virus receptor activity
(GO:0001618)

Other Information

Proteins

Basigin

Genular Protein ID: 1503489913

Symbol: BASI_MOUSE

Name: Basigin

UniProtKB Accession Codes:

P18572 Q6LDB0 Q7TSC0

Database IDs:

Citations:

PubMed ID: 2361961

Title: Basigin, a new, broadly distributed member of the immunoglobulin superfamily, has strong homology with both the immunoglobulin V domain and the beta-chain of major histocompatibility complex class II antigen.

PubMed ID: 2361961

DOI: 10.1093/oxfordjournals.jbchem.a123045

PubMed ID: 2697642

Title: Cloning of cDNA for a novel mouse membrane glycoprotein (gp42): shared identity to histocompatibility antigens, immunoglobulins and neural-cell adhesion molecules.

PubMed ID: 2697642

DOI: 10.1016/0378-1119(89)90438-1

PubMed ID: 8333335

Title: Expression of the HT7 gene in blood-brain barrier.

PubMed ID: 8333335

DOI: 10.1007/978-1-4615-2920-0_33

PubMed ID: 8576084

Title: Structure of the mouse basigin gene, a unique member of the immunoglobulin superfamily.

PubMed ID: 8576084

DOI: 10.1093/oxfordjournals.jbchem.a124971

PubMed ID: 2032306

Title: Basigin, a new member of the immunoglobulin superfamily: genes in different mammalian species, glycosylation changes in the molecule from adult organs and possible variation in the N-terminal sequences.

PubMed ID: 2032306

DOI: 10.1247/csf.16.23

PubMed ID: 12939332

Title: Retina-specific expression of 5A11/Basigin-2, a member of the immunoglobulin gene superfamily.

PubMed ID: 12939332

DOI: 10.1167/iovs.02-0995

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12558975

Title: The immunoglobulin-superfamily molecule basigin is a binding protein for oligomannosidic carbohydrates: an anti-idiotypic approach.

PubMed ID: 12558975

DOI: 10.1046/j.1471-4159.2003.01537.x

PubMed ID: 10967074

Title: Retinal dysfunction in basigin deficiency.

PubMed ID: 10967074

PubMed ID: 11273674

Title: Retinal degeneration following failed photoreceptor maturation in 5A11/basigin null mice.

PubMed ID: 11273674

DOI: 10.1006/exer.2000.0974

PubMed ID: 11853760

Title: Inactivation of the Basigin gene impairs normal retinal development and maturation.

PubMed ID: 11853760

DOI: 10.1016/s0042-6989(01)00236-x

PubMed ID: 12601063

Title: Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse.

PubMed ID: 12601063

DOI: 10.1167/iovs.02-0552

PubMed ID: 12211060

Title: Basigin expression and hormonal regulation in mouse uterus during the peri-implantation period.

PubMed ID: 12211060

DOI: 10.1002/mrd.10128

PubMed ID: 11882021

Title: Behaviour of a sperm surface transmembrane glycoprotein basigin during epididymal maturation and its role in fertilization in mice.

PubMed ID: 11882021

DOI: 10.1530/rep.0.1230435

PubMed ID: 15037112

Title: Developmental analyses of 5A11/Basigin, 5A11/Basigin-2 and their putative binding partner MCT1 in the mouse eye.

PubMed ID: 15037112

DOI: 10.1016/j.exer.2003.12.004

PubMed ID: 15095333

Title: Basigin expression and regulation in mouse ovary during the sexual maturation and development of corpus luteum.

PubMed ID: 15095333

DOI: 10.1002/mrd.20060

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19656770

Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.

PubMed ID: 19656770

DOI: 10.1074/mcp.m900195-mcp200

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21792931

Title: Basigin interacts with both MCT1 and MCT2 in murine spermatozoa.

