Details for: Cbln1

Gene ID: 12404

Symbol: Cbln1

Ensembl ID: ENSMUSG00000031654

Description: cerebellin 1 precursor protein

Associated with

Other Information

Genular Protein ID: 3592278962

Symbol: CBLN1_MOUSE

Name: Cerebellin-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7877445

Title: Genomic structure and mapping of precerebellin and a precerebellin-related gene.

PubMed ID: 7877445

DOI: 10.1016/0169-328x(94)90196-1

PubMed ID: 9838062

Title: Characterization of transcript processing of the gene encoding precerebellin-1.

PubMed ID: 9838062

DOI: 10.1016/s0169-328x(98)00264-2

PubMed ID: 12106288

Title: A collection of cDNA clones with specific expression patterns in mouse brain.

PubMed ID: 12106288

DOI: 10.1111/j.1460-9568.1990.tb00460.x

PubMed ID: 3199194

Title: Evidence for the transneuronal regulation of cerebellin biosynthesis in developing Purkinje cells.

PubMed ID: 3199194

DOI: 10.1523/jneurosci.08-12-04603.1988

PubMed ID: 3420533

Title: Cerebellin and related postsynaptic peptides in the brain of normal and neurodevelopmentally mutant vertebrates.

PubMed ID: 3420533

DOI: 10.1002/syn.890020203

PubMed ID: 10964938

Title: Cbln3, a novel member of the precerebellin family that binds specifically to Cbln1.

PubMed ID: 10964938

DOI: 10.1523/jneurosci.20-17-06333.2000

PubMed ID: 16135095

Title: The structure and proteolytic processing of Cbln1 complexes.

PubMed ID: 16135095

DOI: 10.1111/j.1471-4159.2005.03385.x

PubMed ID: 16234806

Title: Cbln1 is essential for synaptic integrity and plasticity in the cerebellum.

PubMed ID: 16234806

DOI: 10.1038/nn1576

PubMed ID: 16930405

Title: Distinct expression of Cbln family mRNAs in developing and adult mouse brains.

PubMed ID: 16930405

DOI: 10.1111/j.1460-9568.2006.04950.x

PubMed ID: 17030622

Title: Cbln1 is essential for interaction-dependent secretion of cbln3.

PubMed ID: 17030622

DOI: 10.1128/mcb.01161-06

PubMed ID: 17331201

Title: Characterization of a transneuronal cytokine family Cbln - regulation of secretion by heteromeric assembly.

PubMed ID: 17331201

DOI: 10.1111/j.1460-9568.2007.05361.x

PubMed ID: 19200061

Title: Cbln1 binds to specific postsynaptic sites at parallel fiber-Purkinje cell synapses in the cerebellum.

PubMed ID: 19200061

DOI: 10.1111/j.1460-9568.2009.06639.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20856818

Title: Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.

PubMed ID: 20856818

DOI: 10.1371/journal.pone.0012765

PubMed ID: 20395510

Title: Cbln1 is a ligand for an orphan glutamate receptor delta2, a bidirectional synapse organizer.

PubMed ID: 20395510

DOI: 10.1126/science.1185152

PubMed ID: 21410790

Title: Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions.

PubMed ID: 21410790

DOI: 10.1111/j.1460-9568.2011.07638.x

PubMed ID: 22220752

Title: The Cbln family of proteins interact with multiple signaling pathways.

PubMed ID: 22220752

DOI: 10.1111/j.1471-4159.2012.07648.x

PubMed ID: 23141067

Title: Presynaptically released Cbln1 induces dynamic axonal structural changes by interacting with GluD2 during cerebellar synapse formation.

PubMed ID: 23141067

DOI: 10.1016/j.neuron.2012.07.027

PubMed ID: 24467251

Title: Cbln1 downregulates the formation and function of inhibitory synapses in mouse cerebellar Purkinje cells.

PubMed ID: 24467251

DOI: 10.1111/ejn.12487

PubMed ID: 29782851

Title: Glycosylation of Cblns attenuates their receptor binding.

PubMed ID: 29782851

DOI: 10.1016/j.brainres.2018.05.022

PubMed ID: 29691328

Title: Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions Throughout the Brain.

PubMed ID: 29691328

DOI: 10.1523/jneurosci.0360-18.2018

Sequence Information:

  • Length: 193
  • Mass: 21113
  • Checksum: A23C796C7D11BE5F
  • Sequence:
  • MLGVVELLLL GTAWLAGPAR GQNETEPIVL EGKCLVVCDS NPTSDPTGTA LGISVRSGSA 
    KVAFSAIRST NHEPSEMSNR TMIIYFDQVL VNIGNNFDSE RSTFIAPRKG IYSFNFHVVK 
    VYNRQTIQVS LMLNGWPVIS AFAGDQDVTR EAASNGVLIQ MEKGDRAYLK LERGNLMGGW 
    KYSTFSGFLV FPL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.