Genular: Defining Cellular Identity and Function

Details for: Casp9

Gene ID: 12371

Symbol: Casp9

Ensembl ID: ENSMUSG00000028914

Description: caspase 9

Associated with

Activation of caspases through apoptosome-mediated cleavage
(R-MMU-111459)
Akt phosphorylates targets in the cytosol
(R-MMU-198323)
Apoptosis
(R-MMU-109581)
Apoptotic factor-mediated response
(R-MMU-111471)
Caspase activation via dependence receptors in the absence of ligand
(R-MMU-418889)
Caspase activation via extrinsic apoptotic signalling pathway
(R-MMU-5357769)
Cytochrome c-mediated apoptotic response
(R-MMU-111461)
Formation of apoptosome
(R-MMU-111458)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Intracellular signaling by second messengers
(R-MMU-9006925)
Intrinsic pathway for apoptosis
(R-MMU-109606)
Nod1/2 signaling pathway
(R-MMU-168638)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways
(R-MMU-168643)
Pip3 activates akt signaling
(R-MMU-1257604)
Programmed cell death
(R-MMU-5357801)
Regulation of the apoptosome activity
(R-MMU-9627069)
Signal transduction
(R-MMU-162582)
Activation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0006919)
Apoptosome
(GO:0043293)
Apoptotic process
(GO:0006915)
Caspase complex
(GO:0008303)
Cellular response to dexamethasone stimulus
(GO:0071549)
Cellular response to uv
(GO:0034644)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type endopeptidase activity involved in apoptotic process
(GO:0097153)
Cysteine-type endopeptidase activity involved in apoptotic signaling pathway
(GO:0097199)
Cysteine-type peptidase activity
(GO:0008234)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna damage response
(GO:0006974)
Epithelial cell apoptotic process
(GO:1904019)
Fibroblast apoptotic process
(GO:0044346)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Intrinsic apoptotic signaling pathway
(GO:0097193)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
(GO:0070059)
Mitochondrion
(GO:0005739)
Neuron apoptotic process
(GO:0051402)
Nucleus
(GO:0005634)
Peptidase activity
(GO:0008233)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of neuron apoptotic process
(GO:0043525)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein maturation
(GO:0051604)
Protein processing
(GO:0016485)
Proteolysis
(GO:0006508)
Regulation of apoptotic process
(GO:0042981)
Response to organic cyclic compound
(GO:0014070)
Response to uv
(GO:0009411)
Sh3 domain binding
(GO:0017124)
Signal transduction in response to dna damage
(GO:0042770)

Other Information

Proteins

Caspase-9
A2AS93_MOUSE

Genular Protein ID: 3139477446

Symbol: CASP9_MOUSE

Name: Caspase-9

UniProtKB Accession Codes:

Q8C3Q9

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15657060

Title: c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage.

PubMed ID: 15657060

DOI: 10.1074/jbc.m413787200

Sequence Information:

Length: 454
Mass: 49979
Checksum: 438A67EA66A6EE78
Sequence:

MDEADRQLLR RCRVRLVSEL QVAELWDALL SRELFTRDMI EDIQQAGSGS RRDQARQLVT 
DLETRGRQAL PLFISCLEDT GQGTLASLLQ SGRQAAKQDP EAVKPLDHLV PVVLGPMGLT 
AKEQRVVKLD PSQPAVGNLT PVVLGPEELW PARLKPEVLR PETPRPVDIG SGGAHDVCVP 
GKIRGHADMA YTLDSDPCGH CLIINNVNFC PSSGLGTRTG SNLDRDKLEH RFRWLRFMVE 
VKNDLTAKKM VTALMEMAHR NHRALDCFVV VILSHGCQAS HLQFPGAVYG TDGCSVSIEK 
IVNIFNGSGC PSLGGKPKLF FIQACGGEQK DHGFEVACTS SQGRTLDSDS EPDAVPYQEG 
PRPLDQLDAV SSLPTPSDIL VSYSTFPGFV SWRDKKSGSW YIETLDGILE QWARSEDLQS 
LLLRVANAVS AKGTYKQIPG CFNFLRKKLF FKTS

Genular Protein ID: 1066016840

Symbol: A2AS93_MOUSE

Name: N/A

UniProtKB Accession Codes:

A2AS93

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 405
Mass: 44373
Checksum: 688CA51685F23351
Sequence:

MDEADRQLLR RCRVRLVSEL QVAELWDALL SRELFTRDMI EDIQQAGSGS RRDQARQLVT 
DLETRGRQAL PLFISCLEDT GQGTLASLLQ SGRQAAKQDP EAVKPLDHLV PVVLGPMGLT 
AKEQRVVKLD PSQPAVGNLT PVVLGPEELW PARLKPEVLR PETPRPVDIG SGGAHDVCVP 
GKIRGHADMA YTLDSDPCGH CLIINNVNFC PSSGLGTRTG SNLDRDKLEH RFRWLRFMVE 
VKNDLTAKKM VTALMEMAHR NHRALDCFVV VILSHGCQAS HLQFPGAVYG TDGCSVSIEK 
IVNIFNGSGC PSLGGKPKLF FIQACGGEQK DHGFEVACTS SQGRTLDSDS EPDAVPYQEG 
PRPLDQLDAV SSLPTPSDIL VSYSTFPGCQ CCFCERDLQA DSWLF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Casp9

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. PubMed ID: 15657060

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Database document:

PubMed ID: 16141072

PubMed ID: 19468303

PubMed ID: 15489334

PubMed ID: 15657060

PubMed ID: 19468303