Genular: Defining Cellular Identity and Function

Details for: Cat

Gene ID: 12359

Symbol: Cat

Ensembl ID: ENSMUSG00000027187

Description: catalase

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Peroxisomal protein import
(R-MMU-9033241)
Protein localization
(R-MMU-9609507)
Aerobic respiration
(GO:0009060)
Aminoacylase activity
(GO:0004046)
Antioxidant activity
(GO:0016209)
Catalase activity
(GO:0004096)
Catalase complex
(GO:0062151)
Cellular detoxification of hydrogen peroxide
(GO:0061692)
Cellular oxidant detoxification
(GO:0098869)
Cholesterol metabolic process
(GO:0008203)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Enzyme binding
(GO:0019899)
Extracellular space
(GO:0005615)
Heme binding
(GO:0020037)
Hemoglobin metabolic process
(GO:0020027)
Hydrogen peroxide catabolic process
(GO:0042744)
Identical protein binding
(GO:0042802)
Intracellular membrane-bounded organelle
(GO:0043231)
Kidney development
(GO:0001822)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Nadp binding
(GO:0050661)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of nf-kappab transcription factor activity
(GO:0032088)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on peroxide as acceptor
(GO:0016684)
Peroxidase activity
(GO:0004601)
Peroxisomal matrix
(GO:0005782)
Peroxisomal membrane
(GO:0005778)
Peroxisome
(GO:0005777)
Positive regulation of cell division
(GO:0051781)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Protein-containing complex
(GO:0032991)
Protein homodimerization activity
(GO:0042803)
Response to hydrogen peroxide
(GO:0042542)
Response to hypoxia
(GO:0001666)
Response to oxidative stress
(GO:0006979)
Response to reactive oxygen species
(GO:0000302)
Triglyceride metabolic process
(GO:0006641)
Ureteric bud development
(GO:0001657)
Uv protection
(GO:0009650)

Other Information

Proteins

Catalase

Genular Protein ID: 3222505324

Symbol: CATA_MOUSE

Name: Catalase

UniProtKB Accession Codes:

P24270 Q3TXQ6

Database IDs:

Citations:

PubMed ID: 2268310

Title: Molecular analysis of an acatalasemic mouse mutant.

PubMed ID: 2268310

DOI: 10.1016/s0006-291x(05)80891-5

PubMed ID: 2395665

Title: Nucleotide and deduced amino acid sequences of mouse catalase: molecular analysis of a low activity mutant.

PubMed ID: 2395665

DOI: 10.1093/nar/18.16.4941

PubMed ID: 8088826

Title: Complete cDNA and 5' genomic sequences and multilevel regulation of the mouse catalase gene.

PubMed ID: 8088826

DOI: 10.1006/geno.1994.1273

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3654595

Title: Isolation of a cDNA clone for murine catalase and analysis of an acatalasemic mutant.

PubMed ID: 3654595

DOI: 10.1016/s0021-9258(18)45143-5

PubMed ID: 17208939

Title: Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

PubMed ID: 17208939

DOI: 10.1074/mcp.m600218-mcp200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

Length: 527
Mass: 59795
Checksum: 4D86F3C9D1A3DF9E
Sequence:

MSDSRDPASD QMKQWKEQRA SQRPDVLTTG GGNPIGDKLN IMTAGSRGPL LVQDVVFTDE 
MAHFDRERIP ERVVHAKGAG AFGYFEVTHD ITRYSKAKVF EHIGKRTPIA VRFSTVTGES 
GSADTVRDPR GFAVKFYTED GNWDLVGNNT PIFFIRDAIL FPSFIHSQKR NPQTHLKDPD 
MVWDFWSLRP ESLHQVSFLF SDRGIPDGHR HMNGYGSHTF KLVNADGEAV YCKFHYKTDQ 
GIKNLPVGEA GRLAQEDPDY GLRDLFNAIA NGNYPSWTFY IQVMTFKEAE TFPFNPFDLT 
KVWPHKDYPL IPVGKLVLNK NPVNYFAEVE QMAFDPSNMP PGIEPSPDKM LQGRLFAYPD 
THRHRLGPNY LQIPVNCPYR ARVANYQRDG PMCMHDNQGG APNYYPNSFS APEQQRSALE 
HSVQCAVDVK RFNSANEDNV TQVRTFYTKV LNEEERKRLC ENIAGHLKDA QLFIQKKAVK 
NFTDVHPDYG ARIQALLDKY NAEKPKNAIH TYTQAGSHMA AKGKANL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cat

Associated with

Other Information

Molecular analysis of an acatalasemic mouse mutant. PubMed ID: 2268310

Nucleotide and deduced amino acid sequences of mouse catalase: molecular analysis of a low activity mutant. PubMed ID: 2395665

Complete cDNA and 5' genomic sequences and multilevel regulation of the mouse catalase gene. PubMed ID: 8088826

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Isolation of a cDNA clone for murine catalase and analysis of an acatalasemic mutant. PubMed ID: 3654595

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. PubMed ID: 17208939

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753