Details for: CCR7

Gene ID: 1236

Symbol: CCR7

Ensembl ID: ENSG00000126353

Description: C-C motif chemokine receptor 7

Associated with

  • Chemokine receptors bind chemokines
    (R-HSA-380108)
  • Class a/1 (rhodopsin-like receptors)
    (R-HSA-373076)
  • G alpha (i) signalling events
    (R-HSA-418594)
  • Gpcr downstream signalling
    (R-HSA-388396)
  • Gpcr ligand binding
    (R-HSA-500792)
  • Peptide ligand-binding receptors
    (R-HSA-375276)
  • Signaling by gpcr
    (R-HSA-372790)
  • Signal transduction
    (R-HSA-162582)
  • C-c chemokine receptor activity
    (GO:0016493)
  • C-c motif chemokine 19 receptor activity
    (GO:0038117)
  • C-c motif chemokine 21 receptor activity
    (GO:0038121)
  • Calcium-mediated signaling
    (GO:0019722)
  • Cell chemotaxis
    (GO:0060326)
  • Cell surface
    (GO:0009986)
  • Cellular response to cytokine stimulus
    (GO:0071345)
  • Chemokine (c-c motif) ligand 19 binding
    (GO:0035757)
  • Chemokine (c-c motif) ligand 19 signaling pathway
    (GO:0038115)
  • Chemokine (c-c motif) ligand 21 binding
    (GO:0035758)
  • Chemokine (c-c motif) ligand 21 signaling pathway
    (GO:0038116)
  • Dendritic cell chemotaxis
    (GO:0002407)
  • Establishment of t cell polarity
    (GO:0001768)
  • External side of plasma membrane
    (GO:0009897)
  • G protein-coupled receptor activity
    (GO:0004930)
  • G protein-coupled receptor signaling pathway
    (GO:0007186)
  • Homeostasis of number of cells
    (GO:0048872)
  • Immune response
    (GO:0006955)
  • Inflammatory response
    (GO:0006954)
  • Lymphocyte migration into lymph node
    (GO:0097022)
  • Mature conventional dendritic cell differentiation
    (GO:0097029)
  • Mitochondrion
    (GO:0005739)
  • Myeloid dendritic cell chemotaxis
    (GO:0002408)
  • Negative regulation of dendritic cell apoptotic process
    (GO:2000669)
  • Negative regulation of interleukin-12 production
    (GO:0032695)
  • Negative thymic t cell selection
    (GO:0045060)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of actin filament polymerization
    (GO:0030838)
  • Positive regulation of canonical nf-kappab signal transduction
    (GO:0043123)
  • Positive regulation of cell-matrix adhesion
    (GO:0001954)
  • Positive regulation of cell adhesion
    (GO:0045785)
  • Positive regulation of cell motility
    (GO:2000147)
  • Positive regulation of cytosolic calcium ion concentration
    (GO:0007204)
  • Positive regulation of dendritic cell antigen processing and presentation
    (GO:0002606)
  • Positive regulation of dendritic cell chemotaxis
    (GO:2000510)
  • Positive regulation of erk1 and erk2 cascade
    (GO:0070374)
  • Positive regulation of filopodium assembly
    (GO:0051491)
  • Positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
    (GO:2000526)
  • Positive regulation of humoral immune response
    (GO:0002922)
  • Positive regulation of hypersensitivity
    (GO:0002885)
  • Positive regulation of immunological synapse formation
    (GO:2000522)
  • Positive regulation of interleukin-12 production
    (GO:0032735)
  • Positive regulation of jnk cascade
    (GO:0046330)
  • Positive regulation of neutrophil chemotaxis
    (GO:0090023)
  • Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051897)
  • Positive regulation of protein kinase activity
    (GO:0045860)
  • Positive regulation of pseudopodium assembly
    (GO:0031274)
  • Positive regulation of t cell costimulation
    (GO:2000525)
  • Positive regulation of t cell receptor signaling pathway
    (GO:0050862)
  • Regulation of dendritic cell dendrite assembly
    (GO:2000547)
  • Regulation of interleukin-1 beta production
    (GO:0032651)
  • Regulation of type ii interferon production
    (GO:0032649)
  • Release of sequestered calcium ion into cytosol
    (GO:0051209)
  • Response to lipopolysaccharide
    (GO:0032496)
  • Response to nitric oxide
    (GO:0071731)
  • Response to prostaglandin e
    (GO:0034695)
  • Ruffle organization
    (GO:0031529)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 44.7137
    Cell Significance Index: -6.9600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 28.5834
    Cell Significance Index: -7.2500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 17.9392
    Cell Significance Index: -7.3900
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 6.1596
    Cell Significance Index: 105.8200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.7342
    Cell Significance Index: -7.0700
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 5.2728
    Cell Significance Index: 52.8700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.2775
    Cell Significance Index: -8.7800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.5896
    Cell Significance Index: 40.0700
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 2.3725
    Cell Significance Index: 10.6100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.5400
    Cell Significance Index: -4.7300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.6861
    Cell Significance Index: 20.1500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.4835
    Cell Significance Index: 12.9100
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.3314
    Cell Significance Index: 1.0100
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 0.2287
    Cell Significance Index: 2.0000
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.2201
    Cell Significance Index: 1.2000
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.0384
    Cell Significance Index: 0.1600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0251
    Cell Significance Index: 13.6900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0226
    Cell Significance Index: 2.6700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0225
    Cell Significance Index: 1.1400
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.0044
    Cell Significance Index: 0.0400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0015
    Cell Significance Index: -2.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0050
    Cell Significance Index: -0.7300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0061
    Cell Significance Index: -11.2900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0074
    Cell Significance Index: -11.4300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0076
    Cell Significance Index: -5.7400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0099
    Cell Significance Index: -0.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0102
    Cell Significance Index: -4.5000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0118
    Cell Significance Index: -7.3500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0133
    Cell Significance Index: -9.7600
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: -0.0140
    Cell Significance Index: -0.0700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0146
    Cell Significance Index: -9.2600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0156
    Cell Significance Index: -8.8200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0157
    Cell Significance Index: -2.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0190
    Cell Significance Index: -6.8300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0202
    Cell Significance Index: -9.1700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0287
    Cell Significance Index: -1.2500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0298
    Cell Significance Index: -8.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0301
    Cell Significance Index: -5.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0343
    Cell Significance Index: -6.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0348
    Cell Significance Index: -6.2800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0395
    Cell Significance Index: -8.3300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0435
    Cell Significance Index: -2.8100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0489
    Cell Significance Index: -2.0000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0499
    Cell Significance Index: -6.8500
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0505
