Genular: Defining Cellular Identity and Function

Details for: Calm1

Gene ID: 12313

Symbol: Calm1

Ensembl ID: ENSMUSG00000001175

Description: calmodulin 1

Associated with

Activation of ca-permeable kainate receptor
(R-MMU-451308)
Activation of kainate receptors upon glutamate binding
(R-MMU-451326)
Activation of nmda receptors and postsynaptic events
(R-MMU-442755)
Activation of rac1 downstream of nmdars
(R-MMU-9619229)
Adaptive immune system
(R-MMU-1280218)
Beta-catenin independent wnt signaling
(R-MMU-3858494)
C-type lectin receptors (clrs)
(R-MMU-5621481)
Ca-dependent events
(R-MMU-111996)
Ca2+ pathway
(R-MMU-4086398)
Calcineurin activates nfat
(R-MMU-2025928)
Calmodulin induced events
(R-MMU-111933)
Cam-pde 1 activation
(R-MMU-111957)
Camk iv-mediated phosphorylation of creb
(R-MMU-111932)
Cam pathway
(R-MMU-111997)
Cardiac conduction
(R-MMU-5576891)
Clec7a (dectin-1) induces nfat activation
(R-MMU-5607763)
Clec7a (dectin-1) signaling
(R-MMU-5607764)
Creb1 phosphorylation through the activation of camkii/camkk/camkiv cascasde
(R-MMU-442729)
Dag and ip3 signaling
(R-MMU-1489509)
Downstream signaling events of b cell receptor (bcr)
(R-MMU-1168372)
Enos activation
(R-MMU-203615)
Esr-mediated signaling
(R-MMU-8939211)
Extra-nuclear estrogen signaling
(R-MMU-9009391)
Fc epsilon receptor (fceri) signaling
(R-MMU-2454202)
Fceri mediated ca+2 mobilization
(R-MMU-2871809)
G-protein mediated events
(R-MMU-112040)
G alpha (i) signalling events
(R-MMU-418594)
Glycogen breakdown (glycogenolysis)
(R-MMU-70221)
Glycogen metabolism
(R-MMU-8982491)
Gpcr downstream signalling
(R-MMU-388396)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Inactivation, recovery and regulation of the phototransduction cascade
(R-MMU-2514859)
Innate immune system
(R-MMU-168249)
Inositol phosphate metabolism
(R-MMU-1483249)
Intracellular signaling by second messengers
(R-MMU-9006925)
Ion channel transport
(R-MMU-983712)
Ion homeostasis
(R-MMU-5578775)
Ionotropic activity of kainate receptors
(R-MMU-451306)
Ion transport by p-type atpases
(R-MMU-936837)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of cofactors
(R-MMU-8978934)
Metabolism of nitric oxide: nos3 activation and regulation
(R-MMU-202131)
Metabolism of proteins
(R-MMU-392499)
Metabolism of vitamins and cofactors
(R-MMU-196854)
Muscle contraction
(R-MMU-397014)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Opioid signalling
(R-MMU-111885)
Pka-mediated phosphorylation of creb
(R-MMU-111931)
Pka activation
(R-MMU-163615)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet calcium homeostasis
(R-MMU-418360)
Platelet degranulation
(R-MMU-114608)
Platelet homeostasis
(R-MMU-418346)
Plc beta mediated events
(R-MMU-112043)
Post-translational protein modification
(R-MMU-597592)
Post nmda receptor activation events
(R-MMU-438064)
Protein methylation
(R-MMU-8876725)
Raf/map kinase cascade
(R-MMU-5673001)
Raf activation
(R-MMU-5673000)
Ras processing
(R-MMU-9648002)
Reduction of cytosolic ca++ levels
(R-MMU-418359)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate iqgaps
(R-MMU-5626467)
Rho gtpases activate paks
(R-MMU-5627123)
Sensory perception
(R-MMU-9709957)
Signaling by gpcr
(R-MMU-372790)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signaling by the b cell receptor (bcr)
(R-MMU-983705)
Signaling by vegf
(R-MMU-194138)
Signaling by wnt
(R-MMU-195721)
Signal transduction
(R-MMU-162582)
Slc-mediated transmembrane transport
(R-MMU-425407)
Smooth muscle contraction
(R-MMU-445355)
Sodium/calcium exchangers
(R-MMU-425561)
Stimuli-sensing channels
(R-MMU-2672351)
Synthesis of ip3 and ip4 in the cytosol
(R-MMU-1855204)
Tetrahydrobiopterin (bh4) synthesis, recycling, salvage and regulation
(R-MMU-1474151)
The phototransduction cascade
(R-MMU-2514856)
Transmission across chemical synapses
(R-MMU-112315)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-MMU-425393)
Transport of small molecules
(R-MMU-382551)
Unblocking of nmda receptors, glutamate binding and activation
(R-MMU-438066)
Vegfa-vegfr2 pathway
(R-MMU-4420097)
Vegfr2 mediated vascular permeability
(R-MMU-5218920)
Visual phototransduction
(R-MMU-2187338)
Adenylate cyclase activator activity
(GO:0010856)
Calcium channel inhibitor activity
(GO:0019855)
Calcium ion binding
(GO:0005509)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)

