CCR8 | ENSG00000179934 | NCBI 1237

Details for: CCR8

Gene ID: 1237

Symbol: CCR8

Ensembl ID: ENSG00000179934

Description: C-C motif chemokine receptor 8

Associated with

Chemokine receptors bind chemokines
(R-HSA-380108)
Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
G alpha (i) signalling events
(R-HSA-418594)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Peptide ligand-binding receptors
(R-HSA-375276)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
C-c chemokine binding
(GO:0019957)
C-c chemokine receptor activity
(GO:0016493)
Calcium-mediated signaling
(GO:0019722)
Cell adhesion
(GO:0007155)
Cell chemotaxis
(GO:0060326)
Chemokine-mediated signaling pathway
(GO:0070098)
Chemokine receptor activity
(GO:0004950)
Chemotaxis
(GO:0006935)
Coreceptor activity
(GO:0015026)
External side of plasma membrane
(GO:0009897)
G protein-coupled receptor signaling pathway
(GO:0007186)
Immune response
(GO:0006955)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)

Other Information

Proteins

C-C chemokine receptor type 8

Genular Protein ID: 3531062816

Symbol: CCR8_HUMAN

Name: C-C chemokine receptor type 8

UniProtKB Accession Codes:

P51685 B2RC64 Q3KNQ8 Q3KNR3 Q9BYX5

Database IDs:

Citations:

PubMed ID: 8886020

Title: Molecular cloning and RNA expression of two new human chemokine receptor-like genes.

PubMed ID: 8886020

DOI: 10.1006/bbrc.1996.1595

PubMed ID: 8977299

Title: Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor.

PubMed ID: 8977299

DOI: 10.1002/eji.1830261230

PubMed ID: 9207005

Title: Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.

PubMed ID: 9207005

DOI: 10.1084/jem.186.1.165

PubMed ID: 8816377

Title: Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues.

PubMed ID: 8816377

PubMed ID: 12551893

Title: Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus.

PubMed ID: 12551893

DOI: 10.1074/jbc.m211422200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9521068

Title: Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor.

PubMed ID: 9521068

DOI: 10.1002/(sici)1521-4141(199802)28:02<582::aid-immu582>3.0.co;2-a

PubMed ID: 9469461

Title: Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3.

PubMed ID: 9469461

PubMed ID: 10540332

Title: The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8.

PubMed ID: 10540332

DOI: 10.1002/(sici)1521-4141(199910)29:10<3210::aid-immu3210>3.0.co;2-w

Sequence Information:

Length: 355
Mass: 40844
Checksum: BC14A153CF695361
Sequence:

MDYTLDLSVT TVTDYYYPDI FSSPCDAELI QTNGKLLLAV FYCLLFVFSL LGNSLVILVL 
VVCKKLRSIT DVYLLNLALS DLLFVFSFPF QTYYLLDQWV FGTVMCKVVS GFYYIGFYSS 
MFFITLMSVD RYLAVVHAVY ALKVRTIRMG TTLCLAVWLT AIMATIPLLV FYQVASEDGV 
LQCYSFYNQQ TLKWKIFTNF KMNILGLLIP FTIFMFCYIK ILHQLKRCQN HNKTKAIRLV 
LIVVIASLLF WVPFNVVLFL TSLHSMHILD GCSISQQLTY ATHVTEIISF THCCVNPVIY 
AFVGEKFKKH LSEIFQKSCS QIFNYLGRQM PRESCEKSSS CQQHSSRSSS VDYIL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CCR8

Associated with

Other Information

Molecular cloning and RNA expression of two new human chemokine receptor-like genes. PubMed ID: 8886020

Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor. PubMed ID: 8977299

Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309. PubMed ID: 9207005

Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues. PubMed ID: 8816377

Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus. PubMed ID: 12551893

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. PubMed ID: 9521068

Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3. PubMed ID: 9469461

The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8. PubMed ID: 10540332