    Cell Significance Index: -0.4800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0515
    Cell Significance Index: -8.8000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0517
    Cell Significance Index: -0.7400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0527
    Cell Significance Index: -6.1400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0544
    Cell Significance Index: -6.6900
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: -0.0643
    Cell Significance Index: -0.5600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0643
    Cell Significance Index: -8.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0690
    Cell Significance Index: -7.1800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0720
    Cell Significance Index: -1.8400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0741
    Cell Significance Index: -5.2400
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0745
    Cell Significance Index: -1.0900
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.0764
    Cell Significance Index: -0.5500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0765
    Cell Significance Index: -1.3000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0784
    Cell Significance Index: -8.0100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0800
    Cell Significance Index: -9.1700
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.1020
    Cell Significance Index: -0.9800
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.1080
    Cell Significance Index: -1.0100
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.1099
    Cell Significance Index: -1.1400
  • Cell Name: naive T cell (CL0000898)
    Fold Change: -0.1101
    Cell Significance Index: -1.0000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1109
    Cell Significance Index: -6.9900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1111
    Cell Significance Index: -7.4700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1119
    Cell Significance Index: -5.2600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1127
    Cell Significance Index: -8.6500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1182
    Cell Significance Index: -8.8100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1313
    Cell Significance Index: -8.0500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1342
    Cell Significance Index: -3.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1438
    Cell Significance Index: -7.4700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1490
    Cell Significance Index: -9.1600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1502
    Cell Significance Index: -8.4300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1535
    Cell Significance Index: -4.2900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1613
    Cell Significance Index: -8.4700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1751
    Cell Significance Index: -4.5000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1864
    Cell Significance Index: -8.4500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1974
    Cell Significance Index: -10.2800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1997
    Cell Significance Index: -9.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2010
    Cell Significance Index: -8.8900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2017
    Cell Significance Index: -5.4900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2095
    Cell Significance Index: -7.3400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2119
    Cell Significance Index: -7.4500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2248
    Cell Significance Index: -7.1100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2248
    Cell Significance Index: -7.3600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2254
    Cell Significance Index: -8.2800
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.2258
    Cell Significance Index: -2.0900
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.2264
    Cell Significance Index: -3.0800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2323
    Cell Significance Index: -7.4000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2356
    Cell Significance Index: -8.9200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2465
    Cell Significance Index: -5.1600
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: -0.2551
    Cell Significance Index: -2.5700
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.2600
    Cell Significance Index: -3.0700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2629
    Cell Significance Index: -7.5000
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.2730
    Cell Significance Index: -3.4500
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.2735
    Cell Significance Index: -2.9100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2744
    Cell Significance Index: -7.2200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2747
    Cell Significance Index: -7.3600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2852
    Cell Significance Index: -9.9100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2923
    Cell Significance Index: -8.3800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Expression**: CCR7 is widely expressed on various cell types, including thymocytes, T cells, B cells, endothelial cells, and dendritic cells. 2. **Ligands**: CCR7 binds to two chemokines, CCL19 and CCL21, which are expressed on endothelial cells and other cells in lymphoid organs. 3. **Signaling**: CCR7 triggers a signaling cascade that regulates cell migration, chemotaxis, and cell-cell interactions. 4. **Function**: CCR7 plays a crucial role in the regulation of immune responses, inflammation, and tissue homeostasis. 5. **Regulation**: CCR7 is regulated by various signaling pathways, including calcium-mediated signaling, G protein-coupled receptor signaling, and phosphatidylinositol 3-kinase/protein kinase B signaling. **Pathways and Functions** 1. **Cell Migration**: CCR7 is involved in the migration of immune cells, particularly T cells and dendritic cells, from the bloodstream to lymphoid organs. 2. **Chemotaxis**: CCR7 regulates cell chemotaxis, which is the directional movement of cells in response to chemical stimuli. 3. **Cell-Cell Interactions**: CCR7 regulates cell-cell interactions, including adhesion, migration, and signaling between immune cells and endothelial cells. 4. **Immune Response**: CCR7 plays a crucial role in the regulation of immune responses, including the activation of T cells, B cells, and dendritic cells. 5. **Inflammation**: CCR7 is involved in the regulation of inflammation, including the recruitment of immune cells to sites of inflammation. 6. **Tissue Homeostasis**: CCR7 regulates tissue homeostasis, including the maintenance of immune cell populations and the regulation of immune responses. **Clinical Significance** 1. **Cancer**: CCR7 is overexpressed in various types of cancer, including lymphoma, leukemia, and melanoma, and has been associated with poor prognosis. 2. **Inflammatory Diseases**: CCR7 is involved in the regulation of inflammatory responses, and its blockade has been proposed as a therapeutic strategy for treating inflammatory diseases, such as rheumatoid arthritis and multiple sclerosis. 3. **Autoimmune Diseases**: CCR7 is involved in the regulation of immune responses, and its blockade has been proposed as a therapeutic strategy for treating autoimmune diseases, such as type 1 diabetes and multiple sclerosis. 4. **Vaccine Development**: CCR7 has been identified as a potential target for vaccine development, particularly for vaccines against infectious diseases, such as HIV and tuberculosis. In conclusion, CCR7 is a critical component of the immune system, playing a pivotal role in the regulation of immune responses, inflammation, and tissue homeostasis. Its expression, ligands, signaling, and functions have been characterized, and its clinical significance has been highlighted. Further research is needed to fully understand the role of CCR7 in the immune system and to develop therapeutic strategies that target this receptor.

