Details for: Runx1

Gene ID: 12394

Symbol: Runx1

Ensembl ID: ENSMUSG00000022952

Description: runt related transcription factor 1

Associated with

  • Atp binding
    (GO:0005524)
  • Basement membrane
    (GO:0005604)
  • Behavioral response to pain
    (GO:0048266)
  • Calcium ion binding
    (GO:0005509)
  • Cellular response to transforming growth factor beta stimulus
    (GO:0071560)
  • Central nervous system development
    (GO:0007417)
  • Chondrocyte differentiation
    (GO:0002062)
  • Chromatin
    (GO:0000785)
  • Core-binding factor complex
    (GO:0016513)
  • Definitive hemopoiesis
    (GO:0060216)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription factor binding
    (GO:0140297)
  • Dna binding
    (GO:0003677)
  • Embryonic hemopoiesis
    (GO:0035162)
  • Hair follicle morphogenesis
    (GO:0031069)
  • Hemopoiesis
    (GO:0030097)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • In utero embryonic development
    (GO:0001701)
  • Liver development
    (GO:0001889)
  • Myeloid cell differentiation
    (GO:0030099)
  • Myeloid leukocyte differentiation
    (GO:0002573)
  • Myeloid progenitor cell differentiation
    (GO:0002318)
  • Negative regulation of cd4-positive, alpha-beta t cell differentiation
    (GO:0043371)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of granulocyte differentiation
    (GO:0030853)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuron development
    (GO:0048666)
  • Neuron differentiation
    (GO:0030182)
  • Neuron fate commitment
    (GO:0048663)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Ossification
    (GO:0001503)
  • Positive regulation of angiogenesis
    (GO:0045766)
  • Positive regulation of cd8-positive, alpha-beta t cell differentiation
    (GO:0043378)
  • Positive regulation of cell maturation
    (GO:1903431)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of granulocyte differentiation
    (GO:0030854)
  • Positive regulation of interleukin-2 production
    (GO:0032743)
  • Positive regulation of progesterone secretion
    (GO:2000872)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of type ii interferon production
    (GO:0032729)
  • Promoter-specific chromatin binding
    (GO:1990841)
  • Protein-containing complex
    (GO:0032991)
  • Protein binding
    (GO:0005515)
  • Protein heterodimerization activity
    (GO:0046982)
  • Protein homodimerization activity
    (GO:0042803)
  • Regulation of cell differentiation
    (GO:0045595)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of hair follicle cell proliferation
    (GO:0071336)
  • Regulation of signal transduction
    (GO:0009966)
  • Regulation of t cell anergy
    (GO:0002667)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to retinoic acid
    (GO:0032526)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Skeletal system development
    (GO:0001501)
  • Transcription cis-regulatory region binding
    (GO:0000976)
  • Transcription coactivator binding
    (GO:0001223)
  • Transcription corepressor binding
    (GO:0001222)

Other Information

Genular Protein ID: 3908357032

Symbol: G3X9W7_MOUSE

Name: N/A

UniProtKB Accession Codes:

G3X9W7

Database IDs:

AGR 1 ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 1 GeneTree 1 HOGENOM 1 InterPro 7 MGI 2 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

  • Length: 387
  • Mass: 41273
  • Checksum: 24F31E18CD054790
  • Sequence:
    • MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDGGAAL ASKLRSGDRS MVEVLADHPG 
ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG TLVTVMAGND ENYSAELRNA 
TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRNAR 
QIQPSPPWSY DQSYQYLGSI TSSSVHPATP ISPGRASGMT SLSAELSSRL STAPDLTAFG 
DPRQFPTLPS ISDPRMHYPG AFTYSPPVTS GIGIGMSAMS SASRYHTYLP PPYPGSSQAQ 
AGPFQTGSPS YHLYYGASAG SYQFSMVGGE RSPPRILPPC TNASTGAALL NPSLPSQSDV 
VETEGSHSNS PTNMPPARLE EAVWRPY

