Genular: Defining Cellular Identity and Function

Details for: Serping1

Gene ID: 12258

Symbol: Serping1

Ensembl ID: ENSMUSG00000023224

Description: serine (or cysteine) peptidase inhibitor, clade G, member 1

Associated with

Complement cascade
(R-MMU-166658)
Formation of fibrin clot (clotting cascade)
(R-MMU-140877)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Intrinsic pathway of fibrin clot formation
(R-MMU-140837)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Regulation of complement cascade
(R-MMU-977606)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Blood coagulation
(GO:0007596)
Collagen-containing extracellular matrix
(GO:0062023)
Complement activation, classical pathway
(GO:0006958)
Complement binding
(GO:0001848)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fibrinolysis
(GO:0042730)
Hemostasis
(GO:0007599)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Negative regulation of complement activation, lectin pathway
(GO:0001869)
Negative regulation of endopeptidase activity
(GO:0010951)
Negative regulation of peptidase activity
(GO:0010466)
Peptidase inhibitor activity
(GO:0030414)
Serine-type endopeptidase inhibitor activity
(GO:0004867)

Other Information

Proteins

Plasma protease C1 inhibitor

Genular Protein ID: 42253656

Symbol: IC1_MOUSE

Name: Plasma protease C1 inhibitor

UniProtKB Accession Codes:

P97290 A2ATR7 O88330 Q99M43 Q9QX09

Database IDs:

Citations:

PubMed ID: 9199246

Title: The sequence of a cDNA encoding functional murine C1-inhibitor protein.

PubMed ID: 9199246

DOI: 10.1016/s0167-4781(97)00056-0

PubMed ID: 9652403

Title: Molecular cloning, gene structure and expression profile of mouse C1 inhibitor.

PubMed ID: 9652403

DOI: 10.1046/j.1432-1327.1998.2540117.x

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16944957

Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PubMed ID: 16944957

DOI: 10.1021/pr060186m

PubMed ID: 17330941

Title: Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.

PubMed ID: 17330941

DOI: 10.1021/pr0604559

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 504
Mass: 55585
Checksum: B27BBDC05D318E62
Sequence:

MASRLTPLTL LLLLLAGDRA FSDPEATSHS TQDPLEAQAK SRESFPERDD SWSPPEPTVL 
PSTWPTTSVA ITITNDTMGK VANESFSQHS QPAAQLPTDS PGQPPLNSSS QPSTASDLPT 
QATTEPFCPE PLAQCSDSDR DSSEAKLSEA LTDFSVKLYH AFSATKMAKT NMAFSPFSIA 
SLLTQVLLGA GDSTKSNLES ILSYPKDFAC VHQALKGFSS KGVTSVSQIF HSPDLAIRDT 
YVNASQSLYG SSPRVLGPDS AANLELINTW VAENTNHKIR KLLDSLPSDT CLVLLNAVYL 
SAKWKITFEP KKMMAPFFYK NSMIKVPMMS SVKYPVAQFD DHTLKAKVGQ LQLSHNLSFV 
IVVPVFPKHQ LKDVEKALNP TVFKAIMKKL ELSKFLPTYL TMPHIKVKSS QDMLSVMEKL 
EFFDFTYDLN LCGLTEDPDL QVSAMKHETV LELTESGVEA AAASAISFGR SLPIFEVQRP 
FLFLLWDQQH RFPVFMGRVY DPRG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Serping1

Associated with

Other Information

The sequence of a cDNA encoding functional murine C1-inhibitor protein. PubMed ID: 9199246

Molecular cloning, gene structure and expression profile of mouse C1 inhibitor. PubMed ID: 9652403

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Proteome-wide characterization of N-glycosylation events by diagonal chromatography. PubMed ID: 16944957

Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides. PubMed ID: 17330941

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079