Genular: Defining Cellular Identity and Function

Details for: C3ar1

Gene ID: 12267

Symbol: C3ar1

Ensembl ID: ENSMUSG00000040552

Description: complement component 3a receptor 1

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Complement cascade
(R-MMU-166658)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Peptide ligand-binding receptors
(R-MMU-375276)
Regulation of complement cascade
(R-MMU-977606)
Signaling by gpcr
(R-MMU-372790)
Calcium-mediated signaling
(GO:0019722)
Chemotaxis
(GO:0006935)
Complement component c3a binding
(GO:0001850)
Complement component c3a receptor activity
(GO:0004876)
Complement component c5a receptor activity
(GO:0004878)
Complement receptor activity
(GO:0004875)
Complement receptor mediated signaling pathway
(GO:0002430)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Inflammatory response
(GO:0006954)
Membrane
(GO:0016020)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of dna biosynthetic process
(GO:2000573)
Positive regulation of glomerular mesangial cell proliferation
(GO:0072126)
Positive regulation of macrophage chemotaxis
(GO:0010759)
Positive regulation of neutrophil chemotaxis
(GO:0090023)
Positive regulation of smooth muscle cell proliferation
(GO:0048661)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Regulation of blood pressure
(GO:0008217)
Signal transduction
(GO:0007165)
Tolerance induction to nonself antigen
(GO:0002462)

Other Information

Proteins

C3a anaphylatoxin chemotactic receptor

Genular Protein ID: 655103450

Symbol: C3AR_MOUSE

Name: C3a anaphylatoxin chemotactic receptor

UniProtKB Accession Codes:

O09047 O35951

Database IDs:

Citations:

PubMed ID: 9164946

Title: The mouse anaphylatoxin C3a receptor: molecular cloning, genomic organization, and functional expression.

PubMed ID: 9164946

PubMed ID: 9382922

Title: Cloning and functional characterization of the mouse C3a anaphylatoxin receptor gene.

PubMed ID: 9382922

DOI: 10.1007/s002510050327

PubMed ID: 9694514

Title: Cloning, expression, sequence determination, and chromosome localization of the mouse complement C3a anaphylatoxin receptor gene.

PubMed ID: 9694514

DOI: 10.1016/s0161-5890(98)00021-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25456411

Title: The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanism.

PubMed ID: 25456411

DOI: 10.1016/j.str.2014.10.001

Sequence Information:

Length: 477
Mass: 53576
Checksum: 9873F464A1520984
Sequence:

MESFDADTNS TDLHSRPLFQ PQDIASMVIL GLTCLLGLLG NGLVLWVAGV KMKTTVNTVW 
FLHLTLADFL CCLSLPFSLA HLILQGHWPY GLFLCKLIPS IIILNMFASV FLLTAISLDR 
CLIVHKPIWC QNHRNVRTAF AICGCVWVVA FVMCVPVFVY RDLFIMDNRS ICRYNFDSSR 
SYDYWDYVYK LSLPESNSTD NSTAQLTGHM NDRSAPSSVQ ARDYFWTVTT ALQSQPFLTS 
PEDSFSLDSA NQQPHYGGKP PNVLTAAVPS GFPVEDRKSN TLNADAFLSA HTELFPTASS 
GHLYPYDFQG DYVDQFTYDN HVPTPLMAIT ITRLVVGFLV PFFIMVICYS LIVFRMRKTN 
FTKSRNKTFR VAVAVVTVFF ICWTPYHLVG VLLLITDPES SLGEAVMSWD HMSIALASAN 
SCFNPFLYAL LGKDFRKKAR QSIKGILEAA FSEELTHSTN CTQDKASSKR NNMSTDV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: C3ar1

Associated with

Other Information

The mouse anaphylatoxin C3a receptor: molecular cloning, genomic organization, and functional expression. PubMed ID: 9164946

Cloning and functional characterization of the mouse C3a anaphylatoxin receptor gene. PubMed ID: 9382922

Cloning, expression, sequence determination, and chromosome localization of the mouse complement C3a anaphylatoxin receptor gene. PubMed ID: 9694514

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079