Other Information

Proteins

CALM1_MOUSE
Q3UKW2_MOUSE

Genular Protein ID: 1532103233

Symbol: CALM1_MOUSE

Name: N/A

UniProtKB Accession Codes:

P0DP26 P02593 P62204 P70667 P99014 Q3TEH7 Q3THK5 Q3U6Z5 Q3U7C7 Q498A3 Q61379 Q61380 Q8BNC9 Q91VQ9 Q9D6G4

Database IDs:

Citations:

PubMed ID: 3384819

Title: The abundance of calmodulin mRNAs is regulated in phosphorylase kinase-deficient skeletal muscle.

PubMed ID: 3384819

DOI: 10.1016/s0021-9258(19)81579-x

PubMed ID: 12106288

Title: A collection of cDNA clones with specific expression patterns in mouse brain.

PubMed ID: 12106288

DOI: 10.1111/j.1460-9568.1990.tb00460.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16569770

Title: Gimap4 accelerates T-cell death.

PubMed ID: 16569770

DOI: 10.1182/blood-2005-11-4616

PubMed ID: 18650434

Title: S100A1 and calmodulin compete for the same binding site on ryanodine receptor.

PubMed ID: 18650434

DOI: 10.1074/jbc.m804432200

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 25380116

Title: A novel acrosomal protein, IQCF1, involved in sperm capacitation and the acrosome reaction.

PubMed ID: 25380116

DOI: 10.1111/andr.296

PubMed ID: 24569478

Title: Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment.

PubMed ID: 24569478

DOI: 10.7554/elife.01524

PubMed ID: 31088288

Title: The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and Calmodulin-Regulated Cysteine SUMO Protease.

PubMed ID: 31088288

DOI: 10.1089/ars.2019.7724

PubMed ID: 29025071

Title: The expression characteristics of FAM71D and its association with sperm motility.

PubMed ID: 29025071

DOI: 10.1093/humrep/dex290

PubMed ID: 36417862

Title: Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.

PubMed ID: 36417862

DOI: 10.1016/j.celrep.2022.111683

PubMed ID: 17151196

Title: Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features.

PubMed ID: 17151196

DOI: 10.1073/pnas.0609436103

PubMed ID: 23942337

Title: Structural basis for the modulation of the neuronal voltage-gated sodium channel NaV1.6 by calmodulin.

PubMed ID: 23942337

DOI: 10.1038/srep02435

Sequence Information:

Length: 149
Mass: 16838
Checksum: 6B4BC3FCDE10727B
Sequence:

MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG 
NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE 
EVDEMIREAD IDGDGQVNYE EFVQMMTAK

Genular Protein ID: 701591408

Symbol: Q3UKW2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UKW2

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 197
Mass: 21560
Checksum: F2F8D6F35AA1E483
Sequence:

MGRGEPGDVQ GLDRGLGVSS ATFRPPDQPS RESPLACGPL LPPGGRGAGA DQLTEEQIAE 
FKEAFSLFDK DGDGTITTKE LGTVMRSLGQ NPTEAELQDM INEVDADGNG TIDFPEFLTM 
MARKMKDTDS EEEIREAFRV FDKDGNGYIS AAELRHVMTN LGEKLTDEEV DEMIREADID 
GDGQVNYEEF VQMMTAK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Calm1

Associated with

Other Information

The abundance of calmodulin mRNAs is regulated in phosphorylase kinase-deficient skeletal muscle. PubMed ID: 3384819

A collection of cDNA clones with specific expression patterns in mouse brain. PubMed ID: 12106288

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Gimap4 accelerates T-cell death. PubMed ID: 16569770

S100A1 and calmodulin compete for the same binding site on ryanodine receptor. PubMed ID: 18650434

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

A novel acrosomal protein, IQCF1, involved in sperm capacitation and the acrosome reaction. PubMed ID: 25380116

Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment. PubMed ID: 24569478

The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and Calmodulin-Regulated Cysteine SUMO Protease. PubMed ID: 31088288

The expression characteristics of FAM71D and its association with sperm motility. PubMed ID: 29025071

Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella. PubMed ID: 36417862

Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features. PubMed ID: 17151196

Structural basis for the modulation of the neuronal voltage-gated sodium channel NaV1.6 by calmodulin. PubMed ID: 23942337

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Database document:

PubMed ID: 3384819

PubMed ID: 12106288

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 16569770

PubMed ID: 18650434

PubMed ID: 18034455

PubMed ID: 21183079

PubMed ID: 23806337

PubMed ID: 25380116

PubMed ID: 24569478

PubMed ID: 31088288

PubMed ID: 29025071

PubMed ID: 36417862

PubMed ID: 17151196

PubMed ID: 23942337

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 16141073

PubMed ID: 18034455

PubMed ID: 21183079

PubMed ID: 23806337