Genular: Defining Cellular Identity and Function

Details for: Cbx4

Gene ID: 12418

Symbol: Cbx4

Ensembl ID: ENSMUSG00000039989

Description: chromobox 4

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Rna polymerase ii transcription
(R-MMU-73857)
Runx1 interacts with co-factors whose precise effect on runx1 targets is not known
(R-MMU-8939243)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of chromatin organization proteins
(R-MMU-4551638)
Sumoylation of dna damage response and repair proteins
(R-MMU-3108214)
Sumoylation of rna binding proteins
(R-MMU-4570464)
Sumoylation of transcription cofactors
(R-MMU-3899300)
Transcriptional regulation by runx1
(R-MMU-8878171)
Chromatin binding
(GO:0003682)
Chromatin organization
(GO:0006325)
Enzyme binding
(GO:0019899)
Methylated histone binding
(GO:0035064)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pcg protein complex
(GO:0031519)
Phosphoprotein binding
(GO:0051219)
Prc1 complex
(GO:0035102)
Protein binding
(GO:0005515)
Protein sumoylation
(GO:0016925)
Single-stranded rna binding
(GO:0003727)
Sumo binding
(GO:0032183)
Sumo ligase activity
(GO:0061665)
Sumo transferase activity
(GO:0019789)
Transcription cis-regulatory region binding
(GO:0000976)
Transferase activity
(GO:0016740)

Other Information

Proteins

E3 SUMO-protein ligase CBX4

Genular Protein ID: 2975871238

Symbol: CBX4_MOUSE

Name: E3 SUMO-protein ligase CBX4

UniProtKB Accession Codes:

O55187 Q149G5 Q149G6

Database IDs:

Citations:

PubMed ID: 9367786

Title: MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

PubMed ID: 9367786

DOI: 10.1006/jmbi.1997.1372

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16537902

Title: Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin.

PubMed ID: 16537902

DOI: 10.1128/mcb.26.7.2560-2569.2006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22226355

Title: Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

PubMed ID: 22226355

DOI: 10.1016/j.stem.2011.12.006

PubMed ID: 22872859

Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.

PubMed ID: 22872859

DOI: 10.1074/mcp.m112.017194

Sequence Information:

Length: 551
Mass: 60523
Checksum: 382F8305FD803CF3
Sequence:

MELPAVGEHV FAVESIEKKR IRKGRVEYLV KWRGWSPKYN TWEPEENILD PRLLIAFQNR 
ERQEQLMGYR KRGPKPKPLV VQVPTFARRS NVLTGLQDSS ADNRAKLELG TQGKGQGHQY 
ELNSKKHHQY QPHSKERSGK PPPPGKSGKY YYQLNSKKHH PYQPDPKMYD LQYQGGHKEA 
PSPTCPDLGT KSHPPDKWAH GAAAKGYLGA VKPLGGGAGA PGKGSEKGPP NGMTPAPKEA 
VTGNGIGGKM KIVKNKNKNG RIVIVMSKYM ENGMQAVKIK SGEAAEGEAR SPSHKKRAAE 
ERHPQGDRTF KKAAGASEEK KAEVPCKRRE EEALVSGDAQ PQDLGSRKLS PTKEAFGEQP 
LQLTTKPDLL AWDPARSSHP PAHHHHHHHH HHHHHTVGLN LSHARKRCLS ETHGEREPCK 
KRLTARSIST PTCLGGSPVS EHPANVSPTA ASLPQPEVIL LDSDLDEPID LRCVKMRSDA 
GEPPSTLQVK PEAPAVAAVV APAPASEKPP AEAQEEPVEP LSEFKPFFGN IIITDVTANC 
LTVTFKEYVT V

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cbx4

Associated with

Other Information

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex. PubMed ID: 9367786

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. PubMed ID: 16537902

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. PubMed ID: 22226355