Genular: Defining Cellular Identity and Function

Details for: Cav3

Gene ID: 12391

Symbol: Cav3

Ensembl ID: ENSMUSG00000062694

Description: caveolin 3

Associated with

Actin filament organization
(GO:0007015)
Alpha-tubulin binding
(GO:0043014)
Calcium channel regulator activity
(GO:0005246)
Calcium ion transport
(GO:0006816)
Cardiac muscle cell development
(GO:0055013)
Cardiac muscle hypertrophy
(GO:0003300)
Caveola
(GO:0005901)
Caveola assembly
(GO:0070836)
Cell differentiation
(GO:0030154)
Cell surface
(GO:0009986)
Cholesterol homeostasis
(GO:0042632)
Connexin binding
(GO:0071253)
Cytoplasmic microtubule organization
(GO:0031122)
Detection of muscle stretch
(GO:0035995)
Dystrophin-associated glycoprotein complex
(GO:0016010)
Endocytosis
(GO:0006897)
Endoplasmic reticulum
(GO:0005783)
Enzyme binding
(GO:0019899)
Establishment of localization in cell
(GO:0051649)
Focal adhesion
(GO:0005925)
Glucose homeostasis
(GO:0042593)
Golgi apparatus
(GO:0005794)
Heart trabecula formation
(GO:0060347)
Intercalated disc
(GO:0014704)
Mapk cascade
(GO:0000165)
Membrane
(GO:0016020)
Membrane raft organization
(GO:0031579)
Molecular adaptor activity
(GO:0060090)
Myoblast fusion
(GO:0007520)
Myotube differentiation
(GO:0014902)
Negative regulation of calcium ion transport
(GO:0051926)
Negative regulation of cardiac muscle hypertrophy
(GO:0010614)
Negative regulation of cell growth involved in cardiac muscle cell development
(GO:0061052)
Negative regulation of cell size
(GO:0045792)
Negative regulation of mapk cascade
(GO:0043409)
Negative regulation of map kinase activity
(GO:0043407)
Negative regulation of membrane depolarization during cardiac muscle cell action potential
(GO:1900826)
Negative regulation of nitric-oxide synthase activity
(GO:0051001)
Negative regulation of potassium ion transmembrane transport
(GO:1901380)
Negative regulation of protein kinase activity
(GO:0006469)
Negative regulation of sarcomere organization
(GO:0060299)
Neuromuscular junction
(GO:0031594)
Nitric-oxide synthase binding
(GO:0050998)
Nucleus localization
(GO:0051647)
Plasma membrane
(GO:0005886)
Plasma membrane organization
(GO:0007009)
Plasma membrane repair
(GO:0001778)
Positive regulation of caveolin-mediated endocytosis
(GO:2001288)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of microtubule polymerization
(GO:0031116)
Positive regulation of myotube differentiation
(GO:0010831)
Potassium channel inhibitor activity
(GO:0019870)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein localization
(GO:0008104)
Protein localization to plasma membrane
(GO:0072659)
Regulation of branching involved in mammary gland duct morphogenesis
(GO:0060762)
Regulation of calcium ion import
(GO:0090279)
Regulation of calcium ion transmembrane transporter activity
(GO:1901019)
Regulation of calcium ion transport
(GO:0051924)
Regulation of cardiac muscle cell action potential involved in regulation of contraction
(GO:0098909)
Regulation of cardiac muscle contraction
(GO:0055117)
Regulation of cytosolic calcium ion concentration
(GO:0051480)
Regulation of heart rate
(GO:0002027)
Regulation of membrane depolarization during cardiac muscle cell action potential
(GO:1900825)
Regulation of membrane potential
(GO:0042391)
Regulation of nerve growth factor receptor activity
(GO:0051394)
Regulation of p38mapk cascade
(GO:1900744)
Regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051896)
Regulation of signal transduction by receptor internalization
(GO:0038009)
Regulation of skeletal muscle contraction
(GO:0014819)
Regulation of sodium ion transmembrane transporter activity
(GO:2000649)
Regulation of transforming growth factor beta receptor signaling pathway
(GO:0017015)
Regulation of ventricular cardiac muscle cell membrane depolarization
(GO:0060373)
Regulation of ventricular cardiac muscle cell membrane repolarization
(GO:0060307)
Sarcolemma
(GO:0042383)
Sodium channel regulator activity
(GO:0017080)
T-tubule
(GO:0030315)
Transmembrane transporter binding
(GO:0044325)
Triglyceride metabolic process
(GO:0006641)
Ventricular cardiac muscle cell action potential
(GO:0086005)
Vesicle
(GO:0031982)
Z disc
(GO:0030018)

Other Information

Proteins

M-caveolin

Genular Protein ID: 3768900538

Symbol: CAV3_MOUSE

Name: M-caveolin

UniProtKB Accession Codes:

P51637

Database IDs:

Citations:

PubMed ID: 8521953

Title: M-caveolin, a muscle-specific caveolin-related protein.

PubMed ID: 8521953

DOI: 10.1016/0014-5793(95)01256-7

PubMed ID: 8549793

Title:

PubMed ID: 8549793

DOI: 10.1016/0014-5793(96)82884-5

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19380584

Title: Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin.

PubMed ID: 19380584

DOI: 10.1074/jbc.m109.009589

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 19940021

Title: Caveolin-3 promotes nicotinic acetylcholine receptor clustering and regulates neuromuscular junction activity.

PubMed ID: 19940021

DOI: 10.1091/mbc.e09-05-0381

PubMed ID: 24066022

Title: Popeye domain containing 1 (Popdc1/Bves) is a caveolae-associated protein involved in ischemia tolerance.

PubMed ID: 24066022

DOI: 10.1371/journal.pone.0071100

PubMed ID: 26497963

Title: The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes.

PubMed ID: 26497963

DOI: 10.1152/ajpheart.00446.2015

Sequence Information:

Length: 151
Mass: 17358
Checksum: 7C1A181010CC60F1
Sequence:

MMTEEHTDLE ARIIKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPEG TYSFDGVWKV 
SFTTFTVSKY WCYRLLSTLL GVPLALLWGF LFACISFCHI WAVVPCIKSY LIEIQCISHI 
YSLCIRTFCN PLFAALGQVC SNIKVVLRRE G

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cav3

Associated with

Other Information

M-caveolin, a muscle-specific caveolin-related protein. PubMed ID: 8521953

PubMed ID: 8549793

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin. PubMed ID: 19380584

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Caveolin-3 promotes nicotinic acetylcholine receptor clustering and regulates neuromuscular junction activity. PubMed ID: 19940021

Popeye domain containing 1 (Popdc1/Bves) is a caveolae-associated protein involved in ischemia tolerance. PubMed ID: 24066022

The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes. PubMed ID: 26497963