Details for: ADH1A

Gene ID: 124

Symbol: ADH1A

Ensembl ID: ENSG00000187758

Description: alcohol dehydrogenase 1A (class I), alpha polypeptide

Associated with

Other Information

Genular Protein ID: 2090515616

Symbol: ADH1A_HUMAN

Name: Alcohol dehydrogenase 1A

UniProtKB Accession Codes:

P07327 A8K3E3 Q17R68

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 36 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 DrugCentral 1 EC 2 EMBL 10 Ensembl 1 EvolutionaryTrace 1 GO 12 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 3 RefSeq 1 Rhea 4 SABIO-RK 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3013304

Title: cDNA and protein structure for the alpha subunit of human liver alcohol dehydrogenase.

PubMed ID: 3013304

DOI: 10.1021/bi00357a026

PubMed ID: 2935875

Title: Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.

PubMed ID: 2935875

DOI: 10.1073/pnas.83.3.634

PubMed ID: 2920825

Title: Molecular structure of the human alcohol dehydrogenase 1 gene.

PubMed ID: 2920825

DOI: 10.1016/0014-5793(89)81217-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2347582

Title: The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome.

PubMed ID: 2347582

DOI: 10.1016/0888-7543(90)90535-3

PubMed ID: 2738060

Title: Stereospecific oxidation of secondary alcohols by human alcohol dehydrogenases.

PubMed ID: 2738060

DOI: 10.1016/s0021-9258(18)60436-3

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 15449945

Title: Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors.

PubMed ID: 15449945

DOI: 10.1021/bi0489107

PubMed ID: 11274460

Title: Three-dimensional structures of the three human class I alcohol dehydrogenases.

PubMed ID: 11274460

DOI: 10.1110/ps.45001

Sequence Information:

  • Length: 375
  • Mass: 39859
  • Checksum: B6DF4D57080D9BC1
  • Sequence:
    • MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAVGICGTD DHVVSGTMVT 
PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLAIPQCGK CRICKNPESN YCLKNDVSNP 
QGTLQDGTSR FTCRRKPIHH FLGISTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG 
YGSAVNVAKV TPGSTCAVFG LGGVGLSAIM GCKAAGAARI IAVDINKDKF AKAKELGATE 
CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ 
NLSMNPMLLL TGRTWKGAIL GGFKSKECVP KLVADFMAKK FSLDALITHV LPFEKINEGF 
DLLHSGKSIR TILMF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.