Genular Protein ID: 792879704

Symbol: G3UWD2_MOUSE

Name: N/A

UniProtKB Accession Codes:

G3UWD2

Database IDs:

AGR 1 ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 1 GeneTree 1 InterPro 7 MGI 2 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1 jPOST 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

  • Length: 451
  • Mass: 48584
  • Checksum: 767BAD6FF4AD4D2E
  • Sequence:
    • MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDGGAAL ASKLRSGDRS MVEVLADHPG 
ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG TLVTVMAGND ENYSAELRNA 
TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR 
QKLDDQTKPG SLSFSERLSE LEQLRRTAMR VSPHHPAPTP NPRASLNHST AFNPQPQSQM 
QDARQIQPSP PWSYDQSYQY LGSITSSSVH PATPISPGRA SGMTSLSAEL SSRLSTAPDL 
TAFGDPRQFP TLPSISDPRM HYPGAFTYSP PVTSGIGIGM SAMSSASRYH TYLPPPYPGS 
SQAQAGPFQT GSPSYHLYYG ASAGSYQFSM VGGERSPPRI LPPCTNASTG AALLNPSLPS 
QSDVVETEGS HSNSPTNMPP ARLEEAVWRP Y

Genular Protein ID: 2696707266

Symbol: Q8BQ09_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BQ09

Database IDs:

AGR 1 ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 EMBL 2 GO 9 Gene3D 1 InterPro 7 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 353
  • Mass: 37848
  • Checksum: C6FED4C6B3998B23
  • Sequence:
    • MAAPPLASKL RSGDRSMVEV LADHPGELVR TDSPNFLCSV LPTHWRCNKT LPIAFKVVAL 
GDVPDGTLVT VMAGNDENYS AELRNATAAM KNQVARFNDL RFVGRSGRGK SFTLTITVFT 
NPPQVATYHR AIKITVDGPR EPRNARQIQP SPPWSYDQSY QYLGSITSSS VHPATPISPG 
RASGMTSLSA ELSSRLSTAP DLTAFGDPRQ FPTLPSISDP RMHYPGAFTY SPPVTSGIGI 
GMSAMSSASR YHTYLPPPYP GSSQAQAGPF QTGSPSYHLY YGASAGSYQF SMVGGERSPP 
RILPPCTNAS TGAALLNPSL PSQSDVVETE GSHSNSPTNM PPARLEEAVW RPY

Genular Protein ID: 1551723006

Symbol: Q3UM65_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UM65

Database IDs:

AGR 1 ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 IntAct 1 InterPro 7 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

  • Length: 465
  • Mass: 50212
  • Checksum: FCBC71AE5F99E957
  • Sequence:
    • MASDSIFESF PSYPQCFMRD ASTSRRFTPP STALSPGKMS EALPLGAPDG GAALASKLRS 
GDRSMVEVLA DHPGELVRTD SPNFLCSVLP THWRCNKTLP IAFKVVALGD VPDGTLVTVM 
AGNDENYSAE LRNATAAMKN QVARFNDLRF VGRSGRGKSF TLTITVFTNP PQVATYHRAI 
KITVDGPREP RRHRQKLDDQ TKPGSLSFSE RLSELEQLRR TAMRVSPHHP APTPNPRASL 
NHSTAFNPQP QSQMQDARQI QPSPPWSYDQ SYQYLGSITS SSVHPATPIS PGRASGMTSL 
SAELSSRLST APDLTAFGDP RQFPTLPSIS DPRMHYPGAF TYSPPVTSGI GIGMSAMSSA 
SRYHTYLPPP YPGSSQAQAG PFQTGSPSYH LYYGASAGSY QFSMVGGERS PPRILPPCTN 
ASTGAALLNP SLPSQSDVVE TEGSHSNSPT NMPPARLEEA VWRPY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.