Genular: Defining Cellular Identity and Function

Details for: Cbx2

Gene ID: 12416

Symbol: Cbx2

Ensembl ID: ENSMUSG00000025577

Description: chromobox 2

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Rna polymerase ii transcription
(R-MMU-73857)
Runx1 interacts with co-factors whose precise effect on runx1 targets is not known
(R-MMU-8939243)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of chromatin organization proteins
(R-MMU-4551638)
Sumoylation of dna damage response and repair proteins
(R-MMU-3108214)
Sumoylation of rna binding proteins
(R-MMU-4570464)
Sumoylation of transcription cofactors
(R-MMU-3899300)
Transcriptional regulation by runx1
(R-MMU-8878171)
Chromatin binding
(GO:0003682)
Chromatin organization
(GO:0006325)
Chromosome
(GO:0005694)
Development of primary sexual characteristics
(GO:0045137)
Dna binding
(GO:0003677)
Euchromatin
(GO:0000791)
Heterochromatin
(GO:0000792)
Methylated histone binding
(GO:0035064)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pcg protein complex
(GO:0031519)
Prc1 complex
(GO:0035102)
Protein binding
(GO:0005515)

Other Information

Proteins

Chromobox protein homolog 2
Q3URA3_MOUSE

Genular Protein ID: 3226337767

Symbol: CBX2_MOUSE

Name: Chromobox protein homolog 2

UniProtKB Accession Codes:

P30658 A2ABG2 O35731 Q8CIA0

Database IDs:

Citations:

PubMed ID: 1352241

Title: The mouse has a Polycomb-like chromobox gene.

PubMed ID: 1352241

DOI: 10.1242/dev.114.4.921

PubMed ID: 9312051

Title: Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.

PubMed ID: 9312051

DOI: 10.1093/emboj/16.19.5930

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16537902

Title: Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin.

PubMed ID: 16537902

DOI: 10.1128/mcb.26.7.2560-2569.2006

PubMed ID: 22226355

Title: Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

PubMed ID: 22226355

DOI: 10.1016/j.stem.2011.12.006

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 519
Mass: 54918
Checksum: F89EF3CEF14ACA72
Sequence:

MEELSSVGEQ VFAAECILSK RLRKGKLEYL VKWRGWSSKH NSWEPEENIL DPRLLLAFQK 
KEHEKEVQNR KRGKRPRGRP RKHTVTSSCS RRSKLKEPDA PSKSKSSSSS SSSTSSSSSS 
DEEEDDSDLD SKRGPRGRET HPVPQKKAQI LVAKPELKDP IRKKRGRKPL PPEQKAARRP 
VSLAKVLKTT RKDLGTSAAK LPPPLSAPVA GLAALKAHTK EACGGPSTMA TPENLASLMK 
GMAGSPSRGG IWQSSIVHYM NRMSQSQVQA ASRLALKAQA TNKCGLGLDL KVRTQKGGEL 
GGSPAGGKVP KAPGGGAAEQ QRGNHSGSPG AQLAPTQELS LQVLDLQSVK NGVPGVGLLA 
RHAPAKAIPA TNPATGKGPG SGPTGANMTN APTDNNKGEK LTCKATALPA PSVKRDTVKS 
VAASGGQEGH TAPGEGRKPP ALSELSTGEE NSSSDSDPDS TSLPSAAQNL SVAIQTSQDW 
KPTRSLIEHV FVTDVTANLI TVTVKESPTS VGFFNLRHY

Genular Protein ID: 1225005588

Symbol: Q3URA3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3URA3

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 136
Mass: 14225
Checksum: 0315C883AA405821
Sequence:

TGANMTNAPT DNNKGEKLTC KATALPAPSV KRDTVKSVAA SGGQEGHTAP GEGRKPPALS 
ELSTGEENSS SDSDPDSTSL PSAAQNLSVA IQTSQDWKPT RSLIEHVFVT DVTANLITVT 
VKESPTSVGF FNLRHY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cbx2

Associated with

Other Information

The mouse has a Polycomb-like chromobox gene. PubMed ID: 1352241

Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain. PubMed ID: 9312051

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. PubMed ID: 16537902

Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. PubMed ID: 22226355

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073