PubMed ID: 21792931

DOI: 10.1002/jcp.22949

PubMed ID: 23727514

Title: Basigin null mutant male mice are sterile and exhibit impaired interactions between germ cells and Sertoli cells.

PubMed ID: 23727514

DOI: 10.1016/j.ydbio.2013.05.023

PubMed ID: 25957687

Title: Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis.

PubMed ID: 25957687

DOI: 10.1016/j.cell.2015.03.023

PubMed ID: 27503893

Title: Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.

PubMed ID: 27503893

DOI: 10.1073/pnas.1610403113

Sequence Information:

Length: 389
Mass: 42445
Checksum: B1E484C3386BEB20
Sequence:

MAAALLLALA FTLLSGQGAC AAAGFLKAPL SQERWAGGSV VLHCEAVGSP IPEIQWWFEG 
NAPNDSCSQL WDGARLDRVH IHAAYRQHAA SSLSVDGLTA EDTGTYECRA SSDPDRNHLT 
RPPRVKWVRA QASVVVLEPG TIQTSVQEVN SKTQLTCSLN SSGVDIVGHR WMRGGKVLQE 
DTLPDLHTKY IVDADDRSGE YSCIFLPEPV GRSEINVEGP PRIKVGKKSE HSSEGELAKL 
VCKSDASYPP ITDWFWFKTS DTGEEEAITN STEANGKYVV VSTPEKSQLT ISNLDVNVDP 
GTYVCNATNA QGTTRETISL RVRSRMAALW PFLGIVAEVL VLVTIIFIYE KRRKPDQTLD 
EDDPGAAPLK GSGTHMNDKD KNVRQRNAT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bsg

Associated with

Other Information

Basigin, a new, broadly distributed member of the immunoglobulin superfamily, has strong homology with both the immunoglobulin V domain and the beta-chain of major histocompatibility complex class II antigen. PubMed ID: 2361961

Cloning of cDNA for a novel mouse membrane glycoprotein (gp42): shared identity to histocompatibility antigens, immunoglobulins and neural-cell adhesion molecules. PubMed ID: 2697642

Expression of the HT7 gene in blood-brain barrier. PubMed ID: 8333335

Structure of the mouse basigin gene, a unique member of the immunoglobulin superfamily. PubMed ID: 8576084

Basigin, a new member of the immunoglobulin superfamily: genes in different mammalian species, glycosylation changes in the molecule from adult organs and possible variation in the N-terminal sequences. PubMed ID: 2032306

Retina-specific expression of 5A11/Basigin-2, a member of the immunoglobulin gene superfamily. PubMed ID: 12939332

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The immunoglobulin-superfamily molecule basigin is a binding protein for oligomannosidic carbohydrates: an anti-idiotypic approach. PubMed ID: 12558975

Retinal dysfunction in basigin deficiency. PubMed ID: 10967074

Retinal degeneration following failed photoreceptor maturation in 5A11/basigin null mice. PubMed ID: 11273674

Inactivation of the Basigin gene impairs normal retinal development and maturation. PubMed ID: 11853760

Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse. PubMed ID: 12601063

Basigin expression and hormonal regulation in mouse uterus during the peri-implantation period. PubMed ID: 12211060

Behaviour of a sperm surface transmembrane glycoprotein basigin during epididymal maturation and its role in fertilization in mice. PubMed ID: 11882021

Developmental analyses of 5A11/Basigin, 5A11/Basigin-2 and their putative binding partner MCT1 in the mouse eye. PubMed ID: 15037112

Basigin expression and regulation in mouse ovary during the sexual maturation and development of corpus luteum. PubMed ID: 15095333

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. PubMed ID: 19656770

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Basigin interacts with both MCT1 and MCT2 in murine spermatozoa. PubMed ID: 21792931

Basigin null mutant male mice are sterile and exhibit impaired interactions between germ cells and Sertoli cells. PubMed ID: 23727514

Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis. PubMed ID: 25957687

Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure. PubMed ID: 27503893