Genular: Defining Cellular Identity and Function

Details for: Canx

Gene ID: 12330

Symbol: Canx

Ensembl ID: ENSMUSG00000020368

Description: calnexin

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen presentation: folding, assembly and peptide loading of class i mhc
(R-MMU-983170)
Asparagine n-linked glycosylation
(R-MMU-446203)
Calnexin/calreticulin cycle
(R-MMU-901042)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Interleukin-12 family signaling
(R-MMU-447115)
Interleukin-27 signaling
(R-MMU-9020956)
Interleukin-35 signalling
(R-MMU-8984722)
Metabolism of proteins
(R-MMU-392499)
Mhc class ii antigen presentation
(R-MMU-2132295)
N-glycan trimming in the er and calnexin/calreticulin cycle
(R-MMU-532668)
Post-translational protein modification
(R-MMU-597592)
Signaling by interleukins
(R-MMU-449147)
Apolipoprotein binding
(GO:0034185)
Axon
(GO:0030424)
Calcium ion binding
(GO:0005509)
Carbohydrate binding
(GO:0030246)
Clathrin-dependent endocytosis
(GO:0072583)
Dendrite cytoplasm
(GO:0032839)
Dendritic spine
(GO:0043197)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum quality control compartment
(GO:0044322)
Erad pathway
(GO:0036503)
Glutamatergic synapse
(GO:0098978)
Ionotropic glutamate receptor binding
(GO:0035255)
Lumenal side of endoplasmic reticulum membrane
(GO:0098553)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondria-associated endoplasmic reticulum membrane
(GO:0044233)
Myelin sheath
(GO:0043209)
Neuronal cell body
(GO:0043025)
Nuclear membrane
(GO:0031965)
Postsynaptic membrane
(GO:0045211)
Presynapse
(GO:0098793)
Presynaptic active zone membrane
(GO:0048787)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Ribosome
(GO:0005840)
Smooth endoplasmic reticulum
(GO:0005790)
Synapse
(GO:0045202)
Synaptic vesicle endocytosis
(GO:0048488)
Unfolded protein binding
(GO:0051082)

Other Information

Proteins

Calnexin

Genular Protein ID: 492224902

Symbol: CALX_MOUSE

Name: Calnexin

UniProtKB Accession Codes:

P35564

Database IDs:

Citations:

PubMed ID: 8136357

Title: Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5.

PubMed ID: 8136357

DOI: 10.1021/bi00177a013

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 8148318

Title: Class II histocompatibility molecules associate with calnexin during assembly in the endoplasmic reticulum.

PubMed ID: 8148318

DOI: 10.1093/intimm/6.1.101

PubMed ID: 7628443

Title: The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes.

PubMed ID: 7628443

DOI: 10.1002/j.1460-2075.1995.tb07348.x

PubMed ID: 17622165

Title: A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.

PubMed ID: 17622165

DOI: 10.1021/pr070122r

PubMed ID: 17114649

Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PubMed ID: 17114649

DOI: 10.1074/mcp.m600046-mcp200

PubMed ID: 17208939

Title: Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

PubMed ID: 17208939

DOI: 10.1074/mcp.m600218-mcp200

PubMed ID: 18630941

Title: Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

PubMed ID: 18630941

DOI: 10.1021/pr800223m

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20945367

Title: Identification of heat shock protein 5, calnexin and integral membrane protein 2B as Adam7-interacting membrane proteins in mouse sperm.

PubMed ID: 20945367

DOI: 10.1002/jcp.22444

PubMed ID: 21747946

Title: Enhanced clathrin-dependent endocytosis in the absence of calnexin.

PubMed ID: 21747946

DOI: 10.1371/journal.pone.0021678

PubMed ID: 32783947

Title: NACHO Engages N-Glycosylation ER Chaperone Pathways for alpha7 Nicotinic Receptor Assembly.

PubMed ID: 32783947

DOI: 10.1016/j.celrep.2020.108025

Sequence Information:

Length: 591
Mass: 67278
Checksum: 0D9F8FE03434BADC
Sequence:

MEGKWLLCLL LVLGTAAVEA HDGHDDDAID IEDDLDDVIE EVEDSKSKSD ASTPPSPKVT 
YKAPVPTGEV YFADSFDRGS LSGWILSKAK KDDTDDEIAK YDGKWEVDEM KETKLPGDKG 
LVLMSRAKHH AISAKLNKPF LFDTKPLIVQ YEVNFQNGIE CGGAYVKLLS KTAELSLDQF 
HDKTPYTIMF GPDKCGEDYK LHFIFRHKNP KTGVYEEKHA KRPDADLKTY FTDKKTHLYT 
LILNPDNSFE ILVDQSVVNS GNLLNDMTPP VNPSREIEDP EDRKPEDWDE RPKIADPDAV 
KPDDWDEDAP SKIPDEEATK PEGWLDDEPE YIPDPDAEKP EDWDEDMDGE WEAPQIANPK 
CESAPGCGVW QRPMIDNPNY KGKWKPPMID NPNYQGIWKP RKIPNPDFFE DLEPFKMTPF 
SAIGLELWSM TSDIFFDNFI ISGDRRVVDD WANDGWGLKK AADGAAEPGV VLQMLEAAEE 
RPWLWVVYIL TVALPVFLVI LFCCSGKKQS NAMEYKKTDA PQPDVKDEEG KEEEKNKRDE 
EEEEEKLEEK QKSDAEEDGV TGSQDEEDSK PKAEEDEILN RSPRNRKPRR E

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Canx

Associated with

Other Information

Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5. PubMed ID: 8136357

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Class II histocompatibility molecules associate with calnexin during assembly in the endoplasmic reticulum. PubMed ID: 8148318

The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes. PubMed ID: 7628443

A differential phosphoproteomic analysis of retinoic acid-treated P19 cells. PubMed ID: 17622165

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. PubMed ID: 17114649

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. PubMed ID: 17208939

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. PubMed ID: 18630941

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Identification of heat shock protein 5, calnexin and integral membrane protein 2B as Adam7-interacting membrane proteins in mouse sperm. PubMed ID: 20945367

Enhanced clathrin-dependent endocytosis in the absence of calnexin. PubMed ID: 21747946

NACHO Engages N-Glycosylation ER Chaperone Pathways for alpha7 Nicotinic Receptor Assembly. PubMed ID: 32783947