Genular Protein ID: 4268403927

Symbol: CCR7_HUMAN

Name: C-C chemokine receptor type 7

UniProtKB Accession Codes:

P32248

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 1 ExpressionAtlas 1 GO 55 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 5 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8383238

Title: Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors.

PubMed ID: 8383238

DOI: 10.1128/jvi.67.4.2209-2220.1993

PubMed ID: 7851893

Title: Cloning of human and mouse EBI1, a lymphoid-specific G-protein-coupled receptor encoded on human chromosome 17q12-q21.2.

PubMed ID: 7851893

DOI: 10.1006/geno.1994.1553

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 378
  • Mass: 42874
  • Checksum: D4CB4213841A1BD4
  • Sequence:
    • MDLGKPMKSV LVVALLVIFQ VCLCQDEVTD DYIGDNTTVD YTLFESLCSK KDVRNFKAWF 
LPIMYSIICF VGLLGNGLVV LTYIYFKRLK TMTDTYLLNL AVADILFLLT LPFWAYSAAK 
SWVFGVHFCK LIFAIYKMSF FSGMLLLLCI SIDRYVAIVQ AVSAHRHRAR VLLISKLSCV 
GIWILATVLS IPELLYSDLQ RSSSEQAMRC SLITEHVEAF ITIQVAQMVI GFLVPLLAMS 
FCYLVIIRTL LQARNFERNK AIKVIIAVVV VFIVFQLPYN GVVLAQTVAN FNITSSTCEL 
SKQLNIAYDV TYSLACVRCC VNPFLYAFIG VKFRNDLFKL FKDLGCLSQE QLRQWSSCRH 
IRRSSMSVEA ETTTTFSP

Genular Protein ID: 2159885216

Symbol: J3KSS9_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KSS9

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 3 RuleBase 1 SAM 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 372
  • Mass: 42232
  • Checksum: 6BAC116ADF458B5B
  • Sequence:
    • MKSVLVVALL VIFQVCLCQD EVTDDYIGDN TTVDYTLFES LCSKKDVRNF KAWFLPIMYS 
IICFVGLLGN GLVVLTYIYF KRLKTMTDTY LLNLAVADIL FLLTLPFWAY SAAKSWVFGV 
HFCKLIFAIY KMSFFSGMLL LLCISIDRYV AIVQAVSAHR HRARVLLISK LSCVGIWILA 
TVLSIPELLY SDLQRSSSEQ AMRCSLITEH VEAFITIQVA QMVIGFLVPL LAMSFCYLVI 
IRTLLQARNF ERNKAIKVII AVVVVFIVFQ LPYNGVVLAQ TVANFNITSS TCELSKQLNI 
AYDVTYSLAC VRCCVNPFLY AFIGVKFRND LFKLFKDLGC LSQEQLRQWS SCRHIRRSSM 
SVEAETTTTF SP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.