Genular: Defining Cellular Identity and Function

Details for: Capzb

Gene ID: 12345

Symbol: Capzb

Ensembl ID: ENSMUSG00000028745

Description: capping actin protein of muscle Z-line subunit beta

Associated with

Adaptive immune system
(R-MMU-1280218)
Asparagine n-linked glycosylation
(R-MMU-446203)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Copi-independent golgi-to-er retrograde traffic
(R-MMU-6811436)
Copi-mediated anterograde transport
(R-MMU-6807878)
Er to golgi anterograde transport
(R-MMU-199977)
Factors involved in megakaryocyte development and platelet production
(R-MMU-983231)
Golgi-to-er retrograde transport
(R-MMU-8856688)
Hemostasis
(R-MMU-109582)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-MMU-3371497)
Immune system
(R-MMU-168256)
Intra-golgi and retrograde golgi-to-er traffic
(R-MMU-6811442)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Mhc class ii antigen presentation
(R-MMU-2132295)
Post-translational protein modification
(R-MMU-597592)
Rhod gtpase cycle
(R-MMU-9013405)
Rhof gtpase cycle
(R-MMU-9035034)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Vesicle-mediated transport
(R-MMU-5653656)
Actin binding
(GO:0003779)
Actin cytoskeleton organization
(GO:0030036)
Actin filament binding
(GO:0051015)
Actin filament capping
(GO:0051693)
Actin polymerization or depolymerization
(GO:0008154)
Asymmetric synapse
(GO:0032279)
Barbed-end actin filament capping
(GO:0051016)
Brush border
(GO:0005903)
Cell morphogenesis
(GO:0000902)
Cell projection organization
(GO:0030030)
Cortical cytoskeleton
(GO:0030863)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytoskeleton organization
(GO:0007010)
Cytosol
(GO:0005829)
Dendritic spine
(GO:0043197)
F-actin capping protein complex
(GO:0008290)
Hippocampal mossy fiber to ca3 synapse
(GO:0098686)
Lamellipodium
(GO:0030027)
Lamellipodium assembly
(GO:0030032)
Membrane
(GO:0016020)
Negative regulation of filopodium assembly
(GO:0051490)
Neuronal cell body
(GO:0043025)
Postsynaptic density
(GO:0014069)
Protein binding
(GO:0005515)
Regulation of cell morphogenesis
(GO:0022604)
Regulation of lamellipodium assembly
(GO:0010591)
Schaffer collateral - ca1 synapse
(GO:0098685)
Sperm connecting piece
(GO:0097224)
Wash complex
(GO:0071203)

Other Information

Proteins

F-actin-capping protein subunit beta
Q923G3_MOUSE

Genular Protein ID: 3610938837

Symbol: CAPZB_MOUSE

Name: F-actin-capping protein subunit beta

UniProtKB Accession Codes:

P47757 A2AMV7

Database IDs:

Citations:

PubMed ID: 7929588

Title: Differential localization and sequence analysis of capping protein beta-subunit isoforms of vertebrates.

PubMed ID: 7929588

DOI: 10.1083/jcb.127.2.453

PubMed ID: 19341723

Title: A missense mutation in the Capza3 gene and disruption of F-actin organization in spermatids of repro32 infertile male mice.

PubMed ID: 19341723

DOI: 10.1016/j.ydbio.2009.03.020

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 277
Mass: 31345
Checksum: C4409B1F9E014033
Sequence:

MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL 
LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY 
LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN 
KSGSGTMNLG GSLTRQMEKD ETVSDCSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV 
NGLRSLDAIP DNHKFKQLQR ELSQVLTQRQ VYIQPDN

Genular Protein ID: 1820670305

Symbol: Q923G3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q923G3

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 33571120

Title: The structure of the actin filament uncapping complex mediated by twinfilin. .

PubMed ID: 33571120

DOI: 10.1126/sciadv.abd5271

Sequence Information:

Length: 272
Mass: 30629
Checksum: E6466A68B1254FD0
Sequence:

MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL 
LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY 
LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN 
KSGSGTMNLG GSLTRQMEKD ETVSDCSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV 
NGLRSVQTFA DKSKQEALKN DLVEALKRKQ QC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Capzb

Associated with

Other Information

Differential localization and sequence analysis of capping protein beta-subunit isoforms of vertebrates. PubMed ID: 7929588

A missense mutation in the Capza3 gene and disruption of F-actin organization in spermatids of repro32 infertile male mice. PubMed ID: 19341723

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

The structure of the actin filament uncapping complex mediated by twinfilin. . PubMed ID: 33571120