Genular: Defining Cellular Identity and Function

Details for: Cbx5

Gene ID: 12419

Symbol: Cbx5

Ensembl ID: ENSMUSG00000009575

Description: chromobox 5

Associated with

Factors involved in megakaryocyte development and platelet production
(R-MMU-983231)
Hemostasis
(R-MMU-109582)
Chromatin binding
(GO:0003682)
Chromatin organization
(GO:0006325)
Chromocenter
(GO:0010369)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome, telomeric region
(GO:0000781)
Dna-binding transcription factor binding
(GO:0140297)
Dna damage response
(GO:0006974)
Heterochromatin
(GO:0000792)
Histone deacetylase binding
(GO:0042826)
Histone deacetylase complex
(GO:0000118)
Histone methyltransferase complex
(GO:0035097)
Identical protein binding
(GO:0042802)
Kinetochore
(GO:0000776)
Methylated histone binding
(GO:0035064)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pericentric heterochromatin
(GO:0005721)
Pml body
(GO:0016605)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)
Ribonucleoprotein complex
(GO:1990904)
Ribonucleoprotein complex binding
(GO:0043021)
Site of dna damage
(GO:0090734)
Transcription repressor complex
(GO:0017053)

Other Information

Proteins

Chromobox protein homolog 5

Genular Protein ID: 2139672271

Symbol: CBX5_MOUSE

Name: Chromobox protein homolog 5

UniProtKB Accession Codes:

Q61686 Q9CS35 Q9CXD1

Database IDs:

Citations:

PubMed ID: 8978696

Title: A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

PubMed ID: 8978696

PubMed ID: 11107181

Title: Contiguous arrangement of p45 NFE2, HnRNP A1, and HP1 alpha on mouse chromosome 15 and human chromosome 12: evidence for suppression of these genes due to retroviral integration within the Fli-2 locus.

PubMed ID: 11107181

DOI: 10.1002/1098-2264(2000)9999:9999<::aid-gcc1058>3.3.co;2-1

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10562550

Title: Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.

PubMed ID: 10562550

DOI: 10.1093/emboj/18.22.6385

PubMed ID: 15145825

Title: A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.

PubMed ID: 15145825

DOI: 10.1101/gad.300704

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 28250819

Title: SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation.

PubMed ID: 28250819

DOI: 10.1186/s13072-017-0115-7

Sequence Information:

Length: 191
Mass: 22186
Checksum: 8AB87E2F00DB8C40
Sequence:

MGKKTKRTAD SSSSEDEEEY VVEKVLDRRM VKGQVEYLLK WKGFSEEHNT WEPEKNLDCP 
ELISEFMKKY KKMKEGENNK PREKSEGNKR KSSFSNSADD IKSKKKREQS NDIARGFERG 
LEPEKIIGAT DSCGDLMFLM KWKDTDEADL VLAKEANVKC PQIVIAFYEE RLTWHAYPED 
AENKEKESAK S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cbx5

Associated with

Other Information

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. PubMed ID: 8978696

Contiguous arrangement of p45 NFE2, HnRNP A1, and HP1 alpha on mouse chromosome 15 and human chromosome 12: evidence for suppression of these genes due to retroviral integration within the Fli-2 locus. PubMed ID: 11107181

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. PubMed ID: 10562550

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. PubMed ID: 15145825

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SMYD5 regulates H4K20me3-marked heterochromatin to safeguard ES cell self-renewal and prevent spurious differentiation. PubMed ID: 28250819