Details for: Casp8
Associated with
Other Information
Genular Protein ID: 1628797015
Symbol: CASP8_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9654089
Title: Molecular cloning and characterization of mouse caspase-8.
PubMed ID: 9654089
PubMed ID: 9837723
Title: Molecular cloning and identification of murine caspase-8.
PubMed ID: 9837723
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9729047
Title: Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
PubMed ID: 9729047
PubMed ID: 12065591
Title: Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2.
PubMed ID: 12065591
PubMed ID: 15383280
Title: Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions.
PubMed ID: 15383280
PubMed ID: 17245429
Title: FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies.
PubMed ID: 17245429
PubMed ID: 17242355
Title: Large-scale phosphorylation analysis of mouse liver.
PubMed ID: 17242355
PubMed ID: 18455983
Title: TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis.
PubMed ID: 18455983
PubMed ID: 19131326
Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
PubMed ID: 19131326
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 23806337
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
PubMed ID: 23806337
PubMed ID: 24813849
Title: RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
PubMed ID: 24813849
PubMed ID: 24813850
Title: RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
PubMed ID: 24813850
PubMed ID: 29440439
Title: Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis.
PubMed ID: 29440439
PubMed ID: 31519887
Title: K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation.
PubMed ID: 31519887
PubMed ID: 30381458
Title: Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection.
PubMed ID: 30381458
PubMed ID: 30361383
Title: Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
PubMed ID: 30361383
PubMed ID: 31511692
Title: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
PubMed ID: 31511692
PubMed ID: 31748744
Title: Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.
PubMed ID: 31748744
PubMed ID: 32971525
Title: Integration of innate immune signaling by caspase-8 cleavage of N4BP1.
PubMed ID: 32971525
PubMed ID: 34471287
Title: AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
PubMed ID: 34471287
PubMed ID: 33397971
Title: ZBP1 promotes LPS-induced cell death and IL-1beta release via RHIM-mediated interactions with RIPK1.
PubMed ID: 33397971
Sequence Information:
- Length: 480
- Mass: 55357
- Checksum: 045268AE3DE5ED4F
- Sequence:
MDFQSCLYAI AEELGSEDLA ALKFLCLDYI PHKKQETIED AQKLFLRLRE KGMLEEGNLS FLKELLFHIS RWDLLVNFLD CNREEMVREL RDPDNAQISP YRVMLFKLSE EVSELELRSF KFLLNNEIPK CKLEDDLSLL EIFVEMEKRT MLAENNLETL KSICDQVNKS LLGKIEDYER SSTERRMSLE GREELPPSVL DEMSLKMAEL CDSPREQDSE SRTSDKVYQM KNKPRGYCLI INNHDFSKAR EDITQLRKMK DRKGTDCDKE ALSKTFKELH FEIVSYDDCT ANEIHEILEG YQSADHKNKD CFICCILSHG DKGVVYGTDG KEASIYDLTS YFTGSKCPSL SGKPKIFFIQ ACQGSNFQKG VPDEAGFEQQ NHTLEVDSSS HKNYIPDEAD FLLGMATVKN CVSYRDPVNG TWYIQSLCQS LRERCPQGDD ILSILTGVNY DVSNKDDRRN KGKQMPQPTF TLRKKLFFPP
Genular Protein ID: 427713908
Symbol: A0A087WQT6_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 17242355
Title: Large-scale phosphorylation analysis of mouse liver.
PubMed ID: 17242355
PubMed ID: 19131326
Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.
PubMed ID: 19131326
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 23806337
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
PubMed ID: 23806337
Sequence Information:
- Length: 500
- Mass: 57821
- Checksum: 4940835E6A3AA80A
- Sequence:
MCVLLELLSD WLQLFYLLIR MDFQSCLYAI AEELGSEDLA ALKFLCLDYI PHKKQETIED AQKLFLRLRE KGMLEEGNLS FLKELLFHIS RWDLLVNFLD CNREEMVREL RDPDNAQISP YRVMLFKLSE EVSELELRSF KFLLNNEIPK CKLEDDLSLL EIFVEMEKRT MLAENNLETL KSICDQVNKS LLGKIEDYER SSTERRMSLE GREELPPSVL DEMSLKMAEL CDSPREQDSE SRTSDKVYQM KNKPRGYCLI INNHDFSKAR EDITQLRKMK DRKGTDCDKE ALSKTFKELH FEIVSYDDCT ANEIHEILEG YQSADHKNKD CFICCILSHG DKGVVYGTDG KEASIYDLTS YFTGSKCPSL SGKPKIFFIQ ACQGSNFQKG VPDEAGFEQQ NHTLEVDSSS HKNYIPDEAD FLLGMATVKN CVSYRDPVNG TWYIQSLCQS LRERCPQGDD ILSILTGVNY DVSNKDDRRN KGKQMPQPTF TLRKKLFFPP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.